Results 71 to 80 of about 365,982 (310)

Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet, Sylvie A. Adams, Zoe S. Katz, Christal G. Delagrammatikas, Kosuke Izumi, Winifred Sigal, Kim Ventarola, Elaine H. Zackai, Julia E. Reid, Grant T. Liu, Jennifer M. Kalish   +10 more
wiley   +1 more source

Pituitary apoplexy

Neurologia i Neurochirurgia Polska, 2019
Pituitary apoplexy (PA) is a clinical syndrome caused by acute haemorrhage and/or infarction of the pituitary gland, generally within a frequently undiagnosed pituitary adenoma. The sudden increase in pituitary gland volume is responsible for typical symptoms: severe headache, nausea, vomiting, visual impairment, cranial nerve palsies, deteriorating ...
Małgorzata, Wichlińska-Lubińska, Grzegorz, Kozera   +1 more
openaire   +3 more sources

Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma [PDF]

, 1985
Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica.
Lüdecke, D. K., Rohrmoser, B., B. Rohrmoser, D. K. Liidecke, Scriba, Peter Christian, P. C. Scriba T   +5 more
core   +1 more source

Discrimination between non-functioning pituitary adenomas and hypophysitis using machine learning methods based on magnetic resonance imaging-derived texture features

, 2022
Purpose Hypophysitis is a heterogeneous condition that includes inflammation of the pituitary gland and infundibulum, and it can cause symptoms related to mass effects and hormonal deficiencies. We aimed to evaluate the potential role of machine learning
YILDIZ, GÖKÇEN, ÇOMUNOĞLU, NİL, KADIOĞLU, PINAR, Oguz, Kader Karli, Durcan, Emre, Erbas, Tomris, DAĞDELEN, SELÇUK, Soylemezoglu, Figen, Sahin, Serdar, ÇİÇEK, EBRU, Oguz, Seda Hanife, KIZILKILIÇ, OSMAN, CIVAN, ORKUN, ÖZKAYA, HANDE MEFKURE, ÖZ, AYŞİM BÜGE   +14 more
core   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source

G protein mutations in pituitary tumors: A study on Turkish patients

, 2003
Activating mutations of the G proteins, G8α (gsp) and Gi2a. (gip) have been reported in subsets of pituitary tumors. The objective of the study was to assess the frequency of gsp and gip mutations in pituitary tumors from Turkish patients and to ...
NACAR, CEVDET
core   +3 more sources

Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region

International Archives of Otorhinolaryngology, 2014
Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis, Amy Eisenberg, Garni Barkhoudarian, Chester Griffiths, Daniel F. Kelly   +4 more
doaj   +1 more source

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Emma F. Barry, Lindsay Durr, Kevin Aaron Fenix, P. J. Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Identifying Facial Features and Predicting Patients of Acromegaly Using Three-Dimensional Imaging Techniques and Machine Learning

Frontiers in Endocrinology, 2020
Objective: Facial changes are common among nearly all acromegalic patients. As they develop slowly, patients often fail to notice such changes before they become obvious. Consequently, diagnosis and treatment are often delayed.
Tian Meng, Xiaopeng Guo, Xiaopeng Guo, Xiaopeng Guo, Wei Lian, Wei Lian, Wei Lian, Kan Deng, Kan Deng, Kan Deng, Lu Gao, Lu Gao, Lu Gao, Zihao Wang, Zihao Wang, Zihao Wang, Jiuzuo Huang, Xiaojun Wang, Xiao Long, Bing Xing, Bing Xing, Bing Xing   +21 more
doaj   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source