Results 61 to 70 of about 552,864 (311)
Causal associations of COVID‐19 on neurosurgical diseases risk: a Mendelian randomization study
Human GenomicsMany researchers have explored the potential association between one neurosurgical disease and coronavirus disease 2019 (COVID-19), but few systematically analyzed the association and causality between COVID-19 and various neurosurgical diseases.
Lirui Dai +3 more
doaj +1 more source
Endocrinology, Diabetes & Metabolism Case Reports, 2020 Gonadotropin-releasing hormone (GnRH) agonists, currently used in the treatment of advanced prostate cancer, have been described as a rare cause of pituitary apoplexy, a potentially life-threatening clinical condition. We report the case of a 69-year-old
Mariana Barbosa +4 more
doaj +1 more source
Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]
, 2014 Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve +4 more
core +2 more sources
Reproduction, 2001 Pituitary tumours are a common type of intracranial neoplasm and, depending on the cell type of origin, have diverse endocrine and reproductive effects. The developmental biology of the different cell types is understood to result from a sequential activation of a cascade of transcription factors, and mutations in these factors result in various forms ...
J R, Davis, W E, Farrell, R N, Clayton
openaire +2 more sources
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Endocrine JournalThe 2017 World Health Organization classification described aggressive pituitary neuroendocrine tumor (PitNET) as “a tumor with strong invasiveness and rapid growth, which is difficult to treat with surgery, radiation therapy, or drug therapy,” which ...
Atsushi Ishida +8 more
doaj +1 more source
55-year-old Woman with Headache, Vomiting, and Visual Disturbance [PDF]
, 2020 Case Presentation: A 55-year-old woman with a past medical history of hypertension, hyperlipidemia, and iron deficiency anemia presented to the emergency department with three days of headache, nausea, vomiting, and visual changes.
Murano, Tiffany +2 more
core
Effects of loperamide on the human hypothalamo-pituitary-adrenal axis in vivo and in vitro. [PDF]
, 1992 Loperamide, an opiate agonist of high specificity for p-receptors, was recently reported to suppress ACTH and cortisol levels in normal subjects, but not in patients with proven ACTH-dependent Cushing’s disease. However, there is little information on
Auernhammer, Christoph J. +4 more
core +1 more source
Paving the Way to Elucidate Hg's Role in Tumorigenesis
Advanced Science, EarlyView.Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li +10 more
wiley +1 more source
Lactate dehydrogenase A promotes the invasion and proliferation of pituitary adenoma
Scientific Reports, 2017 Lactate dehydrogenase A (LDHA) has been reported to be involved in the initiation and progression of tumors. However, the potential role of LDHA in pituitary adenoma (PA) remains unknown.
Jiayin An +9 more
doaj +1 more source