Results 81 to 90 of about 365,982 (310)

Translational Windows in Chordoma: A Target Appraisal

Frontiers in Neurology, 2020
Chordomas are rare tumors that are notoriously refractory to chemotherapy and radiotherapy when radical surgical resection is not achieved or upon recurrence after maximally aggressive treatment.
Samantha E. Hoffman, Sally A. Al Abdulmohsen, Saksham Gupta, Blake M. Hauser, David M. Meredith, Ian F. Dunn, Wenya Linda Bi   +6 more
doaj   +1 more source

Pituitary apoplexy : can histopathology, radiological imaging and predisposing factors be used in predicting outcome?

, 2008
Includes abstract.Includes bibliographical references (leaves 98-112).Pituitary apoplexy is an uncommon, yet potentially fatal illness, usually the result of infarction, hemorrhage or a combination of both in a pituitary tumor.
Semple, Patrick Lyle
core  

Predisposing factors for pituitary apoplexy

, 2014
Pituitary apoplexy is a rare threatening condition, still often misdiagnosed. In line with this the treating physician should be aware of pituitary apoplexy as a potential diagnoses whenever a patient seeks care with acute-onset headache associated with ...
Cirqueira, Cinthya Dos S. [UNESP], Felicio, Andre C., Chang, Claudia V., Araujo, Ricardo V., Nunes, Vânia Dos S. [UNESP]   +4 more
core   +1 more source

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

Animal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee, Yoongeun Kim, Hyungjun Kim, Dae‐Hyun Hahm   +3 more
wiley   +1 more source

Pituitary Tuberculoma

Journal of the College of Physicians and Surgeons Pakistan, 2018
Tuberculosis rarely involves the hypothalamo-pituitary region and constitutes only 1% of the lesions involving the sellar and/or suprasellar region. Coleman and Meredith first reported pituitary tuberculosis in 1940, and only a handful of cases have been reported ever since.
Amir Humza, Sohail, Umar Farooq, Bhatti, Najmul, Islam   +2 more
openaire   +2 more sources

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Pituitary headache

, 2015
The ready access to brain imaging has resulted in an increased detection of incidentally discovered pituitary lesions. Radiological and post mortem studies report the prevalence of pituitary incidentalomas to be as high as 10%.1 Exclusion of secondary ...
Miles J Levy
core   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Management of Intracranial Perforator Aneurysms

Stroke: Vascular and Interventional Neurology
Intracranial perforator aneurysms are rare but potentially life‐threatening vascular lesions that can lead to subarachnoid hemorrhage. Initial imaging is frequently negative, so a high level of suspicion is important for efficient detection of perforator
Karthik Papisetty, Sam J. Schulz, Rajiv Dharnipragada, Andrew S. Venteicher   +3 more
doaj   +1 more source

A detailed redescription of a skeletally immature ‘Redondasaurus’ suggests ontogenetic transformations in the taxon mirror phytosaurian morphological evolution

The Anatomical Record, EarlyView.
Abstract The study of morphological evolution is fundamentally tied to ontogeny, yet studies of these heterochronic processes in the fossil record are rare. Fossils belonging to an ontogenetic series are difficult to assign to an ontogenetic stage due to inconsistent proxies for skeletal ages, challenging to taxonomically assign due to morphological ...
Erika R. Goldsmith, Michelle R. Stocker
wiley   +1 more source