Results 121 to 130 of about 365,982 (310)

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Pituitary Surgery - A Modern Approach /

, 2006
The management of pituitary adenomas and other sellar tumors is one of the most difficult tasks for neurosurgeons and endocrinologists. Optimal treatment requires a multidisciplinary approach; neurological, ophthalmological, and endocrinological tests ...
Laws Jr., E.R.
core  

Complications of endoscopic surgery of the pituitary adenomas: analysis of 570 patients and review of the literature

, 2011
Endoscopic transsphenoidal surgery is emerging as a minimally invasive and maximally effective procedure for pituitary adenomas. In this report we analyzed the complications in 624 procedures of endonasal transsphenoidal endoscopic surgery in the ...
Hazer, Derya Burcu, Cila, Aysenur, Alper Gürlek, Derya Burcu Hazer, Onerci, Metin, Aldur, MUHAMMET MUSTAFA, Ayşenur Cila, BERKER, MUSTAFA, Aldur, Mustafa, Mustafa Aldur, Yucel, Taşkın, Yucel, Taskin, Mustafa Berker, Taşkın Yücel, Gurlek, Alper, Metin Önerci   +15 more
core   +1 more source

Detection of the GH Analogue Redalsomatropin Alfa in Sports Drug Testing: Immunological Approaches and LC‐HRMS/MS

Drug Testing and Analysis, EarlyView.
After evaluating the compatibility of the GH analogue redalsomatropin alfa with approved doping control immunoassays for rhGH, it was implemented into the existing detection method for somatrogon employing affinity purification with GHR‐Fc‐conjugated magnetic beads, tryptic digestion, and LC‐HRMS/MS to allow for a specific and sensitive detection ...
Katja Walpurgis, Andreas Thomas, Jasmin Thelen, Bettina Majer, Maneera Al‐Jaber, Wadha Abushareeda, Mario Thevis   +6 more
wiley   +1 more source

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

Drug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz, Linus Korsmeier, Andreas Thomas, Mario Thevis   +3 more
wiley   +1 more source

Technical nuances for maximising the sublacerum versus supralacerum expanded endoscopic endonasal transclival approach: maximing extent of resection of chordomas, chondrosarcomas and petroclival lesions

Brain and Spine, 2022
A. Zammit, P. Gimenez, W. Ramcharan, J. Sinnott, W. Bennett, K. Abhinav   +5 more
doaj   +1 more source

Comparison of three methods for the estimation of the pituitary gland volume using magnetic resonance imaging: a stereological study

, 2010
Stereological techniques using point counting and planimetry have been used to estimate pituitary gland volume. However, many studies have estimated pituitary gland volume by the mathematical approach the elliptic formula.
Niyazi Acer, Özlem Özçelik, özçelik, Ozlem, Turgut, Mehmet, Mehmet Turgut, Kenan Aycan, Tolga Ertekin, ACER, Niyazi, Turgut, Ahmet, Turgut, Ahmet T., AYCAN, Kenan, Ertekin, Tolga, Ahmet T. Turgut   +12 more
core   +1 more source

Elimination Profile of Deflazacort and Metabolites in Urine and Plasma Following Oral Administration: Relevance to Sports Drug Testing

Drug Testing and Analysis, EarlyView.
Results confirm that the MRL of 30 ng/mL for 21‐desacetyl‐deflazacort together with a 3‐day washout period is an appropriated strategy to detect oral deflazacort administration in sport competition. ABSTRACT Deflazacort (DEF) is a glucocorticoid prohibited in sports competitions when orally administered.
Sergi Coll, Claudia Bressan, Núria Monfort, Ana Aldea‐Perona, Marcel·lí Carbó, Rosa Ventura   +5 more
wiley   +1 more source

Identifying research priorities for pituitary adenoma surgery: an international Delphi consensus statement

Purpose Pituitary surgery is the mainstay treatment for most pituitary adenomas, but many questions remain about perioperative and long-term management and outcomes.
Kolias, AG, Baldeweg, Stephanie E., Geltzeiler, Mathew, Fleseriu, Maria, Koulouri, Olympia, Serrano, I, Drake, William M., Fernandez-Miranda, JC, Fleseriu, M, Gurnell, M, Valetopoulou, A, Melmed, S, Schwartz, Theodore H., Borg, A, Baldeweg, SE, Melmed, Shlomo, Borg, Anouk, Bremner, Fion, Layard Horsfall, H, Buchfelder, Michael, Schwartz, TH, Ginn, J, Kolias, Angelos G., Santarius, T, McBride, Pat, Zada, Gabriel, Dorward, N, Khan, Danyal Z., Bouloux, PMG, Koulouri, O, Miszkiel, KA, Raverot, G, Gurnell, Mark, Newall, Nicola, Kosmin, Michael, Jaunmuktane, Zane, Drake, WM, Buchfelder, M, Harris, Steve, McCormack, AI, Newall, N, McCormack, Ann I., Mamelak, Adam N., Ginn, Joy, Korbonits, Márta, Bremner, F, PitCop Collaborative, Cudlip, Simon, Raverot, Gerald, Geltzeiler, M, Fernandez-Miranda, Juan C., Bouloux, Pierre M. G., Marcus, Hani J., Khan, DZ, Mamelak, AN, Marcus, HJ, Harris, S, Kosmin, M, Santarius, Thomas, Mannion, R, Mannion, Richard, Serrano, Inma, McBride, P, Zada, G, Miszkiel, Katherine A., Valetopoulou, Alexandra, Korbonits, M, Cudlip, S, Layard Horsfall, Hugo, Jaunmuktane, Z, Dorward, Neil   +70 more
core   +1 more source

Clinicopathological significance of baseline T2-weighted signal intensity in functional pituitary adenomas

, 2018
Purpose To assess baseline T2-weighted signal intensity (T2-WSI) of functional pituitary adenomas (FPA), and to investigate the relationship of baseline T2-WSI with clinical features, histopathological granulation patterns, and response to treatment in ...
Bilgic, Bilge, Tanrikulu, Seher, Sakin Tekin, Dogansen, Sema Ciftci, Yarman, Sema, Sema Yarman, Yalin, Gulsah Yenidunya, Gulsah Yenidunya Yalin, Bilge Bilgic, Sema Ciftci Dogansen, Sencer, Serra, Nihan Nizam, Tekin, Sakin, Serra Sencer, Nizam, Nihan, Seher Tanrikulu   +15 more
core   +1 more source