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Pituitary apoplexy (spontaneous pituitary necrosis) [PDF]

Postgraduate Medical Journal, 1981
Summary Pituitary apoplexy or spontaneous pituitary necrosis is an ill-understood clinical syndrome. It may occur as a neurological emergency requiring urgent interference in a patient with a known pituitary dysfunction or it may be responsible for drawing attention to an as yet unrecognized pituitary pathology. It has a bizarre clinical
Y, Sachdev, K, Gopal, V K, Garg, S S, Mongia   +3 more
openaire   +2 more sources

Automatic Detection for Acromegaly Using Hand Photographs: A Deep-Learning Approach

IEEE Access, 2021
Machine learning assisted diagnosis of acromegaly from facial photographs has been proved feasible in recent years. According to our previous research, facial and limb changes exist in patients with acromegaly at early stage.
Chengbin Duan, Wenli Chen, Shun Yao, Zhigang Mao, Zongming Wang, Bin Hu, Haosen Jiao, Dimin Zhu, Yonghong Zhu, Haijun Wang   +9 more
doaj   +1 more source

Generation of isogenic and homozygous MEN1 mutant cell lines from patient-derived iPSCs using CRISPR/Cas9

Stem Cell Research, 2023
MEN1, an autosomal dominant disorder caused by mutations in the tumor suppressor gene MEN1, manifests with co-occurrence of multiple endocrine/neuroendocrine neoplasms. An iPSC line derived from an index patient carrying the mutation c.1273C>T (p.Arg465*)
Naomi Even-Zohar, Derya Metin-Armagan, Anat Ben-Shlomo, Dhruv Sareen, Shlomo Melmed   +4 more
doaj   +1 more source

The Clinical and Pathological Characteristics of Refractory Pituitary Adenomas: A Single Center Experience

Frontiers in Oncology, 2022
BackgroundMost of pituitary adenomas (PAs) are slow-growing benign tumors which can be cured or controlled by conventional therapies, including surgery, medical treatment or radiotherapy.
Xiaohai Liu, Xiaohai Liu, Congxin Dai, Congxin Dai, Xinjie Bao, Xinjie Bao, Kan Deng, Kan Deng, Yong Yao, Yong Yao, Ming Feng, Ming Feng, Mingchu Li, Mingchu Li, Ge Chen, Ge Chen, Renzhi Wang, Renzhi Wang   +17 more
doaj   +1 more source

Treatment of Aggressive Pituitary Adenomas: A Case-Based Narrative Review

Frontiers in Endocrinology, 2021
Management of aggressive pituitary adenomas is challenging due to a paucity of rigorous evidence supporting available treatment approaches. Recent guidelines emphasize the need to maximize standard therapies as well as the use of temozolomide and ...
Odelia Cooper, Vivien Bonert, Ning-Ai Liu, Adam N. Mamelak, Adam N. Mamelak   +4 more
doaj   +1 more source

Preoperative Fasting C-Peptide Acts as a Promising Predictor of Improved Glucose Tolerance in Patients With Acromegaly After Transsphenoidal Surgery: A Retrospective Study of 64 Cases From a Large Pituitary Center in China

Frontiers in Endocrinology, 2019
Purpose: Abnormal glucose metabolism is one of the most frequent acromegaly complications. Improvement of glucose metabolism can be observed only in half of acromegaly patients after surgery.
Zihao Wang, Zihao Wang, Lu Gao, Lu Gao, Xiaopeng Guo, Xiaopeng Guo, Chenzhe Feng, Chenzhe Feng, Kan Deng, Kan Deng, Wei Lian, Wei Lian, Ming Feng, Ming Feng, Xinjie Bao, Xinjie Bao, Bing Xing, Bing Xing   +17 more
doaj   +1 more source

IgG4-Related Inflammatory Pseudotumor Involving the Clivus: A Case Report and Literature Review

Frontiers in Endocrinology, 2021
IgG4-related inflammatory pseudotumors are very uncommon and are characterized histologically by the presence of inflammatory swellings with increasing IgG4-positive plasma cells and lymphocytes infiltrating the tissues.
Xiaohai Liu, Xiaohai Liu, Renzhi Wang, Renzhi Wang, Mingchu Li, Mingchu Li, Ge Chen, Ge Chen   +7 more
doaj   +1 more source

Prediction of the Recurrence of Non-Functioning Pituitary Adenomas Using Preoperative Supra-Intra Sellar Volume and Tumor-Carotid Distance

Frontiers in Endocrinology, 2021
BackgroundCurrently, it is difficult to estimate the possibility of recurrence of nonfunctioning pituitary adenomas (NFPAs). Markers such as Ki-67 or transcription factors rely on postoperative pathology, while few indices can be used for preoperative ...
Wenli Chen, Mengqi Wang, Chengbin Duan, Shun Yao, Haosen Jiao, Zongming Wang, Bin Hu, Zhigang Mao, Yonghong Zhu, Haijun Wang   +9 more
doaj   +1 more source

Sub-macroscopic skin presentation of acromegaly and effect of pituitary tumor surgery: A study using dermatoscopy and ultra-high-frequency ultrasound

Frontiers in Endocrinology, 2023
ObjectiveExcessive growth hormone and insulin-like growth factor 1 contribute to cutaneous changes in acromegaly. We investigated the sub-macroscopic skin manifestation of acromegaly patients and explored its reversibility upon hormone reduction after ...
Xiaopeng Guo, Yukun Wang, Yong Yao, Xinjie Bao, Lian Duan, Huijuan Zhu, Bing Xing, Jie Liu   +7 more
doaj   +1 more source

Pituitary Metastasis of Lung Neuroendocrine Carcinoma Mimicking Pituitary Adenoma:Case Report and Literature Review

Frontiers in Endocrinology, 2021
Pituitary metastasis is an unusual situation in clinical practice, while the incidence is increasing with age. Breast cancer for women and lung cancer for men were the most frequent primary origins of pituitary metastasis.
Xiaohai Liu, Xiaohai Liu, Renzhi Wang, Renzhi Wang, Mingchu Li, Mingchu Li, Ge Chen, Ge Chen   +7 more
doaj   +1 more source