Results 11 to 20 of about 574,474 (315)

Pilot study to define criteria for Pituitary Tumors Centers of Excellence (PTCOE): results of an audit of leading international centers

Pituitary, 2023
The Pituitary Society established the concept and mostly qualitative parameters for defining uniform criteria for Pituitary Tumor Centers of Excellence (PTCOEs) based on expert consensus.
A. Giustina, M. M. Uygur, S. Frara, A. Barkan, N. Biermasz, P. Chanson, P. Freda, M. Gadelha, U. Kaiser, S. Lamberts, E. Laws, L. Nachtigall, V. Popović, M. Reincke, C. Strasburger, A. J. van der Lely, J. Wass, S. Melmed, F. Casanueva   +18 more
semanticscholar   +1 more source

The Hypothalamic-Pituitary-Adrenal Axis: Development, Programming Actions of Hormones, and Maternal-Fetal Interactions

Frontiers in Behavioral Neuroscience, 2021
The hypothalamic-pituitary-adrenal axis is a complex system of neuroendocrine pathways and feedback loops that function to maintain physiological homeostasis.
J. A. Sheng, Natalie J. Bales, Sage Myers, A. I. Bautista, M. Roueinfar, T. Hale, R. Handa   +6 more
semanticscholar   +1 more source

COVID-19 and the pituitary

Pituitary, 2021
Background Despite COVID-19 being identified as severe respiratory viral infection, progressively many relevant endocrine manifestations have been reported greatly contributing to the severity of the clinical presentation.
S. Frara, A. Allora, Laura Castellino, L. di Filippo, P. Loli, A. Giustina   +5 more
semanticscholar   +1 more source

A Pituitary Society update to acromegaly management guidelines

Pituitary, 2020
Guidelines and consensus statements ensure that physicians managing acromegaly patients have access to current information on evidence-based treatments to optimize outcomes.
M. Fleseriu, B. Biller, P. Freda, M. Gadelha, A. Giustina, L. Katznelson, M. Molitch, S. Samson, C. Strasburger, A. J. van der Lely, S. Melmed   +10 more
semanticscholar   +1 more source

Automatic Detection for Acromegaly Using Hand Photographs: A Deep-Learning Approach

IEEE Access, 2021
Machine learning assisted diagnosis of acromegaly from facial photographs has been proved feasible in recent years. According to our previous research, facial and limb changes exist in patients with acromegaly at early stage.
Chengbin Duan, Wenli Chen, Shun Yao, Zhigang Mao, Zongming Wang, Bin Hu, Haosen Jiao, Dimin Zhu, Yonghong Zhu, Haijun Wang   +9 more
doaj   +1 more source

Generation of isogenic and homozygous MEN1 mutant cell lines from patient-derived iPSCs using CRISPR/Cas9

Stem Cell Research, 2023
MEN1, an autosomal dominant disorder caused by mutations in the tumor suppressor gene MEN1, manifests with co-occurrence of multiple endocrine/neuroendocrine neoplasms. An iPSC line derived from an index patient carrying the mutation c.1273C>T (p.Arg465*)
Naomi Even-Zohar, Derya Metin-Armagan, Anat Ben-Shlomo, Dhruv Sareen, Shlomo Melmed   +4 more
doaj   +1 more source

Treatment of Aggressive Pituitary Adenomas: A Case-Based Narrative Review

Frontiers in Endocrinology, 2021
Management of aggressive pituitary adenomas is challenging due to a paucity of rigorous evidence supporting available treatment approaches. Recent guidelines emphasize the need to maximize standard therapies as well as the use of temozolomide and ...
Odelia Cooper, Vivien Bonert, Ning-Ai Liu, Adam N. Mamelak, Adam N. Mamelak   +4 more
doaj   +1 more source

Regulation of the Hypothalamic-Pituitary-Adrenocortical Stress Response.

Comprehensive Physiology, 2016
The hypothalamo-pituitary-adrenocortical (HPA) axis is required for stress adaptation. Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ systems to redirect energy resources to meet real or anticipated demand ...
J. Herman, J. McKlveen, Sriparna Ghosal, Brittany Kopp, Aynara C. Wulsin, Ryan A. Makinson, Jessie R Scheimann, B. Myers   +7 more
semanticscholar   +1 more source

The Clinical and Pathological Characteristics of Refractory Pituitary Adenomas: A Single Center Experience

Frontiers in Oncology, 2022
BackgroundMost of pituitary adenomas (PAs) are slow-growing benign tumors which can be cured or controlled by conventional therapies, including surgery, medical treatment or radiotherapy.
Xiaohai Liu, Xiaohai Liu, Congxin Dai, Congxin Dai, Xinjie Bao, Xinjie Bao, Kan Deng, Kan Deng, Yong Yao, Yong Yao, Ming Feng, Ming Feng, Mingchu Li, Mingchu Li, Ge Chen, Ge Chen, Renzhi Wang, Renzhi Wang   +17 more
doaj   +1 more source

How to Classify Pituitary Neuroendocrine Tumors (PitNET)s in 2020

Cancers, 2020
Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors (PitNET), are mostly benign, but may present various behaviors: invasive, “aggressive” and malignant with metastases.
J. Trouillas, M. Jaffrain-Rea, A. Vasiljevic, G. Raverot, F. Roncaroli, C. Villa   +5 more
semanticscholar   +1 more source