Results 71 to 80 of about 362,132 (303)

A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis

Indian Journal of Pathology and Microbiology, 2023
Dual pathology in the pituitary gland is a unique phenomenon. Coexistence of a pituitary adenoma with primary hypophysitis has been reported rarely with very few cases in the literature.
Sanjiban Patra, Priti Trivedi
doaj   +1 more source

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo, Ajay Madan, Christine T. Ferrara‐Cook, Deepak Dalvie, Lance Goulet, R. Scott Struthers, Alan S. Krasner   +6 more
wiley   +1 more source

Brain tumor detection using artificial convolutional neural networks [PDF]

arXiv, 2022
In this paper, a convolutional neural network (CNN) was used to classify NMR images of human brains with 4 different types of tumors: meningioma, glioma and pituitary gland tumors. During the training phase of this project, an accuracy of 100% was obtained, meanwhile, in the evaluation phase the precision was 96%.
arxiv  

Incidence of Pituitary Apoplexy and Its Risk Factors in Chinese People: A Database Study of Patients with Pituitary Adenoma

PLoS ONE, 2015
Background There are few studies of the incidence and clinical characteristics of pituitary apoplexy (PA) in pituitary adenoma patients, and the findings have been inconsistent.
Xiaoming Zhu, Yongfei Wang, Xuelan Zhao, Cuiping Jiang, Qiongyue Zhang, Wen-juan Jiang, Yan Wang, Haixia Chen, Xuefei Shou, Yao Zhao, Yiming Li, Shiqi Li, H. Ye   +12 more
semanticscholar   +1 more source

Evidence‐based management strategies for endocrine complications after pituitary adenoma surgery

Ibrain, EarlyView.
Based on the PIPOST (Population, Intervention, Professional, Outcome, Setting, and Type of Evidence) framework, evidence‐based medicine questions were developed, and a top‐down search was conducted according to the 6S model of the evidence pyramid. The literature sources were best practices, guidelines, expert consensuses, systematic reviews, meta ...
Xiaoju Miao, Zhongmin Fu, Xian Luo, Jun Wang, Zhangzhu Ren, Yuanyuan Wang, Guoping Mei, Shunwu Xiao   +7 more
wiley   +1 more source

Loss-of-function mutations in the CABLES1 gene are a novel cause of Cushing's disease. [PDF]

, 2017
The CABLES1 cell cycle regulator participates in the adrenal-pituitary negative feedback, and its expression is reduced in corticotropinomas, pituitary tumors with a largely unexplained genetic basis.
Assié, Guillaume, Balsalobre, Aurelio, Bertherat, Jérôme, Chittiboina, Prashant, Dimopoulos, Aggeliki, Drouin, Jacques, Faucz, Fabio R, Gaillard, Stephan, Gam, Ryhem, Gauthier, Yves, Hernández-Ramírez, Laura C, Kay, Denise M, Lane, John, Lodish, Maya B, Mills, James L, Neou, Mario, Pankratz, Nathan, Stratakis, Constantine A, Trivellin, Giampaolo, Valdés, Nuria, Villa, Chiara   +20 more
core   +2 more sources

A Case of Advanced Renal Cell Carcinoma With Concomitant Development of Multiple Endocrine Neoplasia Type 1 That Affected Treatment Progress With Immunotherapy

IJU Case Reports, EarlyView.
ABSTRACT Introduction Hypercalcemia is a poor prognostic factor in advanced cancer. Case Presentation A patient with advanced clear cell renal carcinoma with hypercalcemia was treated with nivolumab+ipilimumab combination therapy. Treatment was discontinued after 4 months due to renal dysfunction.
Masataka Abe, Yoshiyuki Miyaji, Seitetsu Sugiyama, Kiwami Tsurui, Hirofumi Morinaka, Mikako Kaifu, Hiroyuki Kadoya, Wataru Saito, Koji Yoshida, Kazumasa Komura   +9 more
wiley   +1 more source

Analysis of the experimental absorption spectrum of the rabbit lung and identification of its components

Journal of Biophotonics, EarlyView.
The broadband absorption coefficient spectrum of the rabbit lung was reconstructed from the absorption spectra of tissue components. The similar accumulation of melanin and lipofuscin was retrieved from the broadband baseline in the absorption coefficient spectrum, and the calculation of the absorption fold ratios for proteins, DNA and hemoglobin ...
Maria R. Pinheiro, Valery V. Tuchin, Luís M. Oliveira   +2 more
wiley   +1 more source

EGFL7 participates in regulating biological behavior of growth hormone–secreting pituitary adenomas via Notch2/DLL3 signaling pathway

Tumor Biology, 2017
Growth hormone–secreting pituitary adenoma accounts for about 20% of the third most common intracranial neoplasm—pituitary adenomas—which makes up 15% of all intracranial tumors.
Jianpeng Wang, Qian Liu, Hua Gao, Dehong Wan, Chuzhong Li, Zhaojian Li, Yazhuo Zhang   +6 more
doaj   +1 more source

TransResU-Net: Transformer based ResU-Net for Real-Time Colonoscopy Polyp Segmentation [PDF]

arXiv, 2022
Colorectal cancer (CRC) is one of the most common causes of cancer and cancer-related mortality worldwide. Performing colon cancer screening in a timely fashion is the key to early detection. Colonoscopy is the primary modality used to diagnose colon cancer.
arxiv