Interpretation of Consensus on Diagnosis and Management of Cushing's Disease: a Guideline Update of the International Pituitary Society——Diagnosis [PDF]
Cushing disease, the most common cause of endogenous Cushing's syndrome characterized by hypercortisolemia, is a clinical syndrome caused by adrenocorticotropic hormone (ACTH) ——secreting pituitary adenomas.
Huiwen TAN, Yu TANG, Yerong YU, Jianwei LI, Jiaqi LI, Zhenmei AN, Chun WANG, Yi WEI
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Interpretation of Consensus on Diagnosis and Management of Cushing's Disease: a Guideline Update from the Pituitary Society——Medical Therapies [PDF]
Cushing's disease, the most common cause of endogenous Cushing's syndrome, is hypercortisolemia caused by adrenocorticotropic hormone-secreting pituitary adenoma.
TANG Yu, TAN Huiwen, LI Jianwei, YU Yerong
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Genetics of Pituitary Adenomas [PDF]
Clinically relevant pituitary tumors presenting with altered hormonal secretion or mass effect represent a significant proportion of patients in endocrinology clinics. However, in recent years, these patients are also referred to clinical genetic services due to possible germline mutations causing syndromic or isolated pituitary adenomas. While somatic
Bogusławska, Anna +2 more
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The invasiveness and high proliferation rate of growth hormone-secreting pituitary adenomas (GHPAs) are closely related to poor prognosis in patients.
Yin Zhang +10 more
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Interpretation of ESE Clinical Practice Guideline on Functioning and Non-functioning Pituitary Adenomas in Pregnancy [PDF]
Pituitary adenomas usually cause damage to the gonadal axis, leading to a decrease in fertility in female patients. As pituitary gland enlarges during pregnancy, the hormone secretion of the gonadal axis changes accordingly. Therefore, it is particularly
DENG Chenqian, BAN Jiangli, CHEN Shuchun
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Pituitary tumors and the risk of other malignancies: is the relationship coincidental or causal?
Pituitary adenomas are benign neoplasms of the pituitary. The most prevalent are prolactinomas and non-functioning pituitary adenomas, followed by growth hormone-and ACTH-secreting adenomas.
Sandra Pekic +2 more
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Contribution of PROP1 in the pathogenesis of Cushing’s disease: A preliminary study
Prophet of Pit1 (PROP1) is the pituitary specific transcription factor which was cloned as an upstream regulator of PIT1. Cushing’s disease is caused by corticotroph adenomas which does not belong to the PIT1 lineage.
Noriyoshi Takebe +6 more
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Research advances on the immune research and prospect of immunotherapy in pituitary adenomas
Background Pituitary adenomas are one type of intracranial tumor, which can be divided into microadenoma (≤ 1 cm), macroadenoma (> 1 cm), and giant adenoma (≥ 4 cm) according to their diametral sizes.
Ding Nie +7 more
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The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas
Human pituitary adenomas are one of the most common intracranial neoplasms. Although most of these tumors are benign and can be treated medically or by transsphenoidal surgery, a subset of these tumors are fast-growing, aggressive, recur, and remain a ...
Zhiyu Xi +10 more
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TERT Expression in Pituitary Adenomas [PDF]
Objective: Although pituitary adenomas have benign histomorphological features, some of them may present in an aggressive manner. To predict the behaviour of these tumours, telomerase reverse transcriptase (TERT) activity in pituitary adenomas has been ...
Nuray CAN +10 more
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