Results 21 to 30 of about 18,298 (190)

Pituitary tumours — a large retrospective single-centre study of over 2300 cases. Experience of a tertiary reference centre

Endokrynologia Polska, 2020
INTRODUCTION: Pituitary adenomas (PAs), also known as a pituitary neuroendocrine tumours (PitNET), are usually benign tumours of the anterior lobe of the pituitary gland and account for the third most common intracranial neoplasm. The most common type of
Beata Rak, Maria Maksymowicz, Tomasz M. Grzywa, Emir Sajjad, Monika Pękul, Paweł Włodarski, Grzegorz Zieliński   +6 more
doaj   +1 more source

Up-regulation of sex-determining region Y-box 9 (SOX9) in growth hormone-secreting pituitary adenomas

BMC Endocrine Disorders, 2021
Background Pituitary adenomas are benign brain tumors that cause considerable morbidity and neurological symptoms. SOX9 as a regulatory transcriptional mediator affects normal and tumor cell growth with an undefined role in pituitary adenomas ...
Farzad Izak Shirian, Mohammad Ghorbani, Mohammad E. Khamseh, Mehrnaz Imani, Mahshid Panahi, Alimohammad Alimohammadi, Mitra Nourbakhsh, Vahid Salimi, Masoumeh Tavakoli-Yaraki   +8 more
doaj   +1 more source

High Expression of Somatostatin Receptors 2A, 3, and 5 in Corticotroph Pituitary Adenoma

International Journal of Endocrinology, 2018
The development of somatostatin analogs for the treatment of pituitary Cushing’s disease has been based on somatostatin receptor expression analyses of small cohorts of pituitary adenomas.
Felix Behling, Jürgen Honegger, Marco Skardelly, Irina Gepfner-Tuma, Ghazaleh Tabatabai, Marcos Tatagiba, Jens Schittenhelm   +6 more
doaj   +1 more source

CLINICAL AND MORPHOLOGICAL RESEARCH INTO THE ROLE OF THE TRANSCRIPTION FACTOR NEUROD1 IN VARIOUS TYPES OF PITUITARY ADENOMAS

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
The role of transcription factors in the pathogenesis of pituitary adenomas is extremely controversial.The aim of the study was to investigate the role of the transcription factor Neuro D1 in various types of pituitary adenomas.Materials and methods.
O. M. Raspopova, L. B. Mitrofanova, B. E. Galkovsky, U. A. Tsoy, U. N. Grineva, A. A. Palcev, V. R. Rodichkina   +6 more
doaj   +1 more source

Pituitary Adenomas

Topics in Magnetic Resonance Imaging, 2005
Pituitary adenomas are by far the most common sellar tumor and magnetic resonance imaging is the modality of choice for their detection and characterization. However, most of these neoplasms are asymptomatic and frequently incidentally visualized.
openaire   +3 more sources

A Rare Corticotroph-Secreting Tumor with Coexisting Prolactin and Growth Hormone Staining Cells

Case Reports in Endocrinology, 2012
Pituitary adenomas can express and secrete different hormones. Expression of pituitary hormones in nonneoplastic pituitary cells is regulated by different transcription factors. Some pituitary adenomas show plurihormonal expression.
Subramanian Kannan, Susan M. Staugaitis, Robert J. Weil, Betul Hatipoglu   +3 more
doaj   +1 more source

Change in the pituitary stalk deviation angle after transsphenoidal surgery can predict the development of diabetes insipidus for pituitary adenomas

Endocrine Connections, 2022
Purpose: We aimed to assess the factors influencing the development of d iabetes insipidus after transsphenoidal surgery for pituitary adenomas. Methods: A retrospective analysis was conducted on the clinical data of patients with pituitary adenomas ...
Liang Xue, Jianwu Wu, Jie Chen, Yongkai Yang   +3 more
doaj   +1 more source

Cholesterol-activated stress granules reduce the membrane localization of DRD2 and promote prolactinoma dopamine agonists resistance

Acta Neuropathologica Communications
Prolactinoma is the most prevalent pituitary neuroendocrine tumor and dopamine agonists (DAs) targeting dopamine D2 receptor (DRD2) are recommended as the first-line treatment. However, varying degrees of DA resistance limit patient benefit.
Yuyang Peng, Huachun Yin, Xiangdong Pei, Yuan Zhang, Chengcheng Wang, Xin Zheng, Hong Liang, Hui Yang, Song Li   +8 more
doaj   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Clinical Evaluation of Non-functional Invasive Hypophysis Adenomas

Sudan Journal of Medical Sciences, 2020
Background: There are ongoing studies to predetermine non-functional invasive pituitary adenomas that may show aggressive behavior. Our aim is to discuss whether there is a relationship between the immunohistochemical presence of GH, FSH, LH, PRL, ACTH ...
Feyzi Gokosmanoglu, Ceyhun Varim, Kenan Evren Oztop   +2 more
doaj   +1 more source