Results 11 to 20 of about 18,298 (190)

Giant pituitary adenoma [PDF]

BMJ Case Reports, 2014
A healthy 68-year-old man presented in the emergency room with a sudden episode of headache and vomiting together with disequilibrium and crural paresis. The laboratory evaluation revealed hyponatraemia (Na+115 mEq/L). Head MRI demonstrated a giant 40×25×31 mm pituitary lesion (figures 1 and 2). Laboratory studies revealed growth hormone (GH) 0.1 ng/mL
Leão, R, Baptista, J, Vaz Ribeiro, J
openaire   +3 more sources

SCP2-mediated cholesterol membrane trafficking promotes the growth of pituitary adenomas via Hedgehog signaling activation

Journal of Experimental & Clinical Cancer Research, 2019
Background Metabolic reprogramming is an important characteristic of tumors. In the progression of pituitary adenomas (PA), abnormal glucose metabolism has been confirmed by us before. However, whether cholesterol metabolism is involved in the process of
Xiao Ding, Kexia Fan, Jintao Hu, Zhenle Zang, Shunli Zhang, Yin Zhang, Zhichao Lin, Xiangdong Pei, Xin Zheng, Feng Zhu, Hui Yang, Song Li   +11 more
doaj   +1 more source

Evaluation and Current Clinical Progress of Invasiveness in Postoperative Residual Regrowth and Recurrence of Pituitary Adenoma

Zhongliu Fangzhi Yanjiu, 2022
Pituitary adenoma is one common type of intracranial tumors, accounting for about 10% of intracranial tumors. Although pituitary adenomas are benign tumors, the complete resection and recurrence prevention remain challengeable due to aggressive growth of
LEI Ting, WAN Xueyan, LIU Huiyong, LU Liang, CHEN Juan, SHU Kai   +5 more
doaj   +1 more source

Risk factors of recurrent non-functioning pituitary adenomas in patients with growth hormone deficiency

Mìžnarodnij Endokrinologìčnij Žurnal, 2019
Background. Nowadays, a search for diagnostically significant markers of aggressiveness of non­functioning pituitary adenomas remains relevant for further prognosis in the postoperative period.
Yu.M. Urmanova, M.Yu. Shakirova, N.T. Rikhsieva, F.S. Khodgaeva   +3 more
doaj   +1 more source

Lineage-specific restraint of pituitary gonadotroph cell adenoma growth. [PDF]

PLoS ONE, 2011
Although pituitary adenomas are usually benign, unique trophic mechanisms restraining cell proliferation are unclear. As GH-secreting adenomas are associated with p53/p21-dependent senescence, we tested mechanisms constraining non-functioning pituitary ...
Vera Chesnokova, Svetlana Zonis, Cuiqi Zhou, Anat Ben-Shlomo, Kolja Wawrowsky, Yoel Toledano, Yunguang Tong, Kalman Kovacs, Bernd Scheithauer, Shlomo Melmed   +9 more
doaj   +1 more source

Lactate dehydrogenase A promotes the invasion and proliferation of pituitary adenoma

Scientific Reports, 2017
Lactate dehydrogenase A (LDHA) has been reported to be involved in the initiation and progression of tumors. However, the potential role of LDHA in pituitary adenoma (PA) remains unknown.
Jiayin An, Yin Zhang, Jiaojiang He, Zhenle Zang, Zheng Zhou, Xiangdong Pei, Xin Zheng, Weihua Zhang, Hui Yang, Song Li   +9 more
doaj   +1 more source

Endoscopic endonasal transsphenoidal surgery: predictors for disease control in a consecutive series of pituitary adenomas

The Egyptian Journal of Otolaryngology, 2016
En Abstract Background Endoscopic endonasal transsphenoidal surgery for pituitary lesions has been predestined and evolved since its incipient description.
Mostafa Ismail, Balegh Abdelhak, Jean D’Haens, Olaf Michel   +3 more
doaj   +1 more source

The Epigenomics of Pituitary Adenoma [PDF]

Frontiers in Endocrinology, 2019
Background: The vast majority of pituitary tumors are benign and behave accordingly; however, a fraction are invasive and are more aggressive, with a very small fraction being frankly malignant. The cellular pathways that drive transformation in pituitary neoplasms are poorly characterized, and current classification methods are not reliable correlates
Blake M. Hauser, Ashley Lau, Saksham Gupta, Wenya Linda Bi, Ian F. Dunn   +4 more
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Pituitary Adenomas: From Diagnosis to Therapeutics

Biomedicines, 2021
Pituitary adenomas are tumors that arise in the anterior pituitary gland. They are the third most common cause of central nervous system (CNS) tumors among adults.
Samridhi Banskota, David C. Adamson
doaj   +1 more source

Pituitary adenoma surgery survey: neurosurgical centers and pituitary adenomas

Brain and Spine, 2022
Objective. Pituitary adenoma surgery has evolved rapidly in recent decades. This study aims to determine current practice across a wide range of European neurosurgical centers. Methods. A list of eligible departments performing pituitary adenoma surgery was created. The survey consisted of 58 questions.
David Netuka, Andre Grotenhuis, Nicolas Foroglou, Francesco Zenga, Sebastien Froehlich, Florian Ringel, Nicolas Sampron, Nick Thomas, Martin Komarc, Martin Majovsky   +9 more
openaire   +6 more sources