Results 71 to 80 of about 108,268 (286)

Pituitary Stalk Germ Cell Tumors: Retrospective Case Series and Literature Review

open access: yesInternational Journal of Endocrinology, 2022
Objective. Intracranial germ cell tumors with isolated pituitary stalk involvement are rare. Early recognition and long-term monitoring deserve further exploration. Methods.
Han Chen, Ming Ni, Yun Xu, Li-Yong Zhong
doaj   +1 more source

GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation

open access: yesAdvanced Science, EarlyView.
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim   +9 more
wiley   +1 more source

Advances in Medical Devices for Augmented Acupuncture Therapy

open access: yesAdvanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai   +7 more
wiley   +1 more source

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

open access: yesAdvanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu   +7 more
wiley   +1 more source

Diagnosis of pituitary disease

open access: yesMedicine, 2005
Abstract Sited at the base of the brain, the pituitary gland, comprising two lobes (anterior and posterior), is linked by a stalk to the hypothalamus and median eminence, which regulate its function. Different cell types in the anterior pituitary secrete growth hormone, prolactin, adrenocorticotrophic hormone, thyroid-stimulating hormone, luteinizing ...
openaire   +2 more sources

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

open access: yesAdvanced Science, EarlyView.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu   +12 more
wiley   +1 more source

Investigation Of Pituitary Disease

open access: yes, 2018
The close relationship between the upper respiratory tract (nose and paranasal sinuses) and the lower respiratory tract (tracheobronchial tree) is something that is manifestly observed by all practising rhinologists. There is strong epidemiological evidence both from cross-sectional and longitudinal studies that rhinitis and asthma are related.
Sathyapalan, Thozhukat   +1 more
openaire   +3 more sources

Bioinspired Prolactin Pulse Release from Responsive Microneedles for Inhibiting Fatty Liver Formation

open access: yesAdvanced Science, EarlyView.
Inspired by the prolactin secretion profile under normal physiological conditions, biomimetic prolactin‐releasing microneedles are designed. Under the control of near infrared (NIR), these responsive microneedles facilitate pulsed release of prolactin to inhibit fatty liver formation.
Hongli Yin   +6 more
wiley   +1 more source

Comparative Single‐Cell Transcriptomic Landscape Reveals the Regulatory Mechanisms of Lactation during Selective Breeding in Asian Water Buffalo

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of river and swamp buffalo, encompassing 12 tissues and 397,011 cells, is constructed. Differential expression analyses identify metabolic and secretory tissues and cell types that mediate the divergence of milk production.
Dongmei Dai   +13 more
wiley   +1 more source

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