Results 131 to 140 of about 99,631 (261)
The Journal of Pathology, EarlyView.Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim +9 more
wiley +1 more source
Consensus Pituitary Atlas, a scalable resource for annotation, novel marker discovery, and analyses in mouse pituitary gland research. [PDF]
Cell RepKövér B +15 more
europepmc +1 more source
Identification of Novel Interacting Proteins of FUZ and GPR161
PROTEOMICS, EarlyView.ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar +3 more
wiley +1 more source
Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use
The Prostate, EarlyView.ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley +1 more source
Integrin αvβ6 Expression in the Human Pituitary Gland and Pituitary Neuroendocrine Tumors: Immunohistochemical Characterization with Potential Relevance to αvβ6 PET/CT Pituitary Uptake and Theranostic Implications. [PDF]
BiomoleculesTuffaha M +3 more
europepmc +1 more source
Discussion on the Surgery of the Pituitary Gland [PDF]
Proceedings of the Royal Society of Medicine, 1920 openaire +4 more sources
Phytotherapy Research, EarlyView.Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli +6 more
wiley +1 more source
Rheumatology &Autoimmunity, EarlyView.A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa +3 more
wiley +1 more source
MRI findings of an incidental ectopic posterior pituitary gland in an adult: Case report and review of T1 hyperintense lesions in the literature. [PDF]
Radiol Case RepHashem S, Murhega RB, Migabo PA.
europepmc +1 more source
Sleep Research, EarlyView.Abstract Background The red blood cell distribution width‐to‐albumin ratio (RAR) is a novel composite biomarker of inflammation and nutritional status, yet its association with insomnia and underlying mechanisms remain poorly understood. Objective To investigate the association between the RAR and insomnia in two independent cohorts, comprising a ...
Jingying Ma +7 more
wiley +1 more source