Results 121 to 130 of about 162,638 (311)

Nutritional priorities to support GLP‐1 therapy for obesity: A joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society

Obesity, EarlyView.
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian, Monica Agarwal, Monica Aggarwal, Lydia Alexander, Caroline M. Apovian, Shagun Bindlish, Jonathan Bonnet, W. Scott Butsch, Sandra Christensen, Eugenia Gianos, Mahima Gulati, Alka Gupta, Debbie Horn, Ryan M. Kane, Jasdeep Saluja, Deepa Sannidhi, Fatima Cody Stanford, Emily A. Callahan   +17 more
wiley   +1 more source

Wilms Tumor in Children with AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 10–15% of children with Wilms tumor (WT) have predisposing genetic syndromes. Somatic mutations are frequently identified; however, germline pathogenic variants in AMER1 are much less prevalent and are associated with osteopathia striata with cranial sclerosis (OSCS).
Insiyah Campwala, Jaclyn Schienda, Andrew J. Murphy, Basil Hashimi, Taylor Perry, Nicholas Cost, Junne Kamihara, Elizabeth A. Mullen, Teresa Santiago, Marcus M. Malek   +9 more
wiley   +1 more source

Comprehensive Review of the Impact of Maternal Stress on Fetal Development

Pediatric Discovery, EarlyView.
ABSTRACT Maternal stress impacts millions of pregnant women across the globe each year and refers to mental or psychological stress that occurs during the prenatal period. Although it remains known that maternal stress can negatively impact maternal health, the downstream effects of stress on fetal and infant development in the long‐term are unclear ...
Divya Tadanki, Pranitha S. Kaza, Elliana Meisinger, Ariana Syed, Asha Johnson, Garen Bainbridge, Michelle Cho, Chikaima Anigbogu, Gargi Gupta   +8 more
wiley   +1 more source

Concomitant Pituitary Apoplexy and Acute Fatty Liver of Pregnancy Complicated With Disseminated Intravascular Coagulation

AACE Clinical Case Reports, 2015
: Objective: Pituitary complications during delivery are relatively rare in developed countries. In this case report we describe a case of panhypopituitarism during pregnancy with concomitant acute liver failure.Methods: We present the case of a pregnant
Umang Barvalia, MD, Myrto Eliades, MD, Lina Melhem, MD   +2 more
doaj  

Modeling Iodine Deficiency [PDF]

arXiv
This paper presents a four-unit, four-component mathematical model of iodine metabolism and its impact on thyroid hormone levels in the body. We focus on the relationships between iodine (I-), triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) through the mixer, thyroid, sensor (pituitary gland), and metabolism. Iodine plays a
arxiv  

Multi-Task Gaussian Processes and Dilated Convolutional Networks for Reconstruction of Reproductive Hormonal Dynamics [PDF]

arXiv, 2019
We present an end-to-end statistical framework for personalized, accurate, and minimally invasive modeling of female reproductive hormonal patterns. Reconstructing and forecasting the evolution of hormonal dynamics is a challenging task, but a critical one to improve general understanding of the menstrual cycle and personalized detection of potential ...
arxiv  

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

Small, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun, Nicholas Andrikopoulos, Guofang Zhang, Yuying Liu, Xiufang Liang, Dongjie Li, Xiaoman Suo, Yue Wang, Yuhuan Li, Chuang Wang, Yang Li, Pu Chun Ke, Feng Ding   +12 more
wiley   +1 more source

Towards Personalized Modeling of the Female Hormonal Cycle: Experiments with Mechanistic Models and Gaussian Processes [PDF]

arXiv, 2017
In this paper, we introduce a novel task for machine learning in healthcare, namely personalized modeling of the female hormonal cycle. The motivation for this work is to model the hormonal cycle and predict its phases in time, both for healthy individuals and for those with disorders of the reproductive system. Because there are individual differences
arxiv  

Emerging trends in the management of non‐obstructive azoospermia

UroPrecision, EarlyView.
Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad, Mohamed Alkabeer, Dina Abdelmonim, Sameh Fayek GamalElDin, Mohamed Wael Ragab   +4 more
wiley   +1 more source

Isolated asthenozoospermia: What should we know? A narrative review of literature

UroPrecision, EarlyView.
ABSTRACT Male infertility contributes to 20%–70% of infertile couple cases worldwide. One of the key challenges in this area is asthenozoospermia or reduced sperm motility. A particular subset, known as isolated asthenozoospermia (iASZ), in which low motility occurs without abnormalities in sperm count or shape, often goes unnoticed and is not well ...
Ahmed Eissa, Khaled Almekaty, Ahmed Zoeir, Hussein Mamdoh, Ayman Mousa, Mohammed Abou‐elenein, Tarek Gameel, Maged Ragab   +7 more
wiley   +1 more source