Results 201 to 210 of about 62,335 (310)

A mini‐review of chronic suppression of the hypothalamic–pituitary–adrenal axis in animals with P‐glycoprotein deficiency

open access: yesJournal of Small Animal Practice, EarlyView.
This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley   +1 more source

In the End: Associations Between Sleep Disturbance and Functional Impairment in Fibromyalgia—A Path Analysis Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Fibromyalgia is a chronic pain condition characterised by widespread pain, sleep disturbances and mood disorders, often leading to significant functional impairment. Although sleep problems are recognised as important contributors to fibromyalgia symptoms, the mechanisms linking sleep disturbances, psychological factors and functional ...
Kristoffer Bothelius   +2 more
wiley   +1 more source

Increased p‐Tau181 Levels After Overnight Wakefulness Are Associated With Neuroticism in Young Women

open access: yesJournal of Sleep Research, EarlyView.
Overnight wakefulness, mimicking night shift conditions, impaired morning vigilance in healthy, reproductive‐aged women, regardless of estradiol or neuroticism. However, the overnight wakefulness‐related rise in the Alzheimer's disease blood biomarker p‐Tau181 was greater in women with higher neuroticism, suggesting that neurobiological vulnerability ...
Diana A. Nôga   +14 more
wiley   +1 more source

Dynamics of anterior pituitary function in the acute phase of traumatic brain injury: a prospective cohort. [PDF]

open access: yesCrit Care Sci
Cáceres E   +8 more
europepmc   +1 more source

Complex demographic, developmental, fitness, and physiological responses of larval eastern hellbenders to elevated water conductivity

open access: yesJournal of Zoology, EarlyView.
Here we explore the effects of elevated water conductivity on larval eastern hellbenders (Cryptobranchus a. alleganiensis), both lethal and sublethal. We found that elevated water conductivity significantly impacts both survival and morphology, though it has limited effects on locomotor performance, stress physiology, and oxidative stress.
S. C. Mathes   +6 more
wiley   +1 more source

The Efficacy of Pharmacotherapy Intervention on Anthropometric Outcomes in Survivors of Childhood Brain Tumors: An Updated Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart   +11 more
wiley   +1 more source

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