Results 221 to 230 of about 64,206 (312)

Corticotropin‐Releasing Hormone (CRH) in Murine Narcolepsy: What Do Genetic and Immune Models Tell Us?

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou   +7 more
wiley   +1 more source

Unifying regulatory motifs in endocrine circuits. [PDF]

open access: yesNat Commun
Raz M   +7 more
europepmc   +1 more source

Sleep and Rhythmic Profile After Pineal Gland Removal in Humans

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Melatonin, a hormone produced by the pineal gland, is classically described as a central circadian modulator. However, the impact of its absence on circadian rhythmicity in humans remains poorly understood. Pinealectomised patients, in whom melatonin secretion is chronically suppressed, represent a valuable clinical model to investigate the ...
Renata de Andrade Prado Gobetti   +7 more
wiley   +1 more source

Biological poisons targeting the pituitary gland: insights across the five kingdoms. [PDF]

open access: yesFront Endocrinol (Lausanne)
Sanchis-Pascual D   +6 more
europepmc   +1 more source

In the End: Associations Between Sleep Disturbance and Functional Impairment in Fibromyalgia—A Path Analysis Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Fibromyalgia is a chronic pain condition characterised by widespread pain, sleep disturbances and mood disorders, often leading to significant functional impairment. Although sleep problems are recognised as important contributors to fibromyalgia symptoms, the mechanisms linking sleep disturbances, psychological factors and functional ...
Kristoffer Bothelius   +2 more
wiley   +1 more source

Increased p‐Tau181 Levels After Overnight Wakefulness Are Associated With Neuroticism in Young Women

open access: yesJournal of Sleep Research, EarlyView.
Overnight wakefulness, mimicking night shift conditions, impaired morning vigilance in healthy, reproductive‐aged women, regardless of estradiol or neuroticism. However, the overnight wakefulness‐related rise in the Alzheimer's disease blood biomarker p‐Tau181 was greater in women with higher neuroticism, suggesting that neurobiological vulnerability ...
Diana A. Nôga   +14 more
wiley   +1 more source

Complex demographic, developmental, fitness, and physiological responses of larval eastern hellbenders to elevated water conductivity

open access: yesJournal of Zoology, EarlyView.
Here we explore the effects of elevated water conductivity on larval eastern hellbenders (Cryptobranchus a. alleganiensis), both lethal and sublethal. We found that elevated water conductivity significantly impacts both survival and morphology, though it has limited effects on locomotor performance, stress physiology, and oxidative stress.
S. C. Mathes   +6 more
wiley   +1 more source

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