Results 221 to 230 of about 64,206 (312)
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou +7 more
wiley +1 more source
Unifying regulatory motifs in endocrine circuits. [PDF]
Raz M +7 more
europepmc +1 more source
Sleep and Rhythmic Profile After Pineal Gland Removal in Humans
ABSTRACT Melatonin, a hormone produced by the pineal gland, is classically described as a central circadian modulator. However, the impact of its absence on circadian rhythmicity in humans remains poorly understood. Pinealectomised patients, in whom melatonin secretion is chronically suppressed, represent a valuable clinical model to investigate the ...
Renata de Andrade Prado Gobetti +7 more
wiley +1 more source
Biological poisons targeting the pituitary gland: insights across the five kingdoms. [PDF]
Sanchis-Pascual D +6 more
europepmc +1 more source
ABSTRACT Fibromyalgia is a chronic pain condition characterised by widespread pain, sleep disturbances and mood disorders, often leading to significant functional impairment. Although sleep problems are recognised as important contributors to fibromyalgia symptoms, the mechanisms linking sleep disturbances, psychological factors and functional ...
Kristoffer Bothelius +2 more
wiley +1 more source
Pituitary Neuroendocrine Tumors Extending Primarily Below the Sella and into the Clivus: A Distinct Growth Pattern with Specific Challenges. [PDF]
Sannwald LW +7 more
europepmc +1 more source
Increased p‐Tau181 Levels After Overnight Wakefulness Are Associated With Neuroticism in Young Women
Overnight wakefulness, mimicking night shift conditions, impaired morning vigilance in healthy, reproductive‐aged women, regardless of estradiol or neuroticism. However, the overnight wakefulness‐related rise in the Alzheimer's disease blood biomarker p‐Tau181 was greater in women with higher neuroticism, suggesting that neurobiological vulnerability ...
Diana A. Nôga +14 more
wiley +1 more source
Comparison of oral versus intravenous glucose exposure on plasma growth hormone levels: a crossover study in healthy volunteers. [PDF]
Vinten AK +4 more
europepmc +1 more source
Here we explore the effects of elevated water conductivity on larval eastern hellbenders (Cryptobranchus a. alleganiensis), both lethal and sublethal. We found that elevated water conductivity significantly impacts both survival and morphology, though it has limited effects on locomotor performance, stress physiology, and oxidative stress.
S. C. Mathes +6 more
wiley +1 more source

