PLoS ONE, 2022 IntroductionObesity is characterized by elevated lipids, insulin resistance and relative hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy complications and birth defects. We termed this phenotype 'Reprometabolic Syndrome'
Rosemary McDonald +6 more
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Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells
Nature Communications, 2016 It is difficult to generate functional human anterior pituitary tissues in vitro. Here, Ozone et al. generate human anterior pituitary from embryonic stem cells by recapitulating in vivodevelopment, and demonstrate this tissue secretes hormones and ...
Chikafumi Ozone +8 more
doaj +1 more source
Pituitary stalk interruption syndrome presenting in a euthyroid adult with short stature
Radiology Case Reports, 2018 Pituitary stalk interruption syndrome (PSIS) is a distinct and rare clinical entity responsible for congenital hypopituitarism resulting in deficiency of pituitary hormones with deficiency of the growth hormone (100%) and gonadotropins (97.2%) being its ...
Atif Nawaz, MBBS, FCPS-I, FRCR-I +2 more
doaj +1 more source
Electrolyte Imbalance in Patients with Sheehan's Syndrome [PDF]
Endocrinology and Metabolism, 2015 BackgroundWe investigated the prevalence of electrolyte imbalance and the relationship between serum electrolyte and anterior pituitary hormone levels in patients with Sheehan's syndrome.MethodsIn a retrospective study, we investigated 78 patients with ...
Chur Hoan Lim +7 more
doaj +1 more source
The effect of acute heat exposure on rat pituitary corticotroph activation: the role of vasopressin.
Folia Histochemica et Cytobiologica, 2011 The increased ambient temperature affects the function of hypothalamic-pituitary-adrenal (HPA) axis. Since the correlation among vasopressin (VP), adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses to various stressors have been long ...
Sinisa Djurasevic +8 more
doaj +1 more source
Gene expression patterns in anterior pituitary associated with quantitative measure of oestrous behaviour in dairy cows [PDF]
, 2010 Intensive selection for high milk yield in dairy cows has raised production levels substantially but at the cost of reduced fertility, which manifests in different ways including reduced expression of oestrous behaviour.
Beerda, B. +8 more
core +2 more sources
ZBTB20 is required for anterior pituitary development and lactotrope specification
Nature Communications, 2016 The pituitary is a complex structure with the anterior lobe containing five specialized cell types secreting different hormones. Here Cao et al. unravel a role for ZBTB20 in pituitary development and specifically in lactrotrope specification.
Dongmei Cao +16 more
doaj +1 more source
Successful twin pregnancy in panhypopituitarism
Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2015 Panhypopituitarism is characterized by inadequate or absent production of anterior pituitary hormones. This involves hypofunction of most of the major endocrine functions that affect fertility and reproduction.
R. D. Jeewantha +3 more
doaj +1 more source
Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]
, 2004 Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C. +2 more
core +1 more source
Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis
Acta Neuropathologica Communications, 2021 Pituitary neuroendocrine tumors (PitNETs) are common, generally benign tumors with complex clinical characteristics related to hormone hypersecretion and/or growing sellar tumor mass.
Abdellah Tebani +9 more
doaj +1 more source