Results 61 to 70 of about 62,335 (310)
Unmasking the pituitary shadow 11 years postpartum: A case report of late-stage Sheehan's syndrome
Sheehan's syndrome (SS) is a rare but significant condition that occurs as a result of postpartum pituitary gland infarction, typically following severe blood loss or hypotension during or after childbirth.
Oumaima Mesbah +5 more
doaj +1 more source
Hypo-pituitarism results from impaired production of one or more of anterior pituitary trophic hormones. A rare cause of hypo-pituitarism is pituitary stalk transection syndrome.
Chinmay Kulkarni +4 more
doaj +1 more source
Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]
BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J +6 more
core +3 more sources
A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu +6 more
wiley +1 more source
The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model
Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins +104 more
wiley +1 more source
An injectable CNC–PNIPAM hydrogel is developed for intrauterine co‐delivery of levonorgestrel and botropase. This platform reprograms uterine natural killer cells toward an immune–tolerant phenotype and enhances endometrial receptivity marker expression. The results demonstrate a promising strategy to counteract endometriosis–associated infertility and
Zhou Liang +9 more
wiley +1 more source
Influence of mirtazapine on salivary cortisol in depressed patients [PDF]
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C. +3 more
core +1 more source
Thyreotropic Hormone of Anterior Pituitary
SummaryWe have reported the physiological effects of a highly purified extract of the anterior pituitary containing the thyreotropic hormone, which gives complete replacement therapy in the hypo-physectomized rat and also produces a hyperplasia of the thyroid with hyperthyroidism in both the rat and the guinea pig.
E. M. Anderson, J. B. Collip
openaire +1 more source
This study was to evaluate the role of GH in lipolysis and insulin sensitivity in bovine adipocytes and clarify the underlying mechanism. Our findings demonstrate that GH activates ERK/HSL signaling pathway, promotes lipolysis, and impairs insulin sensitivity in bovine adipocytes.
Xinxing Gao +10 more
wiley +1 more source
Amygdalin is represented in the family Rosacea more precisely in apricot kernels and almonds. There are a lot of components such as trace elements, vitamins, carbohydrates, organic acids, esters, phenols, terpenoids, except cyanogenic glycoside in the ...
Katarína Michalcová +8 more
doaj

