Results 121 to 130 of about 68,420 (313)

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

A CASE OF INFANTILISM ASSOCIATED WITH PITUITARY NEOPLASM [PDF]

Archives of Internal Medicine, 1913
Illness depending on pituitary disturbances is becoming more frequently recognized. The case of infantilism here reported is presented as an example of an interesting condition worthy of addition to the records of pituitary disorders. CASE REPORT History .—H.
openaire   +1 more source

Evaluating Brief Behavioural Activation for depression in adolescents with acquired brain injury using a single‐case experimental design

JCPP Advances, EarlyView.
Abstract Background Adolescents who have had an acquired brain injury (ABI) commonly experience depression. Brief Behavioural Activation (Brief BA) is a successful, values‐based intervention for managing depression in neurotypical adolescents. This study investigated the effectiveness of Brief BA, using a single‐case experimental design, with ...
Conor R. O’Brien, Jenny Limond, Shirley Reynolds, Laura Pass, Anna‐Lynne R. Adlam   +4 more
wiley   +1 more source

Relevance of somatostatin receptors and other peptide receptors in pathology [PDF]

, 2018
Receptors for regulatory peptides can be overexpressed by several diseases, in particular by neoplasms. This review summarizes the current status of knowledge in this field, on the basis of in vitro receptor studies and with emphasis on receptors for ...
Reubi, Jean
core  

Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis

The Laryngoscope, EarlyView.
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua, Yong Hoe Chan, Woei Shyang Loh, De Yun Wang   +3 more
wiley   +1 more source

Leiomyomatoid angiomatous neuroendocrine tumor (LANT) of the pituitary: a distinctive biphasic neoplasm with primitive secretory phenotype and smooth muscle-rich stroma [PDF]

, 2018
We describe a hitherto undocumented variant of dimorphic pituitary neoplasm composed of an admixture of neurosecretory cells and profuse leiomyomatous stroma around intratumoral vessels.
Christ, Emanuel, Kappeler, Andreas, Sahli, Rahel, Seiler, Rolf, Vajtai, Istvan   +4 more
core  

The Application of Telemedicine in Surgery

Med Research, EarlyView.
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang, Chang Liu, Xue Sun, Yiting Wang, Minghui Zhao, Shuya Jiang, Haoling Zhang, Wangzheqi Zhang, Wenwen Shi   +8 more
wiley   +1 more source

FSH-producing pituitary neuroendocrine tumor as a cause of ovarian hyperstimulation syndrome

Endocrinology, Diabetes & Metabolism Case Reports
Functioning gonadotroph tumors are rare neoplasms that can cause ovarian hyperstimulation syndrome (OHSS) in women of reproductive age. Here, we present a case of a follicle-stimulating hormone (FSH)-producing pituitary neuroendocrine tumor (PitNET) with
Takuya Kitamura, Kazutaka Nanba, Kento Doi, Naoya Kishimoto, Kaoru Abiko, Ryo Kuwahara, Koki Moriyoshi, Naoko Inoshita, Tetsuya Tagami   +8 more
doaj   +1 more source

Endocrine Disorders as a Contributory Factor to Neoplasia in SJL/J Mice [PDF]

, 2017
We studied the endocrine status of SJL/J mice. Light and electron microscopy revealed that the adenohypophyses of both sexes became progressively infiltrated with an abnormal number of gonadotropinproducing cells that probably secreted large amounts of ...
Bianchi, E., Bree, M., Haran-Ghera, N., Meshorer, A., Müller, J., Pierpaoli, W.   +5 more
core  

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source