Results 131 to 140 of about 828,117 (319)

Decreased Vision and Junctional Scotoma from Pituicytoma

Case Reports in Ophthalmology, 2012
Pituicytomas are rare neoplasms of the sellar region. We report a case of vision loss and a junctional scotoma in a 43-year-old woman caused by compression of the optic chiasm by a pituitary tumor.
Nancy Huynh, Anat O. Stemmer-Rachamimov, Brooke Swearingen, Dean M. Cestari   +3 more
doaj   +1 more source

Prevalence of neoplasms in patients with acromegaly – the need for a national registry [PDF]

, 2018
Introduction Acromegaly is an endocrine disorder caused predominantly by pituitary adenoma leading to autonomic oversecretion of growth hormone and secondary elevation of insulin-like growth factor 1 (IGF-1).
Jolanta Kowalczyk-Bołtuć, Kowalczyk-Bołtuć, J., Marcin Lewicki, Obel, E., Matyjaszek-Matuszek, B., Agata Smoleń, Beata Matyjaszek-Matuszek, Smoleń, A., Ewa Obel, Lewicki, M.   +9 more
core   +1 more source

A Cross‐Species Hormone Knowledge Base With Multi‐Dimensional Data Integration and Intelligent Query Assistance

iMetaMed, EarlyView.
AHormoneDB is a no‐code platform that combines DOID‐standardized hormone–disease associations, regulatory prediction, and retrieval‐augmented generation‐based querying. In acromegaly, it nominated PTPN1 as a previously underappreciated candidate, demonstrating its capacity to accelerate mechanistic discovery.
Xingxing Huang, Yulong Bai, Jinfei Zhang, Lihong Zhang, Yongqiang Xing, Zhihui Zhang, Yuanping Lu   +6 more
wiley   +1 more source

Progress on diagnosis and treatment of pituitary adenoma in children

Chinese Journal of Contemporary Neurology and Neurosurgery
Pituitary adenoma is a benign intracranial tumor, commonly found in adults and occasionally in children. Pituitary adenoma is classified into secretory and non-secretory adenoma based on whether there is abnormal hormone secretion.
WANG Chuan-wei, DU Guo-ran, WANG Yan-zhao, ZHU Shao-lei, ZHANG Bin, GONG Jie   +5 more
doaj   +1 more source

Epigenetic dysregulation in pituitary tumors [PDF]

, 2019
Pituitary tumors are common intracranial neoplasms associated with significant morbidity due to hormonal dysregulation and neurologic symptoms. Somatic mutations are uncommon in sporadic pituitary adenomas, and only few monogenic conditions are ...

core   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Gene expression profile analysis of pituitary adenomas developed by HMGA transgenic mice [PDF]

, 2008
The High Mobility Group A (HMGA) nonhistone chromatin proteins alter chromatin structure and, thereby, regulate the transcription of several genes by either enhancing or suppressing transcription factors.
De Martino, Ivana
core   +1 more source

Frontiers in transition‐metal single‐atom electrocatalysts: Design tactics, mechanistic regulation, and electrochemical sensing technologies

InfoMat, EarlyView.
This review offers an overview of recent advances in the fundamental properties, synthesis methods, and structural optimization of transition‐metal single‐atom electrocatalysts for electrochemical sensing. It also provides a comprehensive summary of the emerging applications in electrochemical assays based on these materials, along with key challenges ...
Yue Cao, Bo‐Yu Chen, Yiru Sheng, Haoyuan Song, Linan Zhu, Xiaohan Yang, Yuehe Lin, Wenlei Zhu, Yang Zhou   +8 more
wiley   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source