Results 151 to 160 of about 57,640 (263)
Pediatric endocrine disorders: a review of intracranial findings and appropriate imaging. [PDF]
Pediatr RadiolShatadal A +3 more
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam +4 more
wiley +1 more source
Case Report: Rare collision tumors: ACTH-secreting pituitary neuroendocrine tumor and pituicytoma - histopathological and ultrastructural analysis. [PDF]
Front Endocrinol (Lausanne)Fernández SC +10 more
europepmc +1 more source
MEN1 Deficiency Drives Lung Cancer Progression via Activation of MMP10‐Mediated Angiogenesis
Cancer Science, EarlyView.MEN1 deficiency promotes JunD‐mediated upregulation of MMP10 expression, which cleaves pro‐HB‐EGF and activates endothelial EGFR. This triggers the PI3K/Akt and MEK/ERK signaling pathways, thereby driving angiogenesis and tumor progression. MMP10 inhibitor treatment blocks this cleavage, suppresses EGFR signaling, and thereby delays malignant ...
Chengyu Wei +17 more
wiley +1 more source
Case report of transsphenoidal meningocele presenting as airway obstruction and panhypopituitarism: Radiological findings and the role of CSF flow analysis. [PDF]
Radiol Case RepWong HTC, Chu YLE.
europepmc +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective The effect of transsphenoidal surgery (TSS) on the hypothalamic‐pituitary‐gonadal (HPG) axis in patients with non‐functioning pituitary adenomas (NFPA) is underexplored, especially in women. Our aim was to investigate the HPG axis function before and after TSS, its association with quality of life (QoL), and to identify factors that ...
Victor Hantelius +6 more
wiley +1 more source
Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management
Clinical Endocrinology, EarlyView.ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu +5 more
wiley +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective Evaluate the effects of osilodrostat short‐ and long‐term treatment on health‐related quality of life (HRQoL) in Cushing's disease. Design LINC 3 and LINC 4 studies (pooled analysis). Patients 185 patients (mean baseline total scores: Cushing's Quality of Life [CushingQoL], 44.0; Beck Depression Inventory II [BDI‐II], 15.6; EuroQol ...
John Newell‐Price +6 more
wiley +1 more source