Results 191 to 200 of about 532,520 (362)
P53 mutations in human adrenocortical neoplasms [PDF]
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B.+6 more
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ABSTRACT Objective This study examined the relative contributions of mediation and interaction by psychological distress to the association between job stressors and menstruation‐related symptoms. Design A cross‐sectional study. Setting Online survey in August 2023.
Natsu Sasaki+7 more
wiley +1 more source
Circadian Gene BMAL1 Regulation of Cellular Senescence in Thyroid Aging
BMAL1 downregulation during aging reduces NFKBIA expression, accelerating thyroid cellular senescence and impairing hormone synthesis. Circadian rhythm disruption exacerbates thyroid functional decline, highlighting the BMAL1‐NFKBIA axis as a key mediator of aging‐related thyroid dysfunction and offering insights for stabilizing thyroid health in aging
Dandan Zong+4 more
wiley +1 more source
Pituitary neuroendocrine tumors: a model for neuroendocrine tumor classification
S. Asa+28 more
semanticscholar +1 more source
A Novel GH Deficient Rat Model Reveals Cross‐Species Insights Into Aging
Mouse studies show disrupted GH signaling reduces body size, increases longevity, and improves health. We developed a CRISPR/Cas9 GH‐deficient rat model to address inconsistent rat evidence. GH‐deficient rats mirrored these findings, showing reduced body weight, increased body fat, enhanced insulin sensitivity, and altered gut microbiomes.
Soe Maung Maung Phone Myint+5 more
wiley +1 more source
An asynchronous double growth hormone-secreting pituitary neoplasm (PitNET) of a different proliferative potential [PDF]
Małgorzata Trofimiuk–Müldner+5 more
openalex +1 more source
Adults with prenatal alcohol exposure (PAE) are at increased risk for metabolic, immune, and cardiovascular disease. Little is known about the contribution of PAE to cerebrovascular disease, specifically during middle age, a time when stroke incidence and severity typically increase.
Shameena Bake+6 more
wiley +1 more source
Cardiac myxoma often simulates multisystem disease and initially defies diagnosis. In this paper, we present three cases of cardiac myxoma in adults.
Aquilina, Oscar+2 more
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