Results 191 to 200 of about 532,520 (362)

P53 mutations in human adrenocortical neoplasms [PDF]

open access: yes, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B.   +6 more
core  

Job Stress, Psychological Distress, and Menstruation‐Related Symptoms in Female Workers: A Cross‐Sectional Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective This study examined the relative contributions of mediation and interaction by psychological distress to the association between job stressors and menstruation‐related symptoms. Design A cross‐sectional study. Setting Online survey in August 2023.
Natsu Sasaki   +7 more
wiley   +1 more source

Circadian Gene BMAL1 Regulation of Cellular Senescence in Thyroid Aging

open access: yesAging Cell, EarlyView.
BMAL1 downregulation during aging reduces NFKBIA expression, accelerating thyroid cellular senescence and impairing hormone synthesis. Circadian rhythm disruption exacerbates thyroid functional decline, highlighting the BMAL1‐NFKBIA axis as a key mediator of aging‐related thyroid dysfunction and offering insights for stabilizing thyroid health in aging
Dandan Zong   +4 more
wiley   +1 more source

Pituitary neuroendocrine tumors: a model for neuroendocrine tumor classification

open access: yesModern Pathology, 2021
S. Asa   +28 more
semanticscholar   +1 more source

A Novel GH Deficient Rat Model Reveals Cross‐Species Insights Into Aging

open access: yesAging Cell, EarlyView.
Mouse studies show disrupted GH signaling reduces body size, increases longevity, and improves health. We developed a CRISPR/Cas9 GH‐deficient rat model to address inconsistent rat evidence. GH‐deficient rats mirrored these findings, showing reduced body weight, increased body fat, enhanced insulin sensitivity, and altered gut microbiomes.
Soe Maung Maung Phone Myint   +5 more
wiley   +1 more source

An asynchronous double growth hormone-secreting pituitary neoplasm (PitNET) of a different proliferative potential [PDF]

open access: gold
Małgorzata Trofimiuk–Müldner   +5 more
openalex   +1 more source

Prenatal alcohol exposure worsens acute but not long‐term cognitive outcomes due to stroke in middle‐aged Sprague–Dawley rat offspring

open access: yesAlcohol, Clinical and Experimental Research, Volume 49, Issue 7, Page 1459-1472, July 2025.
Adults with prenatal alcohol exposure (PAE) are at increased risk for metabolic, immune, and cardiovascular disease. Little is known about the contribution of PAE to cerebrovascular disease, specifically during middle age, a time when stroke incidence and severity typically increase.
Shameena Bake   +6 more
wiley   +1 more source

The great simulator [PDF]

open access: yes, 1993
Cardiac myxoma often simulates multisystem disease and initially defies diagnosis. In this paper, we present three cases of cardiac myxoma in adults.
Aquilina, Oscar   +2 more
core  

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