Results 61 to 70 of about 500,171 (198)
Alʹmanah Kliničeskoj Mediciny, 2018 Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer's syndrome) is a group of heterogeneous inherited diseases, with its pathogenesis related to hyperplasia or neoplasms of several endocrine glands.
L. Ya. Rozhinskaya +7 more
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Epidemiology of Functioning Pituitary Adenomas [PDF]
Endocrinology and Metabolism, 2020 Pituitary adenomas (PAs) are defined as benign monoclonal tumors in the pituitary gland that cause symptoms due to either hormonal hypersecretion or a space-occupying effect, and are classified as functioning or non-functioning.
Sang Ouk Chin
doaj +1 more source
International Journal of Endocrinology, 2015 Pituitary adenomas, monoclonal in origin, are the most common intracranial neoplasms. Altered gene expression as well as somatic mutations is detected frequently in pituitary adenomas.
Peng Zhao +7 more
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Targeted treatment with somatostatin analogues: widening horizons of clinical practice
Alʹmanah Kliničeskoj Mediciny, 2022 Targeted treatment with somatostatin analogues (SA) in acromegaly and neuroendocrine neoplasms may have some benefits compared to curative treatments, because these agents decrease excessive hormone secretion and exert a tumor-suppressive effect ...
Vyacheslav S. Pronin +3 more
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No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]
, 1933 G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P. +3 more
core
Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]
, 2019 Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés +6 more
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DiagnosticsBackground: Pituitary adenomas represent the most common pituitary disorder, with an estimated prevalence as high as 20%, and they can manifest with hormone hypersecretion or deficiency, neurological symptoms from mass effect, or incidental findings on ...
Janez Ravnik +8 more
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Ukrainian Neurosurgical Journal, 2015 Introduction. Pituitary tumors take the third place in a structure of CNS neoplasms and ranged from 4 to 17% of all brain tumors.The purpose.
Andrey Gryazov +6 more
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Diagnosis and management of pituitary apoplexy: a Tunisian data
Chinese Neurosurgical Journal, 2023 Background Pituitary apoplexy (PA) is defined as the hemorrhage or the infraction of a pituitary adenoma. Aiming to determine the epidemiological, clinical, paraclinical characteristics as well as management and outcomes of PA in our population, we ...
Faten Hadj Kacem +9 more
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Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm [PDF]
arXiv, 2023 We develop a modeling framework for cancer progression that distinguishes the order of two possible mutations. Recent observations and information on myeloproliferative neoplasms are analyzed within our framework. In some patients with myeloproliferative neoplasms, two genetic mutations can be found, JAK2 V617F and TET2.
arxiv