Results 41 to 50 of about 68,420 (313)

Radiation-associated sarcoma of the skull base after irradiation for pituitary adenoma

open access: yesRare Tumors, 2012
Secondary, radiation-induced neoplasms represent a significant long-term risk after radiation treatment, and radiation-induced sarcomas (RAS) have an especially poor prognosis. These have rarely been reported after irradiation for pituitary adenomas.
Cara L. Sedney   +4 more
doaj   +1 more source

Comprehensive Genomic Characterization of A Case of Granular Cell Tumor of the Posterior Pituitary Gland: A Case Report

open access: yesFrontiers in Endocrinology, 2021
Granular cell tumors of the pituitary belong to a rare family of neoplasms, arising from the posterior pituitary gland. Although considered benign, they may cause significant morbidity and residual disease after resection can lead to poor clinical ...
Christopher S. Hong   +7 more
doaj   +1 more source

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]

open access: yes, 2016
PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R.   +13 more
core   +3 more sources

Treatment of pituitary neoplasms with temozolomide [PDF]

open access: yesCancer, 2010
AbstractTemozolomide, an orally administered alkylating agent, is used to treat malignant gliomas. Recent reports also have documented its efficacy in the treatment of pituitary adenomas and carcinomas. Temozolomide methylates DNA and thereby exhibits an antitumor effect.
Luis V, Syro   +9 more
openaire   +2 more sources

The evolution in pituitary tumour classification: a clinical perspective

open access: yesEndocrine Oncology, 2023
Objective: Pituitary tumours comprise a pathologically and clinically diverse group of neoplasms. Classification frameworks have changed dramatically in the past two decades, reflecting improving understanding of tumour biology.
Nele F Lenders   +3 more
doaj   +1 more source

A case report of a rare intramuscular granular cell tumor [PDF]

open access: yes, 2015
Background: Granular cell tumors (GCTs) were firstly described by Weber in 1854 and 70 years later by Abrikossoff and classified as benign tumors. Originally considered muscle tumors, they have been identified as neural lesions, due to their close ...
Cacciotti, Jessica   +8 more
core   +1 more source

Identification of Differentially Expressed Genes in Pituitary Adenomas by Integrating Analysis of Microarray Data

open access: yesInternational Journal of Endocrinology, 2015
Pituitary adenomas, monoclonal in origin, are the most common intracranial neoplasms. Altered gene expression as well as somatic mutations is detected frequently in pituitary adenomas.
Peng Zhao   +7 more
doaj   +1 more source

Relapse of the pituitary adenoma with a change of its hormonal activity in a female patient with multiple endocrine neoplasia syndrome type 1

open access: yesAlʹmanah Kliničeskoj Mediciny, 2018
Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer's syndrome) is a group of heterogeneous inherited diseases, with its pathogenesis related to hyperplasia or neoplasms of several endocrine glands.
L. Ya. Rozhinskaya   +7 more
doaj   +1 more source

Targeted treatment with somatostatin analogues: widening horizons of clinical practice

open access: yesAlʹmanah Kliničeskoj Mediciny, 2022
Targeted treatment with somatostatin analogues (SA) in acromegaly and neuroendocrine neoplasms may have some benefits compared to curative treatments, because these agents decrease excessive hormone secretion and exert a tumor-suppressive effect ...
Vyacheslav S. Pronin   +3 more
doaj   +1 more source

The Impact of Surgical Telementoring on Reducing the Complication Rate in Endoscopic Endonasal Surgery of the Skull Base

open access: yesDiagnostics
Background: Pituitary adenomas represent the most common pituitary disorder, with an estimated prevalence as high as 20%, and they can manifest with hormone hypersecretion or deficiency, neurological symptoms from mass effect, or incidental findings on ...
Janez Ravnik   +8 more
doaj   +1 more source

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