Dysregulation of Cortisol Metabolism in Equine Pituitary Pars Intermedia Dysfunction. [PDF]
Endocrinology, 2018 Equine Cushing's Disease (Pituitary pars intermedia dysfunction (PPID)) is a common condition of older horses but its pathophysiology is complex and poorly understood.
Morgan RA +8 more
europepmc +7 more sources
Long‐Term Response of Equids With Pituitary Pars Intermedia Dysfunction to Treatment With Pergolide [PDF]
Journal of Veterinary Internal MedicineBackground Limited data document long‐term responses of equids with pituitary pars intermedia dysfunction (PPID) to pergolide treatment. Objectives Report clinical response, medical problems, outcome, and owner satisfaction with pergolide treatment of ...
Harold C. Schott II +3 more
doaj +4 more sources
Lamellar pathology in horses with pituitary pars intermedia dysfunction
Equine Veterinary Journal, 2016 Reasons for performing study: Hoof lamellar pathology in horses with pituitary pars intermedia dysfunction (PPID) has not been described previously. Objectives: To describe the histomorphometry and pathological lesions in hoof lamellar tissue of
Dianne Mcfarlane, C M Mcgowan
exaly +4 more sources
Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma [PDF]
Pesquisa Veterinária Brasileira, 2023 : The clinical syndrome of the pituitary pars intermedia dysfunction (PPID) is the most common endocrinopathy of older horses. This syndrome is characterized by several clinical and pathological changes, which are usually associated with adenomas of the ...
Anderson H. Gris +7 more
doaj +3 more sources
Diagnosis of equine pituitary pars intermedia dysfunction
The Veterinary Journal, 2023 Equine pituitary pars intermedia dysfunction (PPID) is common in aged horses. The majority of horses respond well to treatment, but treatment is lifelong, meaning accurate diagnosis of PPID is important.
Joanne L. Ireland +7 more
core +5 more sources
Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction [PDF]
BMC Veterinary Research, 2020 Background Pituitary pars intermedia dysfunction (PPID) develops slowly in aged horses as degeneration of hypothalamic dopaminergic neurons leads to proliferation of pars intermedia (PI) melanotropes through hyperplasia and adenoma formation.
Jessica S. Fortin +6 more
doaj +2 more sources
Repeatability of a thyrotropin‐releasing hormone stimulation test for diagnosis of pituitary pars intermedia dysfunction in mature horses [PDF]
Journal of Veterinary Internal Medicine, 2021 Background Pituitary pars intermedia dysfunction (PPID) is a common endocrinopathy of horses diagnosed with a thyrotropin‐releasing hormone (TRH) stimulation test.
Yan Ning Kam +3 more
doaj +2 more sources
Equine pituitary pars intermedia dysfunction: Identifying research priorities for diagnosis, treatment and prognosis through a priority setting partnership. [PDF]
PLoS ONE, 2021 Pituitary pars intermedia dysfunction (PPID) is the most prevalent endocrine disorder of older equids. To date, key research areas likely to have the greatest impact on equine health have not been identified.
Rebecca C Tatum +3 more
doaj +2 more sources
Impact of pituitary pars intermedia dysfunction on inflammation within the equine reproductive tract of the mare [PDF]
Frontiers in Veterinary ScienceIntroductionPituitary pars intermedia dysfunction (PPID) is an age-related endocrinopathy associated with elevated systemic inflammation, and specifically an upregulation of interleukin-8 (IL-8).
Jocelyn Howard +9 more
doaj +2 more sources
Profiles of pro-opiomelanocortin and encoded peptides, and their processing enzymes in equine pituitary pars intermedia dysfunction. [PDF]
PLoS ONE, 2018 Equine pituitary pars intermedia dysfunction (PPID) is characterized by hyperplasia of the pars intermedia (PI) melanotrophs of the pituitary gland (PG), and increased production of proopiomelanocortin (POMC).
James L Carmalt +4 more
doaj +2 more sources