Results 21 to 30 of about 3,292,689 (405)
Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]
, 2016 PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R. +13 more
core +3 more sources
BMC Medical Informatics and Decision Making, 2023 Background Detecting brain tumors in their early stages is crucial. Brain tumors are classified by biopsy, which can only be performed through definitive brain surgery.
Soheila Saeedi +3 more
semanticscholar +1 more source
The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]
, 2010 Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y. +2 more
core +1 more source
Frontiers in Oncology, 2021 BackgroundThe new World Health Organization (WHO) classification system proposed a cell lineage-based classification scheme for pituitary adenomas in which transcription factors (TFs) play a major role as key classifiers.
Seung Woo Hong +14 more
doaj +1 more source
Brain Tumor Detection Based on Deep Learning Approaches and Magnetic Resonance Imaging
Cancers, 2023 Simple Summary In this research, we addressed the challenging task of brain tumor detection in MRI scans using a large collection of brain tumor images.
A. Abdusalomov +2 more
semanticscholar +1 more source
Endocrinology and Metabolism Clinics of North America, 2015 Pituitary tumors are commonly encountered intracranial neoplasms that are invariably benign. Classic oncogene mutations are not encountered in these tumors, and disrupted cell cycle control and growth factor signaling likely contribute to pathogenesis and natural history.
openaire +2 more sources
Pituitary, 2017 IntroductionWith the goal of generate uniform criteria among centers dealing with pituitary tumors and to enhance patient care, the Pituitary Society decided to generate criteria for developing Pituitary Tumors Centers of Excellence (PTCOE).MethodsTo ...
F. Casanueva +98 more
semanticscholar +1 more source
Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]
, 2001 Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta +7 more
core +1 more source
Pituitary, 2023 The Pituitary Society established the concept and mostly qualitative parameters for defining uniform criteria for Pituitary Tumor Centers of Excellence (PTCOEs) based on expert consensus.
A. Giustina +18 more
semanticscholar +1 more source
Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing’s Disease
Frontiers in Endocrinology, 2021 PurposeTo investigate the role of heat-shock protein Hsp90 in adrenocorticotropic hormone (ACTH)-secreting cells, and to explore the potential clinical application of an inhibitor of Hsp90, 17-N-allylamino-17-demethoxygeldanamycin(17-AAG) in ...
Yue Shen +17 more
doaj +1 more source