Results 21 to 30 of about 3,152,858 (268)

Multiparametric MRI Features Predict the SYP Gene Expression in Low-Grade Glioma Patients: A Machine Learning-Based Radiomics Analysis

Frontiers in Oncology, 2021
PurposeSynaptophysin (SYP) gene expression levels correlate with the survival rate of glioma patients. This study aimed to explore the feasibility of applying a multiparametric magnetic resonance imaging (MRI) radiomics model composed of a convolutional ...
Zheng Xiao, Shun Yao, Shun Yao, Zong-ming Wang, Di-min Zhu, Ya-nan Bie, Shi-zhong Zhang, Wen-li Chen   +7 more
doaj   +1 more source

Case Report: Temozolomide Treatment of Refractory Prolactinoma Resistant to Dopamine Agonists

Frontiers in Endocrinology, 2021
Therapeutic agents for refractory prolactinomas that are resistant to dopamine agonists (DAs) are troublesome, and surgery often only removes a large part of the tumor without complete remission.
Hao Tang, Yijun Cheng, Jinyan Huang, Jianfeng Li, Benyan Zhang, Zhe Bao Wu   +5 more
doaj   +1 more source

MRI-based brain tumor detection using convolutional deep learning methods and chosen machine learning techniques

BMC Medical Informatics and Decision Making, 2023
Background Detecting brain tumors in their early stages is crucial. Brain tumors are classified by biopsy, which can only be performed through definitive brain surgery.
Soheila Saeedi, S. Rezayi, Hamidreza Keshavarz, Sharareh R. Niakan Kalhori   +3 more
semanticscholar   +1 more source

Brain Tumor Detection Based on Deep Learning Approaches and Magnetic Resonance Imaging

Cancers, 2023
Simple Summary In this research, we addressed the challenging task of brain tumor detection in MRI scans using a large collection of brain tumor images.
A. Abdusalomov, Mukhriddin Mukhiddinov, T. Whangbo   +2 more
semanticscholar   +1 more source

Case Report: End-Stage Recurrent Glioblastoma Treated With a New Noninvasive Non-Contact Oncomagnetic Device

Frontiers in Oncology, 2021
Alternating electric field therapy has been approved for glioblastoma (GBM). We have preclinical evidence for anticancer effects in GBM cell cultures and mouse xenografts with an oscillating magnetic field (OMF) generating device.
David S. Baskin, David S. Baskin, David S. Baskin, Martyn A. Sharpe, Martyn A. Sharpe, Lisa Nguyen, Lisa Nguyen, Santosh A. Helekar, Santosh A. Helekar, Santosh A. Helekar   +9 more
doaj   +1 more source

Clinical Relevance of New World Health Organization Classification System for Pituitary Adenomas: A Validation Study With 2-Year Experience

Frontiers in Oncology, 2021
BackgroundThe new World Health Organization (WHO) classification system proposed a cell lineage-based classification scheme for pituitary adenomas in which transcription factors (TFs) play a major role as key classifiers.
Seung Woo Hong, Se Hoon Kim, Se Hoon Kim, Seung Hoon Lim, Eun Jig Lee, Eun Jig Lee, Eun Jig Lee, Sun Ho Kim, Sun Ho Kim, Cheol Ryong Ku, Cheol Ryong Ku, Cheol Ryong Ku, Eui Hyun Kim, Eui Hyun Kim, Eui Hyun Kim   +14 more
doaj   +1 more source

Work disability and its determinants in patients with pituitary tumor-related disease

Pituitary, 2018
IntroductionPituitary tumors may have a considerable impact on patients’ functional status, including paid employment, yet research in this area is sparse.ObjectiveTo describe work disability and its determinants in patients treated for a pituitary tumor.
Daniel J. Lobatto, Anath N V Steffens, A. Z. Zamanipoor Najafabadi, C. Andela, A. Pereira, W. B. van den Hout, W. Peul, T. V. Vliet Vlieland, N. Biermasz, W. V. van Furth   +9 more
semanticscholar   +1 more source

Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing’s Disease

Frontiers in Endocrinology, 2021
PurposeTo investigate the role of heat-shock protein Hsp90 in adrenocorticotropic hormone (ACTH)-secreting cells, and to explore the potential clinical application of an inhibitor of Hsp90, 17-N-allylamino-17-demethoxygeldanamycin(17-AAG) in ...
Yue Shen, Yue Shen, Chenxing Ji, Chenxing Ji, Xuemin Jian, Juan Zhou, Qilin Zhang, Qilin Zhang, Nidan Qiao, Nidan Qiao, Yichao Zhang, Yichao Zhang, Xuefei Shou, Xuefei Shou, Xiang Zhou, Xiang Zhou, Zengyi Ma, Zengyi Ma   +17 more
doaj   +1 more source

Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement

Pituitary, 2017
IntroductionWith the goal of generate uniform criteria among centers dealing with pituitary tumors and to enhance patient care, the Pituitary Society decided to generate criteria for developing Pituitary Tumors Centers of Excellence (PTCOE).MethodsTo ...
F. Casanueva, A. Barkan, Michael Buchfelder, A. Klibanski, Edward R. Laws, J. Loeffler, S. Melmed, Pietro Mortini, J. Wass, Andrea Giustina, Alin Abreu Julio Cristina Ariel L Albert Anat Ignacio M Lomba Abucham Alvarez-Escola Barkan Beckers Ben-Sh, A. Lomba, J. Abucham, C. Alvarez-Escola, A. Barkan, Albert Beckers, Anat Ben-Shlomo, I. Bernabéu, M. Bidlingmaier, N. Biermasz, B. Biller, C. Boguszewski, M. Bolanowski, J. Bollerslev, V. Bonert, M. Bronstein, O. Bruno, Michael Buchfelder, J. Carmichael, P. Caron, P. Chanson, F. Casanueva, Richard N. Clayton, A. Colao, F. Cordido, L. De Marinis, R. Fahlbusch, M. Fleseriu, A. Formenti, P. Freda, H. Fukuoka, E. Ghigo, Andrea Giustina, Y. Greenman, E. Grineva, Ashley Grossman, M. Gurnell, A. Heaney, A. Hoffman, I. Ilovayskaya, G. Johannsson, P. Kadıoğlu, N. Karavitaki, L. Katznelson, F. Keleştimur, D. Kelly, A. Klibanski, Ken K. Y. Ho, M. Kršek, A. Lacroix, Edward R. Laws, Jay StevenLoeffler, M. Losa, Jens Otto Lunde Jørgensen, A. Luger, S. Mallea-Gil, A. Mamelak, G. Mazziotti, A. McCormack, S. Melmed, M. Mercado, Pietro Mortini, S. Neggers, G. Ning, N. Oyesiku, V. Popović, M. Petakov, S. Petersenn, Michael Pfeifer, A. Picó, M. Domingo, G. Raverot, M. Reincke, M. Gadelha, R. Salvatori, S. Samson, A. Shimatsu, Ilan Shimon, Paul Stewart, C. Strasburger, B. Swearingen, P. Trainer, N. Tritos, S. Tsagarakis, A. J. van der Lely, L. Vilar, R. Villar-Taibo, J. Wass, M. Zatelli   +98 more
semanticscholar   +1 more source

Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells

Frontiers in Oncology, 2021
Electromagnetic fields (EMF) raise intracellular levels of reactive oxygen species (ROS) that can be toxic to cancer cells. Because weak magnetic fields influence spin state pairing in redox-active radical electron pairs, we hypothesize that they disrupt
Martyn A. Sharpe, Martyn A. Sharpe, Martyn A. Sharpe, David S. Baskin, David S. Baskin, David S. Baskin, David S. Baskin, Kumar Pichumani, Kumar Pichumani, Kumar Pichumani, Kumar Pichumani, Omkar B. Ijare, Omkar B. Ijare, Omkar B. Ijare, Santosh A. Helekar, Santosh A. Helekar, Santosh A. Helekar, Santosh A. Helekar   +17 more
doaj   +1 more source