Results 21 to 30 of about 3,259,919 (360)

The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]

, 2010
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y., Stapleton, Christopher J., Weiss, Martin H.   +2 more
core   +1 more source

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta, Hopfner, Ursula, Lohrer, Penny, Losa, Marco, Pagotto, Uberto, Renner, Ulrich, Stalla, Günter K., Uhl, Eberhard   +7 more
core   +1 more source

Pilot study to define criteria for Pituitary Tumors Centers of Excellence (PTCOE): results of an audit of leading international centers

Pituitary, 2023
The Pituitary Society established the concept and mostly qualitative parameters for defining uniform criteria for Pituitary Tumor Centers of Excellence (PTCOEs) based on expert consensus.
A. Giustina, M. M. Uygur, S. Frara, A. Barkan, N. Biermasz, P. Chanson, P. Freda, M. Gadelha, U. Kaiser, S. Lamberts, E. Laws, L. Nachtigall, V. Popović, M. Reincke, C. Strasburger, A. J. van der Lely, J. Wass, S. Melmed, F. Casanueva   +18 more
semanticscholar   +1 more source

Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing’s Disease

Frontiers in Endocrinology, 2021
PurposeTo investigate the role of heat-shock protein Hsp90 in adrenocorticotropic hormone (ACTH)-secreting cells, and to explore the potential clinical application of an inhibitor of Hsp90, 17-N-allylamino-17-demethoxygeldanamycin(17-AAG) in ...
Yue Shen, Yue Shen, Chenxing Ji, Chenxing Ji, Xuemin Jian, Juan Zhou, Qilin Zhang, Qilin Zhang, Nidan Qiao, Nidan Qiao, Yichao Zhang, Yichao Zhang, Xuefei Shou, Xuefei Shou, Xiang Zhou, Xiang Zhou, Zengyi Ma, Zengyi Ma   +17 more
doaj   +1 more source

Work disability and its determinants in patients with pituitary tumor-related disease

Pituitary, 2018
IntroductionPituitary tumors may have a considerable impact on patients’ functional status, including paid employment, yet research in this area is sparse.ObjectiveTo describe work disability and its determinants in patients treated for a pituitary tumor.
Daniel J. Lobatto, Anath N V Steffens, A. Z. Zamanipoor Najafabadi, C. Andela, A. Pereira, W. B. van den Hout, W. Peul, T. V. Vliet Vlieland, N. Biermasz, W. V. van Furth   +9 more
semanticscholar   +1 more source

Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells

Frontiers in Oncology, 2021
Electromagnetic fields (EMF) raise intracellular levels of reactive oxygen species (ROS) that can be toxic to cancer cells. Because weak magnetic fields influence spin state pairing in redox-active radical electron pairs, we hypothesize that they disrupt
Martyn A. Sharpe, Martyn A. Sharpe, Martyn A. Sharpe, David S. Baskin, David S. Baskin, David S. Baskin, David S. Baskin, Kumar Pichumani, Kumar Pichumani, Kumar Pichumani, Kumar Pichumani, Omkar B. Ijare, Omkar B. Ijare, Omkar B. Ijare, Santosh A. Helekar, Santosh A. Helekar, Santosh A. Helekar, Santosh A. Helekar   +17 more
doaj   +1 more source

Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement

Pituitary, 2017
IntroductionWith the goal of generate uniform criteria among centers dealing with pituitary tumors and to enhance patient care, the Pituitary Society decided to generate criteria for developing Pituitary Tumors Centers of Excellence (PTCOE).MethodsTo ...
F. Casanueva, A. Barkan, Michael Buchfelder, A. Klibanski, E. Laws, J. Loeffler, S. Melmed, Pietro Mortini, J. Wass, A. Giustina, Alin Abreu Julio Cristina Ariel L Albert Anat Ignacio M Lomba Abucham Alvarez-Escola Barkan Beckers Ben-Sh, A. Lomba, J. Abucham, C. Alvarez-Escola, A. Barkan, Albert Beckers, Anat Ben-Shlomo, I. Bernabéu, M. Bidlingmaier, N. Biermasz, B. Biller, C. Boguszewski, M. Bolanowski, J. Bollerslev, V. Bonert, M. Bronstein, O. Bruno, Michael Buchfelder, J. Carmichael, P. Caron, P. Chanson, F. Casanueva, Richard N. Clayton, A. Colao, F. Cordido, L. De Marinis, R. Fahlbusch, M. Fleseriu, A. Formenti, P. Freda, H. Fukuoka, E. Ghigo, A. Giustina, Y. Greenman, E. Grineva, Ashley Grossman, M. Gurnell, A. Heaney, A. Hoffman, I. Ilovayskaya, G. Johannsson, P. Kadıoğlu, N. Karavitaki, L. Katznelson, F. Keleştimur, D. Kelly, A. Klibanski, Ken K. Y. Ho, M. Kršek, A. Lacroix, E. Laws, Jay StevenLoeffler, M. Losa, Jens Otto Lunde Jørgensen, A. Luger, Susana M. Mallea-Gil, A. Mamelak, G. Mazziotti, A. McCormack, S. Melmed, M. Mercado, Pietro Mortini, S. Neggers, G. Ning, N. Oyesiku, V. Popović, M. Petakov, S. Petersenn, Michael Pfeifer, A. Picó, M. Domingo, G. Raverot, M. Reincke, M. Gadelha, R. Salvatori, S. Samson, A. Shimatsu, Ilan Shimon, Paul Stewart, C. Strasburger, B. Swearingen, P. Trainer, N. Tritos, S. Tsagarakis, A. J. van der Lely, L. Vilar, R. Villar-Taibo, J. Wass, M. Zatelli   +98 more
semanticscholar   +1 more source

Evolution of Minimally Invasive Approaches to the Sella and Parasellar Region

International Archives of Otorhinolaryngology, 2014
Introduction Given advancements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques, and anatomical understanding, the endonasal endoscopic approach has rapidly evolved into a widely utilized technique for ...
Robert G. Louis, Amy Eisenberg, Garni Barkhoudarian, Chester Griffiths, Daniel F. Kelly   +4 more
doaj   +1 more source

How to Classify and Define Pituitary Tumors: Recent Advances and Current Controversies

Frontiers in Endocrinology, 2021
Pituitary tumors are very complex and heterogeneous and have a very wide range of proliferative and aggressive behaviors, and how to define and classify these tumors remains controversial.
Congxin Dai, Jun Kang, Xiaohai Liu, Yong Yao, Yong Yao, Haijun Wang, Haijun Wang, Renzhi Wang, Renzhi Wang   +8 more
doaj   +1 more source

Successful Treatment of Intracranial Glioblastoma Xenografts With a Monoamine Oxidase B-Activated Pro-Drug

EBioMedicine, 2015
The last major advance in the treatment of glioblastoma multiforme (GBM) was the introduction of temozolomide in 1999. Treatment with temozolomide following surgical debulking extends survival rate compared to radiotherapy and debulking alone.
Martyn A. Sharpe, Andrew D. Livingston, Taylor L. Gist, Pardip Ghosh, Junyan Han, David S. Baskin   +5 more
doaj   +1 more source