Results 91 to 100 of about 93,749 (369)

Circulating FK506 binding protein 51 mRNA expression in patients with pituitary adenomas

Heliyon, 2023
Background: FK506 binding protein 51 (FKBP5) is a co-chaperone regulator of the glucocorticoid receptor (GR). Recent studies have reported increased FKBP5 mRNA in the circulation from patients with Cushing disease (CD) which returned to comparable levels
Yingying Yang, Lilit Babayan, Argishty Mirzakhanian, Nvard Sisliyan, Dongyun Zhang, Carolina Hurtado, Abdul Zahid, Marvin Bergsneider, Won Kim, Marilene B. Wang, Anthony P. Heaney   +10 more
doaj  

Clinical study of endoscopic treatment of a sellar pituitary adenomas with sellar diaphragm defect

BMC Neurology, 2020
Background Invasive growth of pituitary macroadenomas to the suprasellar region occurs commonly. Pituitary adenomas show varying growth patterns when the sellar diaphragm is absent, and they are often confused with other common tumors in the sellar ...
Zhuoru Jin, Xinyu Wu, Yibao Wang
doaj   +1 more source

Robust Brain MRI Image Classification with SIBOW-SVM [PDF]

arXiv, 2023
The majority of primary Central Nervous System (CNS) tumors in the brain are among the most aggressive diseases affecting humans. Early detection of brain tumor types, whether benign or malignant, glial or non-glial, is critical for cancer prevention and treatment, ultimately improving human life expectancy.
arxiv  

Cohesins: Crossroad Between Cornelia de Lange Spectrum and Cancer Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The cohesin complex plays crucial roles in DNA repair, chromatid separation, and gene transcription regulation. Pathogenic variants in cohesins or dysfunctional transcriptional regulators lead to cohesinopathies, a broader group of disorders including Cornelia de Lange Spectrum (CdLSp), for which the prevalence of cancer cases remains unclear.
Laura Rigotti, Stefano Rebellato, Antonella Lettieri, Silvia Castiglioni, Milena Mariani, Simona Totaro, Claudia Saitta, Cristina Gervasini, Grazia Fazio, Valentina Massa, Giovanni Cazzaniga, Angelo Selicorni   +11 more
wiley   +1 more source

Metabolic profiling reveals distinct metabolic alterations in different subtypes of pituitary adenomas and confers therapeutic targets

Journal of Translational Medicine, 2019
Background Pituitary adenomas are common brain tumors. Although transsphenoidal surgery are able to achieve extensive tumor removal, the rate of recurrence ranges from 5 to 20% depending on the different subtype.
Jie Feng, Hua Gao, Qi Zhang, Yang Zhou, Chuzhong Li, Sida Zhao, Lichuan Hong, Jinjin Yang, Shuyu Hao, Wan Hong, Zhengping Zhuang, Guowang Xu, Yazhuo Zhang   +12 more
doaj   +1 more source

The effect of endoscopic transsphenoidal somatotroph tumors resection on pituitary hormones: systematic review and meta-analysis

World Journal of Surgical Oncology, 2023
Purpose Currently, endoscopic transsphenoidal surgery is the main treatment for pituitary neuroendocrine tumors (PitNETs). Excision of the tumor may have positive or negative effects on pituitary endocrine function, and the pituitary function of ...
Ding Nie, Qiuyue Fang, Wakam Wong, Songbai Gui, Peng Zhao, Chuzhong Li, Yazhuo Zhang   +6 more
doaj   +1 more source

A New Deep Hybrid Boosted and Ensemble Learning-based Brain Tumor Analysis using MRI [PDF]

arXiv, 2022
Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In this regard, a novel two-phase deep learning-based framework is proposed to detect and categorize brain tumors in ...
arxiv  

Pituitary tumors in the elderly [PDF]

European Journal of Endocrinology, 1999
The proportion of elderly subjects is growing in Western countries and, as a consequence, several diseases are now recognized with increasing frequency in the older segment of the population. Pituitary tumors are no exception to the rule. However, the presentation, diagnosis and management of pituitary tumors in the elderly, defined as patients older ...
openaire   +3 more sources

A Novel International Endoscopic Sphenoid Surgery Classification (IESSC): A Delphi Consensus

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Advancements in endoscopic sinus and skull base surgery created a need for standardized terminology to describe sphenoid sinus surgery. Although classification systems exist for other sinuses, one for endoscopic sphenoid sinus surgery is lacking.
Hussain Albaharna, Abdulaziz Alrasheed, Abdulaziz AlQahtani, Alkis J. Psaltis, Amin Javer, Cem Meco, Christos Georgalas, Eric W. Wang, Isam Alobid, Kazuhiro Omura, Luis Fernando Macias‐Valle, Marc Tewfik, Narayanan Prepageran, Paolo Battaglia, Paolo Castelnuovo, Ricardo Carrau, Richard Douglas, Richard Harvey, Roy R. Casiano, Shahzada Ahmed, Saad Alsaleh   +20 more
wiley   +1 more source

Resistance to dopamine agonists and somatostatin analogues in pituitary tumors: focus on cytoskeleton involvement

Frontiers in Endocrinology, 2015
Pituitary tumors, that origin from excessive proliferation of a specific subtype of pituitary cell, are mostly benign tumors, but may cause significant morbidity in affected patients, including visual and neurologic manifestations from mass-effect, or ...
Erika ePeverelli, Donatella eTreppiedi, Elena eGiardino, Eleonora eVitali, Andrea G Lania, Giovanna eMantovani   +5 more
doaj   +1 more source