Results 81 to 90 of about 5,801,283 (182)
PIVKA-II plasma levels as markers of subclinical vitamin K deficiency in term infants
Background: As the vitamin K content of human milk is low and the newborn infant's stores of vitamin K are small, vitamin K deficiency with hemorrhage in the newborn is a worldwide problem.
Dituri, F. +15 more
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Protein induced by vitamin K absence (PIVKA-II) has been used for the evaluation of vitamin K deficiency in the newborn. Differing PIVKA-II detection rates in various studies on hemorrhagic disease of the newborn have not been explained ...
N Uluşahin, S Arsan, F Ertogan
doaj
Immunohistochemical study for PIVKA-II in hepatocellular carcinoma.
吸引肝生検で診断された肝細胞癌(HCC)患者70例(A群:腫瘍径2cm以下23例,B群:径2~5cm 13例,C群:径5cm以上および多結節34例)の肝癌組織を抗PIVKA-II抗体を用いた酵素抗体間接法で染色し光顕・電顕的に観察した.HCC 70例のうち組織PIVKA-II染色陽性は29例(41.4%)であった.細胞異型度別の陽性率には有意差を認めなかったが,中等度異型度群(Ed-II)で強く染色される傾向があった.腫瘍径別の陽性率はA群39.1%, B群38.5%, C群44.1%であり,A群での血中PIVKA-II陽性例は1例のみであった.また,腫瘍切除後に血中PIVKA-IIの正常化した症例が認められたことや電顕的に肝癌細胞の粗面小胞体にPIVKA-IIに対する反応産物が認められたことから ...
openaire +2 more sources
Background: The staging of Hepatocellular carcinoma (HCC) requires evaluating the tumor size and number, liver function, physical performance, tumor invasion, extrahepatic metastasis, and clinical symptoms. Biomarkers such as neutrophil-lymphocyte ratio (
Febry Rahmayani +2 more
doaj +1 more source
目的探讨血清异常凝血酶原(PIVKA-II)在胰腺癌诊断中的应用价值。方法收集2018年1月至2019年6月于北京清华长庚医院初次诊断为胰腺癌的住院患者57例,胰腺炎患者50例,健康体检者50例,分别用化学发光法检测PIVKA-II、CA199、CEA、AFP,比较4个指标在胰腺癌组、胰腺炎组和健康对照组的差异,并作ROC曲线,比较PIVKA-II、CA199、CEA鉴别诊断胰腺良恶性疾病的效能;根据肿瘤位置,将胰腺癌组分为胰头癌组和胰体胰尾癌组,比较两组PIVKA-II、CA199、CEA水平的差异 ...
董静肖 +3 more
doaj
Studies on Factors Affecting Plasma PIVKA-II Levels in Hepatocellular Carcinoma [PDF]
In order to diagnose hepatocellular carcinoma (HCC), plasma levels of protein induced by vitamin K absence or antagonist-II (PIVKA-II) were determined by an enzyme-linked immunosorbent assay (ELISA). Positive reaction was noted in 34 (68%) of 50 patients
Shibasaki, Koichi +13 more
core +1 more source
Background: Hepatocellular carcinoma (HCC) is usually asymptomatic in the early stage and does not show elevated alpha-feto protein (AFP). AFP shows 60–80% sensitivity in diagnosing HCC.
Iman A. Abd El Gawad +4 more
doaj +1 more source
BACKGROUND & AIMS: In this study, we investigated the clinical usefulness of AFP and PIVKA-II in subdividing prognostic groups in patients with locally advanced HCC treated locally. METHODS: Patients who had undergone local treatment for locally advanced
안상훈 +5 more
core +1 more source
Hepatozelluläres Karzinom: PIVKA-II: zuverlässiger Marker für extrahepatische Läsionen
Die Risikoabschätzung der Entwicklung extrahepatischer Metastasen ist ein wichtiges Kriterium für die Therapieentscheidung bei neu diagnostizierten hepatozellulären Karzinomen (HCC).
Susanne Krome
core +1 more source

