Results 31 to 40 of about 331,044 (287)

Barriers to primary health care: perspectives of marginalized Roma women and healthcare professionals

BMC Health Services Research
Background Marginalized Roma communities (MRCs) in Slovakia experience longstanding exclusion from essential services, including healthcare. Roma women, in particular, face compounded vulnerabilities that contribute to unequal access and poorer health ...
Jana Marosnikova Plavnicka, Zuzana Dankulincova Veselska, Daniela Filakovska Bobakova   +2 more
doaj   +1 more source

How the PJ Masks become “PJ Heroes”

Journal of Audiovisual Translation
In this study of dubbing for children, a quantitative and qualitative corpus analysis of a popular TV series were conducted. The corpus consists of 12 episodes of the animated series PJ Masks, and its corresponding Dutch (Pyjamahelden [Pyjamas heroes]) and Swedish (Pyjamashjältarna [Pyjamas heroes]) audiovisual translations.
Reglindis De Ridder, Annika Johansson
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Dominant Species Composition, Environmental Characteristics and Dynamics of Forests with Picea jezoensis Trees in Northeast China

Diversity
To describe the characteristics and dynamics of the Picea jezoensis (PJ) community, a survey of 48 forest plots containing PJ trees was conducted in Northeast China.
Jichen Duan, Zhiyuan Jia, Shusen Ge, Yutang Li, Dongwei Kang, Junqing Li   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

State of emergency care in Slovakia: a scoping review

International Journal of Emergency Medicine
Background and aim The current evidence regarding the state and evolution of emergency care (EC) in Slovakia, including the needs of both patients and healthcare personnel, remains poorly understood.
Vladimira Timkova, Pavol Mikula, Zuzana Katreniakova, Lukas Olsavsky, Iveta Nagyova   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Protective effect of pomegranate juice on retinal oxidative stress in streptozotocin-induced diabetic rats [PDF]

International Journal of Ophthalmology, 2017
AIM: To investigate the effect of pomegranate juice (PJ) intake on overall oxidation status in retinas of diabetic rats. METHODS: Twenty-seven rats were divided into four groups as control (CO), diabetic (DM), control treated with PJ (CO-PJ), and ...
Betul Tugcu, Senay Asik Nacaroglu, Asuman Gedikbasi, Mehmet Uhri, Nur Acar, Hakan Ozdemir   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Mosaic Atlas: Interview with PJ Hirabayashi [PDF]

This interview with PJ Hirabayashi, co-founder of Taiko San Jose, was conducted by Jan English-Lueck as part of the Mosaic Atlas project. PJ Hirabayashi, a third-generation Japanese American, discusses her involvement in taiko, a traditional Japanese ...
English-Lueck, Jan, Hirabayashi, PJ
core   +1 more source