Results 41 to 50 of about 1,648,019 (276)

Early assessment of treatment response in primary biliary cholangitis: key to timely management

BMC Gastroenterology
Aim The aim of our study was to explore predictive factors associated with compete biochemical response (CBR) in primary biliary cholangitis (PBC) patients treated with ursodeoxycholic acid (UDCA) at month 12 and at last check-up; CBR was defined as both
Tomas Koky, Sylvia Drazilova, Martin Janicko, Dominika Toporcerova, Jakub Gazda, Peter Jarcuska   +5 more
doaj   +1 more source

53 GBd PAM-4 DAC-less low-power (1.5 pJ/b) silicon integrated transmitter [PDF]

, 2019
C
Bauwelinck, Johan, Bogaert, Laurens, Lambrecht, Joris, Moeneclaey, Bart, Ossieur, Peter, Ramon, Hannes, Roelkens, Günther, Van Campenhout, Joris, Vanhoecke, Michael, Verbist, Jochem, Yin, Xin   +10 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Barriers to primary health care: perspectives of marginalized Roma women and healthcare professionals

BMC Health Services Research
Background Marginalized Roma communities (MRCs) in Slovakia experience longstanding exclusion from essential services, including healthcare. Roma women, in particular, face compounded vulnerabilities that contribute to unequal access and poorer health ...
Jana Marosnikova Plavnicka, Zuzana Dankulincova Veselska, Daniela Filakovska Bobakova   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

How the PJ Masks become “PJ Heroes”

Journal of Audiovisual Translation
In this study of dubbing for children, a quantitative and qualitative corpus analysis of a popular TV series were conducted. The corpus consists of 12 episodes of the animated series PJ Masks, and its corresponding Dutch (Pyjamahelden [Pyjamas heroes]) and Swedish (Pyjamashjältarna [Pyjamas heroes]) audiovisual translations.
Reglindis De Ridder, Annika Johansson
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

State of emergency care in Slovakia: a scoping review

International Journal of Emergency Medicine
Background and aim The current evidence regarding the state and evolution of emergency care (EC) in Slovakia, including the needs of both patients and healthcare personnel, remains poorly understood.
Vladimira Timkova, Pavol Mikula, Zuzana Katreniakova, Lukas Olsavsky, Iveta Nagyova   +4 more
doaj   +1 more source

Dominant Species Composition, Environmental Characteristics and Dynamics of Forests with Picea jezoensis Trees in Northeast China

Diversity
To describe the characteristics and dynamics of the Picea jezoensis (PJ) community, a survey of 48 forest plots containing PJ trees was conducted in Northeast China.
Jichen Duan, Zhiyuan Jia, Shusen Ge, Yutang Li, Dongwei Kang, Junqing Li   +5 more
doaj   +1 more source

Protective effect of pomegranate juice on retinal oxidative stress in streptozotocin-induced diabetic rats [PDF]

International Journal of Ophthalmology, 2017
AIM: To investigate the effect of pomegranate juice (PJ) intake on overall oxidation status in retinas of diabetic rats. METHODS: Twenty-seven rats were divided into four groups as control (CO), diabetic (DM), control treated with PJ (CO-PJ), and ...
Betul Tugcu, Senay Asik Nacaroglu, Asuman Gedikbasi, Mehmet Uhri, Nur Acar, Hakan Ozdemir   +5 more
doaj   +1 more source