Results 161 to 170 of about 194,517 (249)

Understanding Aging Genes and Pathways: Insight from Yeast. [PDF]

Curr Issues Mol Biol
Taormina G, Mirisola MG.
europepmc   +1 more source

Selective Cell‐Repellent 3D Scaffold Platform for Proton Radiobiology

Advanced NanoBiomed Research, EarlyView.
A selective cell‐repellent 3D scaffold platform is developed to minimize unwanted 2D cell populations surrounding engineered cell microenvironments. The approach is based on the combination of Lipidure coatings with two‐photon polymerized scaffolds and enables specific characterization of glioblastoma cells’ response to proton irradiation.
Novinda S. Pertiwi, Qais Akolawala, Rob van den Akker, Anggraeini Puspitasari‐Kokko, Henri H. Versteeg, Araci M. R. Rondon, Angelo Accardo   +6 more
wiley   +1 more source

An IscS Persulfide Donates the Sulfur for Ribosomal Protein uL16 Thioamidation

Angewandte Chemie, EarlyView.
YcaO‐catalyzed thioamidation of the ribosomal subunit protein uL16 is widespread in Pseudomonadota bacteria. We identify the iron–sulfur cluster cysteine desulfurase IscS as the sulfur donor via an IscS persulfide and observe direct IscS–uL16 interactions.
Yanqing Xue, Markus W. Voehler, Douglas A. Mitchell   +2 more
wiley   +2 more sources

Protein Titration Benchmark of CHARMM36, Amber99sb-ildn, Amber14sb, OPLS-AA/M, and Martini 2 Force Fields for Constant pH Molecular Dynamics in GROMACS. [PDF]

J Chem Theory Comput
Aho N.
europepmc   +1 more source

Antagonistic TGR5 and FXR Signaling Shapes STAT1-Dependent Interferon Responses in Intestinal Epithelial Cells. [PDF]

Cells
Jia H, Wu N, Yan Y, Kong F.
europepmc   +1 more source

Redshifting TADF Emission With a Bora‐Triptycene Lewis Acid

Angewandte Chemie, EarlyView.
Bathochromic emission shifting of donor–acceptor and multi‐resonant TADF emitters is achieved by adduct formation with a thia‐bora‐triptycene Lewis acid. TADF properties are retained on adduct formation whilst delivering > 100 nm redshift of the emission.
Mathew J. Cross, Emily L. Hanover, Arnaud Osi, Eli Zysman‐Colman, Michael J. Ingleson   +4 more
wiley   +2 more sources

6-Gingerol Potentiates β-Cell Insulin Secretion Without Acting as an L-Cell GLP-1 Secretagogue. [PDF]

Int J Mol Sci
Intisang V, Yameephai P, Uppakara K, Pathomthongtaweechai N.   +3 more
europepmc   +1 more source

An Alkali Amide Approach to Triphosphabenzenes

Angewandte Chemie, EarlyView.
Alkali metal amides offer a simple route to phosphorus aromatics. LiNMe2 catalyzes [2+2+2] cyclotrimerization of a phosphaalkyne, while tetrahydrofuran (THF) stabilizes a λ4‐triphosphabenzene anion intermediate. Using KN(SiMe3)2 switches reactivity to arene C(sp3)─H activation, giving benzylated λ4‐triphosphabenzenes and rare λ5‐triphosphabenzenes ...
Owen J. Jones, Andrew D. Bond, Ruth L. Webster   +2 more
wiley   +2 more sources

Mitochondrial defects in the cAMP-PKA-DRP1 pathway in a Crppa deletion model of dystroglycanopathy. [PDF]

Dis Model Mech
Luo J, Liu Y, Song D, Yang S, Fu X, Ge L, Wei C, Cui L, He Y, Xu J, Shen Q, Guo Y, Kanagawa M, Toda T, Wang J, Zhang H, Xiong H.   +16 more
europepmc   +1 more source

Proton‐Induced Perthionitrite‐Mediated Zinc Thiolate Persulfidation

Angewandte Chemie, EarlyView.
A thiolate‐supported zinc thionitrite complex reacts with S8 to insert sulfur at both Zn–S bonds. Although SNO− persulfidation to SSNO− is facile, thiolate persulfidation is less favored in comparison. These thermodynamic differences between S–S‐containing moieties are also observed for free perthiolate and SSNO− anions.
Madeline N. Riffel, Oluwafemi O. Ishola, Allen G. Oliver, Emily Y. Tsui   +3 more
wiley   +2 more sources