Results 171 to 180 of about 191,349 (283)

Flavin Catalysts in Organic Synthesis

Angewandte Chemie, EarlyView.
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley   +2 more sources

Cyclic AMP-dependent PKA phosphorylates starfish sperm proteins during acrosome reaction

Open Life Sciences, 2007
Sadiqul Islam M., Hoshi Motonori, Matsumoto Midori   +2 more
doaj   +1 more source

Mechanistic Insights Into the Anti-Constipation Potential of Xiaogan Jianwei Formula: Integration of HPLC-Q-TOF MS/MS, Network Pharmacology, In Vivo Validation, and Gut Microbiota. [PDF]

Biomed Chromatogr
Li T, Wang Y, Du B, Mao J, Liu S, Wu S, Ye Q, Lin N, Wu S, Lei H, Zhang X.   +10 more
europepmc   +1 more source

Deprotonation and Alkylation of Weakly Acidic C(sp3)─H Bonds Through In Situ Generation of a Strong Hydride Base From 1,1,3,3‐Tetramethyldisiloxane and Potassium tert‐Butoxide

Angewandte Chemie, EarlyView.
The use of 1,1,3,3‐tetramethyldisiloxane (TMDSO) and potassium tert‐butoxide enables direct alkylation of weakly acidic carbon–hydrogen bonds with alkyl halides. Experimental and computational studies support the formation of a substrate‐associated hydride‐like base, providing a single‐step alternative to the classical deprotonation and electrophile ...
Piers St. Onge, Brandon White, Han Yao, Travis Dudding, Stephen G. Newman   +4 more
wiley   +2 more sources

Regulation of Translation by PKA Signaling Pathway. [PDF]

Int J Mol Sci
Yang L, Hou K, Qi H.
europepmc   +1 more source

CO2‐to‐CO Electrochemical Conversion With an Fe(I) Porphyrin Complex in Water

Angewandte Chemie, EarlyView.
Using in situ UV–vis/IR spectroelectrochemistry, we track CO2 reduction by a water‐soluble iron porphyrin. Rather than the usual [Fe0] intermediate in organic solvents, CO2 binds the electrogenerated [FeI] species and undergoes reductive C─O cleavage to stable [FeII‐CO]. This previously unexplored reaction pathway is facilitated by an aqueous H‐bonding
Andrew Howe, Aude Salamé, Ulysse Garnier, Marc Robert, Elodie Anxolabéhère‐Mallart, Mun Hon Cheah   +5 more
wiley   +2 more sources

pKa engineering of a near-infrared fluorescent probe for sensitive imaging of oxidative stress in atherosclerotic plaques. [PDF]

Smart Mol
Yu Q, Liang J, Zhou T, Chen Q, Yan X, Zheng Z, Wang H, Liu J, Dong Y, Zhu WH, Wang Q.   +10 more
europepmc   +1 more source

Electrocatalytic Polarity Inversion of Azlactones: Access to α‐Quaternary Amino Acids with Electron‐Rich SOMOphiles

Angewandte Chemie, EarlyView.
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez, David Buedo, Alberto Vega‐Peñaloza, Kian Gosling, Stuart C. D. Kennington, Bart Limburg, Xavier Companyó   +6 more
wiley   +2 more sources

Water, Alcohols, Amines, and Amides as Formal Hydrogen‐Atom‐Transfer Reagents Through Activation With Redox‐Active Lewis Acids

Angewandte Chemie, EarlyView.
Protic molecules containing strong O─H or N─H bonds typically resist hydrogen‐atom abstraction because of the high reactivity of the resulting heteroatom‐centered radicals. However, association of the protic molecules with redox‐active Lewis acids can provide powerful hydrogen‐atom donors or proton‐coupled‐electron‐transfer reagents.
Petra Vojáčková, Armido Studer
wiley   +2 more sources

One‐Pot Synthesis of Aqueous PEDOT‐Based Conductive Inks via Sequential RAFT/Oxidative Polymerization

Angewandte Chemie, EarlyView.
We developed a fast, aqueous one‐pot synthesis for PEDOT:PSTFSI, combining sequential reversible addition–fragmentation chain‐transfer (RAFT) and oxidative polymerization. This method eliminates toxic solvents and purification steps, achieving full monomer conversion in under 3 h.
Fantine Negny, Melanie Bousquet, Benjamin Cabannes‐Boué, Pierre‐Yves Dugas, Lionel Hirsch, Thiago R. Guimaraes, Eric Cloutet   +6 more
wiley   +2 more sources