Results 191 to 200 of about 147,183 (245)

PKA activation rescues myocardial injury elicited by silica nanoparticles through improving oxidative stress, mitochondrial health, and copper homeostasis. [PDF]

Mater Today Bio
Guo C, Zhao X, Zhu Y, Chen M, Li Y.
europepmc   +1 more source

Clonidine protects rat hippocampal and cortical neurons from oxygen-glucose deprivation and reoxygenation-induced injury through HCN Channels. [PDF]

Sci Rep
Wang K, Yan WJ, Li G, Liu J, Chen Y, Li ZC, He Z.   +6 more
europepmc   +1 more source

Sperm capacitation in bulls, rams, bucks, and boars: molecular mechanisms and species-specific differences. [PDF]

Front Vet Sci
Kaya A, Murray R, Bodu M, Hitit M, Memili E.   +4 more
europepmc   +1 more source

Activation of the TGR5/cAMP/PKA/CREB axis in cholangiocytes mediates epithelial-mesenchymal transition and fibrosis in hepatolithiasis. [PDF]

Biol Direct
Tang D, Yang J, Shi X, Gu X, Zhao L.
europepmc   +1 more source

Magnesium film-over-nanospheres (FONs) for surface-enhanced Raman scattering.

Faraday Discuss
Ten A, Lomonosov V, Pehlivan ZS, Ringe E.   +3 more
europepmc   +1 more source

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A Structural Comparison of Inhibitor Binding to PKB, PKA and PKA-PKB Chimera

Journal of Molecular Biology, 2007
Although the crystal structure of the anti-cancer target protein kinase B (PKBbeta/Akt-2) has been useful in guiding inhibitor design, the closely related kinase PKA has generally been used as a structural mimic due to its facile crystallization with a range of ligands.
Ian Collins
exaly   +3 more sources

Dynamics of signaling by PKA

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005
The catalytic and regulatory subunits of cAMP-dependent protein kinase (PKA) are highly dynamic signaling proteins. In its dissociated state the catalytic subunit opens and closes as it moves through its catalytic cycle. In this subunit, the core that is shared by all members of the protein kinase family is flanked by N- and C-terminal segments.
Susan S, Taylor, Choel, Kim, Dominico, Vigil, Nina M, Haste, Jie, Yang, Jian, Wu, Ganesh S, Anand   +6 more
openaire   +2 more sources

PKA-Dependent and PKA-Independent Pathways for cAMP-Regulated Exocytosis

Physiological Reviews, 2005
Stimulus-secretion coupling is an essential process in secretory cells in which regulated exocytosis occurs, including neuronal, neuroendocrine, endocrine, and exocrine cells. While an increase in intracellular Ca2+concentration ([Ca2+]i) is the principal signal, other intracellular signals also are important in regulated exocytosis. In particular, the
Susumu, Seino, Tadao, Shibasaki
openaire   +2 more sources

Standardization of prekallikrein activator (PKA): the 1st International Standard for PKA

British Journal of Haematology, 1985
SummaryA international collaborative study was carried out to establish an international standard for prekallikrein activator (PKA). The candidate material, coded 82/530, was assayed against the Office of Biologics (FDA) PKA reference preparation No. 2 (OoB 2) and the 1st British Reference Preparation for PKA.
P J, Kerry, A D, Curtis, D P, Thomas
openaire   +2 more sources