Results 31 to 40 of about 23,446 (211)

EKSISTENSI LEKRA DALAM PUSARAN MANIFESTO KEBUDAYAAN DEMOKRASI TERPIMPIN

Istoria, 2022
Demokrasi Terpimpin merupakan sistem demokrasi yang berlangsung setelah Dekrit Presiden 5 Juli 1959. Diterapkannya sistem ini menyebabkan kekuasaan Soekarno bersifat mutlak, karena segala keputusan berada di tangan presiden.
Cici Widariyanti
doaj   +1 more source

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, EarlyView.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source

Characterization of inflammatory pseudotumors in a large animal model of liver cancer

Animal Models and Experimental Medicine, EarlyView.
CT images in arterial and portal venous phases of liver lesions in Oncopig. Abstract Background The development of relevant and robust large animal models of hepatocellular carcinoma is needed to test new therapeutic strategies for this disease. Transgenic approaches hold promise in addressing this complex problem. One such model, the Oncopig, has been
Erik N. K. Cressman, Samantha Hicks, Natalie W. Fowlkes, Danielle L. Stolley, Maria Sophia Stenkamp   +4 more
wiley   +1 more source

PB-PKI: A Privacy-aware Blockchain-based PKI

International Conference on Security and Cryptography, 2017
Conventional public-key infrastructure (PKI) designs using certificate authorities and web-of-trust are not optimal and have security flaws. The properties afforded by the Bitcoin blockchain are a natural solution to some of the problems with PKI - in ...
Louise Axon, M. Goldsmith
semanticscholar   +1 more source

Human vs. artificial intelligence: Physicians outperform ChatGPT in real‐world pharmacotherapy counselling

British Journal of Clinical Pharmacology, EarlyView.
Aims To assess the utility of the artificial intelligence (AI) chatbot ChatGPT (openly available version 3.5) in responding to real‐world pharmacotherapeutic queries from healthcare professionals. Methods Three independent and blinded evaluators with different levels of medical expertise and professional experience (beginner, advanced, and expert ...
Benjamin Krichevsky, Stefan Engeli, Stefanie M. Bode‐Böger, Felix Koop, Martin Schulze Westhoff, Sebastian Schröder, Carsten Schumacher, Thorben Pape, Dirk O. Stichtenoth, Johannes Heck   +9 more
wiley   +1 more source

Molecular Recognition of FDA-Approved Small Molecule Protein Kinase Drugs in Protein Kinases

Molecules, 2022
Protein kinases are key enzymes that catalyze the covalent phosphorylation of substrates via the transfer of the γ-phosphate of ATP, playing a crucial role in cellular proliferation, differentiation, and various cell regulatory processes.
Yan Zhu, Xiche Hu
doaj   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Toward a global repository of insect traits (GRIT)

Insect Conservation and Diversity, EarlyView.
Biodiversity loss is accelerating, yet insect conservation is hindered by the absence of a centralised, comprehensive trait database. We propose the GRIT, a FAIR, open‐access platform uniting datasets and collaborators worldwide. GRIT will harness advanced computational tools for trait acquisition and imputation, enabling large‐scale ecological ...
Pedro Cardoso, Nathan Jay Baker, Mário Boieiro, Dries Bonte, Paulo A. V. Borges, Michael F. Braby, Vasco Branco, Dragan Chobanov, Luis Correia, Daniel T. Dalton, Mariana Damas‐Mora, Raphael K. Didham, Lynne Forster, Richard Glatz, Jacob A. Gorneau, Axel Hochkirch, Ameli Kirse, Elinor M. Lichtenberg, Nuria Macías‐Hernández, Marija Miličić, Melinda Moir, Pablo Moreno‐García, Ruth Neessen, Jorge Ari Noriega, Clint A. Penick, Kayla I. Perry, James Pryke, Carla Rego, Karl A. Roeder, Stéphanie Saussure, Vaughn Shirey, Pasi Sihvonen, Ilja Svetnik, Sergei Tarasov, Pedro Trindade, Ellen A. R. Welti, Mark Wong, Christoph Scherber   +37 more
wiley   +1 more source

JEJAK MARXISME DI INDONESIA

Jurnal Yaqzhan: Analisis Filsafat, Agama dan Kemanusiaan, 2017
Pada akhir abad ke-19 paham liberalisme ekonomi ala Barat terdengar gaungnya oleh pemerinah Hindia-Belanda. Paham itu mengubah kebijakan ekonomi pemerintah dari yang semula kerja paksa menjadi industrialisasi.
Ahmad Syatori
doaj  

A QSAR Study of HIV Protease Inhibitors Using Computational Descriptors to Prediction of pki of Cycle Derivatives of Urea

Bihdād, 2020
Preventing and reducing the spread of HIV (HIV) has always been a concern in medical science. One of the most common ways to control the virus is using enzyme-blocking drugs. In this study, we attempted to predict the biological activity (PKi) of organic
Zakiyeh Bayat, Samaneh Mohamad Ebrahimzadeh Sepasgozar   +1 more
doaj