Results 41 to 50 of about 9,792 (172)

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Bina damai dalam hubungan muhammadiyah dan pki di kota gede 1950-1965

open access: yes, 2022
Prinsip-prinsip bina damai banyak terdapat ajaran islam.Menurut wahiduddin khan,terdapat ayat al-quran yang menganjurkan diri dari konflik dan permusuhan (Non-violence and peace-building in islam ,2017).Tetapi dalam dalam praktiknya,hal tersebut tidak ...
Luqman hakim, Zakiya Darojat
core  

Molecular Recognition of FDA-Approved Small Molecule Protein Kinase Drugs in Protein Kinases

open access: yesMolecules, 2022
Protein kinases are key enzymes that catalyze the covalent phosphorylation of substrates via the transfer of the γ-phosphate of ATP, playing a crucial role in cellular proliferation, differentiation, and various cell regulatory processes.
Yan Zhu, Xiche Hu
doaj   +1 more source

Controlling Structures and Properties of NaCl‐Containing Alginate/Polyacrylamide Tough Hydrogels via a One‐Pot Process

open access: yesChemistry – A European Journal, EarlyView.
NaCl‐incorporated alginate/polyacrylamide tough hydrogels are prepared through a facile one‐pot strategy that enables direct ion incorporation during network formation. Compared with conventional soaking, this approach reduces diffusion‐limited ion gradients and provides a more spatially consistent ion distribution.
Taeuk Eom   +6 more
wiley   +1 more source

Enhancing Lentiviral Purification: Combining CIM QA Monolithic Columns With Design of Experiments Approach

open access: yesELECTROPHORESIS, EarlyView.
Lentiviral vector purification using QA CIM monolith anion‐exchange chromatography was optimized via 96‐well and DOE, increasing recovery from 20% to 90%. The process achieved 3.3‐log host cell protein reduction, decreased particle impurities, and showed high binding capacity, supporting large‐scale manufacturing.
Luka Bevc   +7 more
wiley   +1 more source

Status of ash (Fraxinus spp.) in mixed hardwood post‐outbreak forests near the epicentre of the emerald ash borer invasion

open access: yesAgricultural and Forest Entomology, EarlyView.
The persistence and health of ash populations were characterized in post‐outbreak forests near the epicentre of the emerald ash borer (EAB) invasion in North America. Regenerating ash remained abundant, but densities of understory ash were higher in wetlands (hydric), while ash remained at the seedling stage in riparian (mesic) and upland (xeric ...
Aaron Tayal, Kayla I. Perry
wiley   +1 more source

Seeing change through others' eyes: Meta‐beliefs and willingness to participate in a restorative programme in prison

open access: yesLegal and Criminological Psychology, EarlyView.
Abstract Purpose The present study examines whether incarcerated individuals' meta‐malleability, the belief that others perceive them as capable of change, predicts support for restorative justice (RJ), and which emotional mechanisms moderate this influence.
Inbal Peleg‐Koriat   +2 more
wiley   +1 more source

Human and AI judgements of restorative responses to sexual abuse: The role of perceived severity

open access: yesLegal and Criminological Psychology, EarlyView.
Abstract Purpose Restorative justice (RJ) offers an alternative or complement to criminal justice in sexual abuse cases, yet the public remains ambivalent. Given that survivors increasingly turn to large language models (LLMs) for information and support when coping with sensitive justice‐related decisions, the present study examined whether the ...
Inbal Peleg‐Koriat, Kfir Asraf
wiley   +1 more source

A QSAR Study of HIV Protease Inhibitors Using Computational Descriptors to Prediction of pki of Cycle Derivatives of Urea

open access: yesBihdād, 2020
Preventing and reducing the spread of HIV (HIV) has always been a concern in medical science. One of the most common ways to control the virus is using enzyme-blocking drugs. In this study, we attempted to predict the biological activity (PKi) of organic
Zakiyeh Bayat   +1 more
doaj  

Kinematic‐calcium loops unravel impaired excitation–contraction coupling in MELAS‐affected cardioids

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Representation of kinematic and calcium transient loop with respect to traditional time coplotting. Abstract Impaired Ca2+ handling, and in particular leakage from the sarcoplasmic reticulum, is a critical mechanism in metabolic diseases affecting the heart.
Margherita Burattini   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy