Results 71 to 80 of about 23,446 (211)

Deleterious association between proton pump inhibitor and protein kinase inhibitor exposure and survival for patients with lung cancer: A nationwide cohort study

Cancer Treatment and Research Communications
Introduction: Previous studies have identified an interaction between protein kinase inhibitors (PKIs) and proton pump inhibitors (PPIs) in patients with lung cancer. This type of interaction may reduce the efficacy of PKIs.
Constance Bordet, Mahmoud Zureik, Yoann Zelmat, Margaux Lafaurie, Maryse Lapeyre-Mestre, Agnès Sommet, Julien Mazieres, Fabien Despas   +7 more
doaj   +1 more source

Cytotoxic Effect of the Her-2/Her-1 Inhibitor PKI-166 on Renal Cancer Cells Expressing the Connexin 32 Gene

Journal of Pharmacological Sciences, 2005
We have reported that connexin (Cx) 32 acts as a tumor suppressor gene in renal cancer cells partly due to Her-2 inactivation. Here, we determined if a Her-2/Her-1 inhibitor (PKI-166) can enhance the tumor-suppressive effect of Cx32 in Caki-2 cells from ...
Eriko Fujimoto, Tomohiro Yano, Hiromi Sato, Kiyokazu Hagiwara, Hiroshi Yamasaki, Sumiko Shirai, Keiko Fukumoto, Hiromi Hagiwara, Etsuko Negishi, Koichi Ueno   +9 more
doaj   +1 more source

Structure‐Guided Identification and Evaluation of Epalrestat and Ranirestat‐Like Compounds Against Aldose Reductase: Therapeutic Management of Diabetic Neuropathy

ChemistryOpen, Volume 14, Issue 12, December 2025.
Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan, Dharmendra Kumar Yadav, Moyad Shahwan, Anas Shamsi   +3 more
wiley   +1 more source

Cross-domain identity authentication scheme based on blockchain and PKI system

High-Confidence Computing, 2022
Hai Zhang, Fengqun Zhao
semanticscholar   +1 more source

Model for PKI interoperability in Serbia / Модель доверия и архетектура PKI в Республике Сербия / Model za PKI interoperabilnost u Republici Srbiji

Vojnotehnički Glasnik, 2017
The increasing use of electronic services that use electronic certificates and the increasing implementation of public key infrastructures require their interconnection and interoperability.
Radomir I. Prodanović, Ivan B. Vulić
doaj   +1 more source

A Non-imaging High Throughput Approach to Chemical Library Screening at the Unmodified Adenosine-A3 Receptor in Living Cells

Frontiers in Pharmacology, 2017
Recent advances in fluorescent ligand technology have enabled the study of G protein-coupled receptors in their native environment without the need for genetic modification such as addition of N-terminal fluorescent or bioluminescent tags.
Maria Augusta Arruda, Maria Augusta Arruda, Maria Augusta Arruda, Leigh A. Stoddart, Leigh A. Stoddart, Karolina Gherbi, Karolina Gherbi, Stephen J. Briddon, Stephen J. Briddon, Barrie Kellam, Stephen J. Hill, Stephen J. Hill   +11 more
doaj   +1 more source

PERANAN SURAT KABAR SOERAPATI DALAM PERLAWANAN INTELEKTUAL PRIBUMI DI JAWA BARAT TAHUN 1923-1925

Patanjala: Jurnal Penelitian Sejarah dan Budaya, 2016
Abstrak Perlawanan intelektual pribumi yang dilakukan oleh organisasi berideologi komunis menggunakan beberapa media, diantaranya surat kabar Soerapati. Metode yang digunakan adalah metode sejarah yang terdiri atas empat tahapan kerja: heuristik, kritik,
Dharyanto Tito Wardani
doaj   +1 more source

Unified Identity Authentication Scheme of System Wide Information Management Based on SAML-PKI-LDAP

, 2022
Zhijun Wu, Zhuoning Bai, Lizhe Zhang, Kenian Wang   +3 more
openalex   +1 more source

Supplemental Table 7 from First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer

, 2023
Geoffrey I. Shapiro, Katherine M. Bell‐McGuinn, Julian R. Molina, Johanna C. Bendell, James Spicer, Eunice L. Kwak, Susan Pandya, Robert Millham, Gary Borzillo, Kristen J. Pierce, Lixin Han, Brett E. Houk, Jorge D. Gallo, María Alsina, Irene Braña, Josep Tabernero   +15 more
openalex   +2 more sources

Triskelion—In Pursuit of Proficiency Through Immersive Gameplay

Information
As technology advances, interest in video games is extending to broader audiences. This makes gamification as a mechanism for improving educational outcomes increasingly attractive.
Victor Winter
doaj   +1 more source