Results 111 to 120 of about 14,270 (217)

Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis

open access: yesDrug Design, Development and Therapy, 2020
Peng Gao,1,2 Shuo Shen,1,2 Xiaodong Li,3 Dandan Liu,1,2 Yuqing Meng,1,2 Yanqing Liu,1,2 Yongping Zhu,1,2 Junzhe Zhang,1,2 Piao Luo,1,2 Liwei Gu1,2 1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, People ...
Gao P   +9 more
doaj  

PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation [PDF]

open access: gold, 2015
Valeria Iansante   +12 more
openalex   +1 more source

PKM2 regulates metabolic flux and oxidative stress in the murine heart

open access: yesPhysiological Reports
Cardiac metabolism ensures a continuous ATP supply, primarily using fatty acids in a healthy state and favoring glucose in pathological conditions. Pyruvate kinase muscle (PKM) controls the final step of glycolysis, with PKM1 being the main isoform in ...
Katie C. Y. Lee   +7 more
doaj   +1 more source

MOESM1 of PKM2, function and expression and regulation

open access: yes, 2019
Additional file 1: Table S1. PKM2 related GO terms and KEGG pathways in cancer tissue. GO terms and KEGG pathways with P-valuesâ <â 0.05 were considered statistically significant. GO: Gene Ontology. KEGG: Kyoto Encyclopedia of Genes and Genomes.
Zhang, Ze   +5 more
openaire   +1 more source

PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation [PDF]

open access: gold, 2016
Min Xie   +12 more
openalex   +1 more source

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