Prophylactic dexamethasone at the time of absolute lymphocyte expansion does not mitigate risk or event-free survival for immune effector cell associated delayed neurotoxicity. [PDF]
Lim KJ +27 more
europepmc +1 more source
Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity
ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette +5 more
wiley +1 more source
Heterologous expression of NRPS and PKS pathways in Escherichia coli: from bottlenecks to biosynthetic platforms. [PDF]
Göbner L, Gulder TAM, D'Agostino PM.
europepmc +1 more source
Photoreactive Pantetheinyl Mimics Reveal Design Limitations for Crypto‐Acyl Carrier Proteins
Probes were rationally designed to capture key intramolecular interactions thorugh photocrosslinking in thiotemplated assembly lines: polyketide synthases (PKS), fatty acid synthases (FAS), and non‐ribosomal peptide synthetases (NRPS). Poor or no crosslinking was observed from these probes, highlighting current limitations of synthetic and structural ...
Anna‐Kay R. West +6 more
wiley +1 more source
Exploring rare coumarins biosynthesis by Gloeophyllum trabeum: an integrated computational genomics, molecular docking and spectroscopic approach. [PDF]
Al-Salihi SAA +3 more
europepmc +1 more source
Extending the starter-unit selection of a collaborating non-reducing polyketide synthase through rational domain swaps. [PDF]
Yin R +7 more
europepmc +1 more source
TridentSynth: a webtool for the retrosynthesis of molecules using chimeric type I polyketide synthases and chemoenzymatic pathways. [PDF]
Chainani Y +10 more
europepmc +1 more source
Intra- and inter-biosynthetic gene cluster allelic variation as drivers of chemical diversification in Streptomyces. [PDF]
Nayeb G Hosseini G, Barona-Gómez F.
europepmc +1 more source
Comparative genomics reveals the evolution of anthraquinone biosynthesis in Polygonaceae. [PDF]
Cheng Q, Meng F, Yang X, Song X, Chen W.
europepmc +1 more source

