Results 201 to 210 of about 34,815 (260)

Harnessing Dual Power: Genistein-Loaded Pumpkisomes in Pullulan Microneedles for Potent Antioxidant and Anticancer Therapy Against Ehrlich Ascites Carcinoma and Breast Cancer Cells. [PDF]

Pharmaceutics
Elhabal SF, S Shoela M, Elrefai MFM, E Hassan F, Morsy SAA, Younis Abdelgawad W, K Ali S, M Mohie P, M Elsharkawy A, Ewedah TM, Mousa IS, Fouad MA, Allam S, Hamdan AME.   +13 more
europepmc   +1 more source

KRASG12R-Mutant Pancreatic Cancer Features Limited ERK/MAPK Transcriptional Activity and a Distinctive Tumor Microenvironment. [PDF]

Cancer Res
Burge RA, Le Roux O, Popow O, Spadafora VK, Rajesh C, Adair SJ, Bialousow L, Murphy C, Saberi S, Vaena SG, Taquey MC, Allen S, Han L, Helke KL, Sharma S, Ostrowski MC, Guttridge DC, Dincman TA, Bauer TW, Kashatus DF, McFall T, Haigis KM, Hollingsworth MA, Counter CM, Der CJ, Hobbs GA.   +25 more
europepmc   +1 more source

PK-PD

Farumashia, 2012
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Targeting DNA-PK

2023
This chapter explores the multifaceted roles of DNA-PK with particular focus on its functions in non-homologous end-joining (NHEJ) DNA repair. DNA-PK is the primary orchestrator of NHEJ but also regulates other biologic processes. The growing understanding of varied DNA-PK biologic roles highlights new avenues for cancer treatment.
Jan Philipp, Novotny, Adrian, Mariño-Enríquez, Jonathan A, Fletcher   +2 more
openaire   +2 more sources

Improvement of Pk-Anonymization

2014 IEEE 33rd International Symposium on Reliable Distributed Systems Workshops, 2014
Pk-anonymization is a data anonymization method that employs randomization. Pk-anonymization guarantees Pk-anonymity, which is an extension of probabilistic k-anonymity. To implement this method, we assign random noise to records to reduce the probability of identifying record owners to less than 1/k.
Miho Kakizawa, Chiemi Watanabe, Ryo Furukawa 0003, Tsubasa Takahashi 0001   +3 more
openaire   +1 more source

Liver pyruvate kinase (PK) isozymes in a PK‐deficient patient*

Annals of Human Genetics, 1968
SUMMARYLiver from a patient with hereditary haemolytic anaemia due to pyruvate kinase deficiency is a deficient in the ‘erythrocyte’ PK isozyme as are her erythrocytes. The chromatographic, electrophoretic, antigenic, heat stability and kinetic properties of the patient's enzyme were not different from normal.
R H, Bigley, R D, Koler
openaire   +2 more sources

Two homozygous cases of erythrocyte pyruvate kinase (PK) deficiency in Japan: PK sendai and PK shinshu

American Journal of Hematology, 1988
AbstractTwo new erythrocyte pyruvate kinase (PK) variants with severe nonspherocytic hemolytic anemia are presented. These cases are both considered to be homozygous because of the consanguineous marriages in their parents. Their erythrocyte PK's were characterized by the recommended methods of the International Committee for Standardization in ...
Kenzaburo Tani, Hisaichi Fujii, Keisuke Takahashi, Hiromi Ogura, Hitoshi Kanno, Kiyoshi Hayasaka, Kuniaki Narisawa, Tatsutoshi Nakahata, Taro Akabane, Takayuki Morisaki, Hisashi Tsutsumi, Shiro Miwa   +11 more
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Determination of pK's of trinucleotides

Biopolymers, 1972
AbstractpK's of trinucleotides are calculated according to the theory of Kirkwood and Westheimer for ellipsoids. In order to compare the calculated values with some experimental results, a number of trimers were prepared and their pK's were measured.
openaire   +2 more sources