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[Pharmacokinetics (PK) of mAbs].
Medecine sciences : M/S, 2009 The human Fc portion of humanized monoclonal antibodies (mAb) gives them a half-life of around 21 days, similar to that of endogenous immunoglobulin G (IgG). Neonatal Fc receptor (FcRn) plays a major role in the pharmacokinetics (PK) of mAbs. By protecting them from degradation, it is responsible for their long half-life and by allowing their ...openaire +2 more sourcesPK
2010 R. Hamish McAllister-Williams, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Linda P. Spear, Tim C. Kirkham, Thomas Steckler, Delphine Capdevielle, Jean-Philippe Boulenger, Delphine Capdevielle, Jean-Philippe Boulenger, Delphine Capdevielle, Jean-Philippe Boulenger, Cyril Höschl, Martine Cador, Ben J. Harrison, Christos Pantelis, Anthony Riley, Steve Kohut, Alex Hofer, Ben J. Harrison, Christos Pantelis, Seithikurippu R. Pandi-Perumal, D. Warren Spence, Shelby Freedman Harris, Michael J. Thorpy, Milton Kramer, Ian Stolerman, Holden D. Brown, Michael Ragozzino, Klaus A. Miczek, Anne Jackson, Sven Ove Ögren, Oliver Stiedl, Paul R. Pentel, Mark LeSage, Victoria L. Harvey, Tony Dickenson, Christine A. Franco, Marc N. Potenza, Gail Winger, Mei-Chuan Ko, James H. Woods, Matthew I. Palmatier, Rick A. Bevins, Stephan G. Anagnostaras, Jennifer R. Sage, Stephanie A. Carmack, Jos Prickaerts, Jos Prickaerts, Jos Prickaerts, Warren H. Meck, Catalin V. Buhushi, Christoph U. Correll, Ian Stolerman, Mohammed Shoaib, Trevor Robbins, Daniel Hoyer, Thomas Steckler, Linda P. Spear, Luzio Tremolizzo, Gessica Sala, Carlo Ferrarese, Seiya Miyamoto, Thomas Steckler, David S. Tait, Verity J. Brown, Richard A. Depue, Tara L. White, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Ian Stolerman, Jean-Michel Scherrmann, S. Stevens Negus, Dana E. Selley, Laura J. Sim-Selley, Christoph Hiemke, Sophie Tambour, John C. Crabbe, Pierre Baumann, Kim Wolff, Christof Baltes, Thomas Mueggler, Markus Rudin, Alan J. Budney, Robert L. Balster, Sharon Walsh, Robert L. Balster, Sharon Walsh, Robert L. Balster, Sharon Walsh, Andrea Bari, Johannes Mosbacher, Paul Willner, Klaus A. Miczek, Trevor Robbins, Wolfgang Fleischhacker, Etienne Sibille, Nicole Edgar, Sabine M. Hölter, John F. Cryan, Michel Le Moal, Marco Leyton, Sara Tomlinson, Glen Baker, Bernard Le Foll, Naheed (Max) Mirza, Tomasz Schneider, Jos Prickaerts, Jos Prickaerts, Robert L. Balster, Sharon Walsh, Yogita Chudasama, Thomas Steckler, Thomas Steckler, Daniel Hoyer, Stan Floresco, Christine A. Franco, Marc Potenza, Fabrizio Benedetti, Peter Riederer, Siegfried Hoyer, Luzio Tremolizzo, Gessica Sala, Carlo Ferrarese, Luzio Tremolizzo, Gessica Sala, Carlo Ferrarese, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Christoph Hiemke, Malcolm Lader, Stefan Leucht, Mark Slifstein, Linda P. Spear, Samuel G. Siris, Susan Jones, Peter Verheart, Per Svenningsson, Per Andrén, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, John Atack, Hilde Lavreysen, Stephen C. Fowler, Harriet de Wit, Britta Hahn, Stephen C. Fowler, Helen Cassaday, Paul Willner, Darren R. Christensen, Warren K. Bickel, Michael Minzenberg, David Baldwin, C. Neill Epperson, C. Neill Epperson, Lawrence Scahill, I. T. Uzbay, Lisiane Bizarro, Bart Ellenbroek, Linda P. Spear, Patrick D. McGorry, Alison R. Yung, Mark A. Geyer, Johannes Mosbacher, Malcolm Lader, Angela Roberts, Celia Morgan, Valerie Curran, Christine A. Franco, Marc Potenza, Celia Morgan, Valerie Curran, Thomas Steckler, Harriet de Wit, Jill B. Becker, Mary Cain, Michael T. Bardo, Thomas Steckler, Trevor Robbins, Theodora Duka, Sam Hutton, C. Neill Epperson, Celia Morgan, Valerie Curran +199 moreopenaire +1 more source
