Results 61 to 70 of about 34,815 (260)

PKS gene clusters.

open access: yes, 2019
Each PKS gene is shown along with adjacent genes in the genome. Genes are labeled with putative functions of the corresponding protein, as determined by blastp and conserved domain analysis (S2 Table, [9]). Gene orientations are indicated by direction of
Elizabeth Thomas (137168)   +5 more
core   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong   +13 more
wiley   +1 more source

Propaganda pks dalam iklan "memilih iklan pks" (analisis semiotika charles sanders peirce) [PDF]

open access: yes, 2015
Penelitian ini membahas mengenai propaganda dalam Iklan PKS “Memilih PKS”. Propaganda menjadi alat yang sering kali digunakan untuk mendapatkan suatu dukungan, misalnya dalam pemilu.
Warsita, Tiara Kresna
core  

Detected contig numbers in PKS genes or PKS domains search.

open access: yes, 2015
* Keyword search was conducted against BLAST top hit tables of all contig databases of K. mikimotoi** Domain search was performed against amino acid sequence databases of K.
Shujiro Okuda (13874)   +8 more
core   +1 more source

Prediction of Human Serum Concentration–Time Profiles of Golimumab and Ustekinumab Using Pharmacokinetic Data From Common Marmosets With Assessment of Anti‐Drug Antibodies

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
This study identified new optimal allometric scaling exponents for human PK prediction of monoclonal antibodies with linear PKs from marmoset PK data. In addition, immunogenicity in common marmosets was evaluated following the repeated dose of golimumab and ustekinumab, minimal anti‐drug antibodies were detected.
Ayaka Tajiri   +6 more
wiley   +1 more source

Clinical Impact of Maximum Plasma Concentration of Busulfan in Pediatric Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Busulfan's narrow therapeutic index and high pharmacokinetic (PK) variability warrant investigation of its exposure–toxicity relationship. We retrospectively analyzed 334 pediatric and young adult patients who underwent allogeneic hematopoietic stem cell transplantation at Seoul National University Children's Hospital between 2009 and 2020 and received
Sungyeun Bae   +7 more
wiley   +1 more source

Scope, Distribution, and Cause of the Peanut Kernel Shrivel (PKS) Syndrome: An Emerging Threat to Australia’s Peanut Industry [PDF]

open access: yes
The cause of peanut kernel shrivel (PKS) syndrome, affecting peanut crops in Australia’s growing regions, is currently unknown. It is estimated that PKS is costing the peanut industry more than AUD 5 M p.a.
Ash, Gavin J.   +5 more
core   +1 more source

JEJAK DAKWAH PARTAI KEADILAN SEJAHTERA (PKS) MEMASUKI MUHAMMADIYAH: Mencermati Kasus di Yogyakarta sebagai Fenomena Politik Dakwah

open access: yesJurnal Sosiologi Agama, 2019
Sebagai kelompok yang memiliki struktur, anggota, mekanisme organisasi serta fungsi-fungsi politik dan sosial keagamaan, Partai Keadilan Sejahtera (PKS) maupun Muhammadiyah membawa kepentingan misi dan dakwah masing-masing.
Nur Wahid
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

open access: yesEpilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola   +3 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia   +4 more
wiley   +1 more source

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