Results 1 to 10 of about 11,403 (119)

Paenitracins, a novel family of bacitracin-type nonribosomal peptide antibiotics produced by plant-associated Paenibacillus species [PDF]

mSystems
The growing threat of antimicrobial resistance necessitates the discovery of novel antibiotics with activity against drug-resistant pathogens. Members of the genus Paenibacillus are a rich source of nonribosomal peptides (NRPs), including well-known ...
Nataliia V. Machushynets, Somayah S. Elsayed, Chao Du, Vladyslav Lysenko, Mercedes de la Cruz, Pilar Sanchez, Olga Genilloud, Nathaniel I. Martin, Mark R. Liles, Gilles P. van Wezel   +9 more
doaj   +2 more sources

Actinomycetes of secondary metabolite producers from mangrove sediments, Central Java, Indonesia [PDF]

Veterinary World, 2021
Background and Aim: Actinomycetes are a group of Gram-positive bacteria with a fungus-like morphology. Their natural habitat encompasses terrestrial and water areas, including mangrove ecosystems.
Wilis Ari Setyati, Delianis Pringgenies, Nirwani Soenardjo, Rini Pramesti   +3 more
doaj   +1 more source

Diversity and antimicrobial activity of culturable actinobacteria isolated from the sediment of Sarıkum Lake

Biotechnology & Biotechnological Equipment, 2021
In this study, actinobacteria isolated from Sarıkum Lake sediment were characterized (Sinop-Turkey). A total of 48 actinobacteria were isolated using ten selective media with the dilution-plating method.
Aysel Veyisoglu, Demet Tatar
doaj   +1 more source

Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus [PDF]

Open Biology, 2017
Gliotoxin is an epipolythiodioxopiperazine (ETP) class toxin, contains a disulfide bridge that mediates its toxic effects via redox cycling and is produced by the opportunistic fungal pathogen Aspergillus fumigatus.
Stephen K. Dolan, Tobias Bock, Vanessa Hering, Rebecca A. Owens, Gary W. Jones, Wulf Blankenfeldt, Sean Doyle   +6 more
doaj   +1 more source

Genetic Relationships in the Toxin-Producing Fungal Endophyte, Alternaria oxytropis Using Polyketide Synthase and Non-Ribosomal Peptide Synthase Genes

Journal of Fungi, 2021
The legume Oxytropis sericea hosts a fungal endophyte, Alternaria oxytropis, which produces secondary metabolites (SM), including the toxin swainsonine.
Rebecca Creamer, Deana Baucom Hille, Marwa Neyaz, Tesneem Nusayr, Christopher L. Schardl, Daniel Cook   +5 more
doaj   +1 more source

Specific Neuropilins Expression in Alveolar Macrophages among Tissue-Specific Macrophages. [PDF]

PLoS ONE, 2016
In the immune system, neuropilins (NRPs), including NRP-1 and NRP-2, are expressed in thymocytes, dendritic cells, regulatory T cells and macrophages.
Naing Ye Aung, Rintaro Ohe, Hongxue Meng, Takanobu Kabasawa, Suran Yang, Tomoya Kato, Mitsunori Yamakawa   +6 more
doaj   +1 more source

Diversity of Linear Non-Ribosomal Peptide in Biocontrol Fungi

Journal of Fungi, 2020
Biocontrol fungi (BFs) play a key role in regulation of pest populations. BFs produce multiple non-ribosomal peptides (NRPs) and other secondary metabolites that interact with pests, plants and microorganisms. NRPs—including linear and cyclic peptides (L-
Xiaoyan Niu, Narit Thaochan, Qiongbo Hu
doaj   +1 more source

Identification of non-ribosomal peptide synthetase in Ganoderma boninense Pat. that was expressed during the interaction with oil palm

Scientific Reports, 2021
Basal stem rot (BSR) of oil palm is a disastrous disease caused by a white-rot fungus Ganoderma boninense Pat. Non-ribosomal peptides (NRPs) synthesized by non-ribosomal peptide synthetases (NRPSs) are a group of secondary metabolites that act as fungal ...
Neda Shokrollahi, Chai-Ling Ho, Nur Ain Izzati Mohd Zainudin, Mohd As’wad Bin Abul Wahab, Mui-Yun Wong   +4 more
doaj   +1 more source

Knowledge-guided data mining on the standardized architecture of NRPS: Subtypes, novel motifs, and sequence entanglements.

PLoS Computational Biology, 2023
Non-ribosomal peptide synthetase (NRPS) is a diverse family of biosynthetic enzymes for the assembly of bioactive peptides. Despite advances in microbial sequencing, the lack of a consistent standard for annotating NRPS domains and modules has made data ...
Ruolin He, Jinyu Zhang, Yuanzhe Shao, Shaohua Gu, Chen Song, Long Qian, Wen-Bing Yin, Zhiyuan Li   +7 more
doaj   +1 more source

Effect of growth medium composition on the efficiency of non-ribosomal synthesis in bacteria of the genus Bacillus [PDF]

BIO Web of Conferences
Bacteria of the genus Bacillus are known for their ability to suppress a wide range of pathogenic microflora through the production of a variety of secondary metabolites, a significant proportion of which are non-ribosomal peptides.
Vibe Valeria, Kulikov Maxim, Prazdnova Evgeniya, Mazanko Maria, Chistyakov Vladimir, Rudoy Dmitry, Shevchenko Viktoriya, Kulikova Natalya   +7 more
doaj   +1 more source