Results 91 to 100 of about 5,637,228 (331)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Impact of the Four-Dimensional Components of Place Attachment on Students' Place Satisfaction with the University (Case Study: Faculty of Engineering at Ayatollah Boroujerdi University) [PDF]

توسعه پایدار شهری
Despite the significance of place attachment for university students, due to its impacts on academic performance, emotional well-being, and interpersonal relationships, no research has yet been conducted on the relationship between the four components of
Sepideh Paymanfar
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Perceived Visitor Impacts of Cultural Heritage Tourism: The Role of Place Attachment in Memorable Visitor Experiences.

, 2022
This chapter is the first to develop and propose a single integrative model exploring associations between visitors’ perceived positive impacts of cultural heritage tourism, cultural heritage place attachment (with sub-dimensions of cultural place ...
Ramkissoon, Haywantee
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Constructing Geographical Place Attachment in Ritual Tourism of Cities (Yom al-Abbas Ceremony in Zanjan) [PDF]

International Journal of Tourism, Culture and Spirituality
Ritual tourism, as a reflection of local identity and culture, plays a significant role in shaping and renewing the tourism experience. This study aims to explain the effect of ritual tourism (with emphasis on the Yom al-Abbas ceremony in Zanjan) on the ...
Alireza Daviran
doaj   +1 more source

Density-dependent, central-place foraging in a grazing herbivore: competition and tradeoffs in time allocation near water [PDF]

, 2015
Optimal foraging theory addresses one of the core challenges of ecology: predicting the distribution and abundance of species. Tests of hypotheses of optimal foraging, however, often focus on a single conceptual model rather than drawing upon the ...
Medill, SA, Richard, E, Uzal, A, McLoughlin, PD, Rozen-Rechels, D, van Beest, FM   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Frame analysis, place perceptions and the politics of natural resource management [PDF]

, 2008
This thesis is an exploration into the politics of natural resource management. An objective is to integrate concerns for "place" in theory guiding management and resource politics.
Beland Lindahl, Karin
core  

Dundee Discussion Papers in Economics 253:Spatial Interactions in Hedonic Pricing Models: The Urban Housing Market of Aveiro, Portugal [PDF]

, 2011
Spatial heterogeneity, spatial dependence and spatial scale constitute key features of spatial analysis of housing markets. However, the common practice of modelling spatial dependence as being generated by spatial interactions through a known spatial ...
Bhattacharjee, Arnab, Marques, Joao Lourenco, de Castro, Eduardo Anselmo, Anselmo de Castro, Eduardo   +3 more
core   +1 more source