Results 121 to 130 of about 17,568,133 (310)
Early and Sustained Improvements in Sense of Smell With Tezepelumab Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyps (WAYPOINT)
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background
Loss of smell is a principal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), affecting health‐related quality of life and posing a safety hazard. Methods
WAYPOINT (NCT04851964), a phase 3, multicenter trial in adults with uncontrolled CRSwNP, randomized patients 1:1 to receive tezepelumab 210 mg or placebo ...Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose +14 morewiley +1 more sourceAppropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background
Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods
Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...Asher C. Park, Brooke N. Gleason, Eli Stein, Saied Ghadersohi, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan +9 morewiley +1 more sourceAlbiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.
The Lancet, 2018 Adrian F. Hernandez, Jennifer B. Green, Salim Janmohamed, R. D'Agostino, C. Granger, N. Jones, Lawrence A Leiter, A. Rosenberg, K. Sigmon, M. Somerville, Karl M Thorpe, J. McMurray, S. Prato, J. McMurray, R. D'Agostino, C. Granger, Adrian F. Hernandez, Lawrence A Leiter, R. Califf, R. Holman, D. DeMets, M. Riddle, S. Goodman, D. McGuire, K. Alexander, A. DeVore, C. Melloni, Chetan R. Patel, D. Kong, Gerald S Bloomfield, M. Roe, P. Tricoci, R. Harrison, R. Lopes, R. Mathews, R. Mehta, W. S. Jones, S. Vemulapalli, T. Povsic, Zubin J. Eapen, K. Dombrowski, B. Kolls, Dedrick Jordan, A. Ambrosy, S. Greene, Aditya Mandawat, J. Shavadia, L. Cooper, Abhinav Sharma, P. Guimarães, D. Friedman, Matt Wilson, P. Endsley, T. Gentry, J. Collier, K. Perez, K. James, Jennifer E. Roush, C. Pope, Christina Howell, Megan Johnson, M. Bailey, Joanna Cole, Teresa Akers, B. Vandyne, Betsy Thomas, J. Rich, Susan Bartone, G. Beaulieu, Kim Brown, T. Chau, Tamra Christian, Rebecca Coker, Deborah Greene, Trevorlyn Haddock, Wendy M. Jenkins, Ghazala Haque, M. Marquess, Jean Pesarchick, Renee Rethaford, Allegra Stone, F. A. Kawas, Michelle Anderson, R. Enns, I. Sinay, C. Mathieu, Victor Yordanov, I. Hramiak, M. Haluzík, S. Galatius, B. Guerci, M. Nauck, I. Migdalis, Choon Beng Kathryn Tan, G. Kocsis, A. Giaccari, Moon-Kyu Lee, E. Muñoz, J. Cornel, K. Birkeland, M. Pinto, L. Tirador, M. Olesińska-Mader, M. Shestakova, L. Distiller, J. López-Sendón, B. Eliasson, C. Chiang, S. Srimahachota, B. Mankovsky, M. A. Bethel, K. Dungan, M. Kosiborod, A. Alvarisqueta, J. Baldovino, D. Besada, Pedro R F Calella, M. C. Cantero, Patricia R. Castaño, A. Chertkoff, J. Cuadrado, L. D. Loredo, A. Domínguez, Maria Vanesa Español, H. Finkelstein, G. Frechtel, José Fretes, Natalia Garrido Santos, Joaquin Gonzalez, M. Litvak, Juan Loureyro, L. Maffei, N. Maldonado, D. Gasparini, Silvia Orio, F. P. Manghi, Nelson Rodriguez Papini, Jorgelina Sala, P. Schygiel, G. Sposetti, M. Ulla, Fernando Verra, Silvina Zabalua, C. Zaidman, L. Crenier, Corinne Debroye, Francis Duyck, A. Scheen, L. Gaal, C. Vercammen, V. Damyanova, S. Dimitrov, Snezhina Kovacheva, L. Lozanov, V. Margaritov, Rositsa Mihaylova-Shumkova, A. Nikolaeva, Zhasmina Stoyanova, R. Akhras, Y. Beaudry, J. Bédard, J. Berlingieri, Raja Chehayeb, S. Cheung, James Conway, J. Cusson, A. D. Siega, R. Dumas, P. Dzongowski, Murdo Ferguson, D. Gaudet, François R. Grondin, Anil Gupta, M. Gupta, F. Halperin, P. Houle, Michael Jones, S. Kouz, Christopher Kovacs, D. Landry, E. Lonn, W. O’Mahony, Sean D. Peterson, D. Reich, Allan M. Rosenbloom, F. St-Maurice, B. Tugwell, S. Vizel, V. Woo, T. Brychta, V. Čech, E. Dvořáková, T. Edelsberger, Katarína Halčiaková, J. Křížová, J. Laštůvka, Martin Piperek, Vera Prymkova, L. Raclavská, Elena Šilhová, R. Urbánek, J. Vrkoč, U. Andersen, J. Brønnum-Schou, J. Hove, J. Jensen, L. Køber, O. Kristiansen, Per Lund, T. Melchior, O. Nyvad, M. Schou, Alain Boye, Didier Cadinot, D. Gouet, P. Henry, L. Kessler, J. Lalau, C. Petit, J. Thuan, C. Voinot, J. Vouillarmet, C. Axthelm, Dirk Berger, T. Bieler, A. Birkenfeld, Jochen Bott, K. Busch, K. Caca, Julia Chevts, Torsten Donaubauer, Rudolf Erlinger, K. Funke, J. Grosskopf, A. Hagenow, Monika Hamann, M. Hartard, Peter Heymer, Wolfgang Huppertz, Gabriele Illies, S. Jacob, T. Jung, Gerd Kahrmann, P. Kast, M. Kellerer, H. Kempe, A. Khariouzov, G. Klausmann, C. Klein, Uwe Kleinecke-Pohl, Klaus Kleinertz, Thorsten Koch, Christine Kosch, B. Lorra, J. Luedemann, Matthias Luttermann, S. Maxeiner, K. Milek, Andre Moelle, G. Neumann, Ruth Nischik, Edith Oehrig-Pohl, Georg Plassmann, Lars Pohlmeier, Felix Proepper, Stefan Regner, Werner Rieker, L. Rose, Holger Samer, J. Sauter, F. Schaper, Clemens Schiffer, Juergen Schmidt, B. Scholz, J. Schulze, A. Segner, J. Seufert, Helena Sigal, Joerg Steindorf, Juergen Stockhausen, Petra Stuebler, Heidrun Taeschner, D. Tews, D. Tschoepe, Karl Wilhelm, H. Zeller-Stefan, Iakovos Avramidis, S. Bousboulas, M. Bristianou, G. Dimitriadis, M. Elisaf, K. Kotsa, A. Melidonis, A. Mitrakou, E. Pagkalos, N. Papanas, A. Pappas, C. Sampanis, N. Tentolouris, A. Tsapas, G. Tzatzagou, R. Ozaki, C. Hajdu, E. Harcsa, László Konyves, J. Mucsi, Z. Pauker, G. Petró, Zsolt Plés, K. Révész, V. Sándor, V. Vass, A. Avogaro, M. Boemi, R. Bonadonna, A. Consoli, S. Cosmo, P. Bartolo, F. Dotta, S. Frontoni, Marianna Galetta, A. Gambineri, C. Gazzaruso, F. Giorgino, D. Lauro, E. Orsi, G. Paolisso, G. Perriello, P. Piatti, A. Pontiroli, P. Ponzani, A. Rivellese, G. Sesti, G. Tonolo, R. Trevisan, C. Ahn, S. Baik, B. Cha, C. Chung, H. Jang, C. Kim, Hye Soon Kim, I. Kim, Eun Young Lee, H. Lee, K. Lee, Keon-Woong Moon, J. Namgung, K. Park, S. Yoo, J. Yu, Edmundo Alfredo Bayram Llamas, Jose-Luis Cervantes-Escárcega, Luis Fernando Flota-Cervera, J. González‐González, S. Pascoe-González, Emilia Susana Pelayo-Orozco, Santiago-Paulino Ramirez-Diaz, A. Saldaña-Mendoza, Carlos Sánchez Jerjes-Díaz, Jose Juan Torres-Colores, Maricela Vidrio-Velázquez, Juan Villagordoa-Mesa, Hugo Peter Beijerbacht, R. G. Groutars, Boudewijn A Hoek, P. Hoogslag, A. Kooy, J. Kragten, A. Lieverse, H. Swart, E. Viergever, Jørn Ahlqvist, J. Cooper, H. Gulseth, Gaute Guttormsen, Cecilie Wium, H. Arbañil, Jorge Calderon, Luis Camacho, Augusto Dextre Espinoza, E. Garrido, A. Luna, Helard Manrique, Frederick Massucco Revoredo, Rolando Gonzales, Luis Zapata Rincon, Carlos Zubiate, G. Ebo, Ellen Morales-Palomares, M. Arciszewska, M. Banach, R. Bijata-Bronisz, T. Dereziński, W. Gadzinski, J. Gajek, Katarzyna Klodawska, E. Krzyżagórska, A. Madej, P. Miękus, Jaroslaw Opiela, Piotr Romanczuk, Anna Siegel, Ewa Skokowska, A. Stankiewicz, Teresa Stasińska, Iwona Trznadel-Morawska, Robert Witek, S. Aksentyev, I. Bondar, I. Demidova, A. Dreval, O. Ershova, G. Galstyan, A. Garganeeva, N. Izmozherova, V. Karetnikova, Marina Kharakhulakh, A. Khokhlov, Z. Kobalava, O. Koshelskaya, E. Kosmacheva, V. Kostin, N. Koziolova, A. Kuzin, Victor Lesnov, T. Lysenko, Valentin Markov, A. Mayorov, S. Moiseev, S. Myasoedova, N. Petunina, A. Rebrov, L. Ruyatkina, Julia Samoylova, O. Sazonova, Natalia E. Shilkina, N. Sokolova, O. Vasilevskaya, N. Verbovaya, E. Vishneva, S. Vorobyev, N. Vorokhobina, O. Zanozina, E. Zhdanova, T. Zykova, L. Burgess, K. Coetzee, S. Dawood, L. Lombard, Ellen Makotoko, R. Moodley, W. Oosthuysen, Mohamed Sarvan, Carlos Calvo Gómez, I. C. Rodríguez, A. Conde, Á. C. Fillat, Guillem Cuatrecasas Cambra, F. Moreno, L. D. T. Parreño, J. D. Lista, José Ramón Domínguez Escribano, S. D. García, J. E. González, José F. Rodriguez, A. Arno, R. G. Huelgas, J. G. Juanatey, A. H. Mijares, V. J. Diaz, E. Gimeno, T. L. Morante, M. Marazuela, N. M. Claros, D. M. Puente, Elena Mena Ribas, J. F. M. Torres, P. M. Raya, Andreu Nubiola Calonge, Xavier Sánchez, J. P. Izuel, Verónica Perea Castilla, A. P. Pérez, Isabel Soto, Miguel Quesada Charneco, A. Simón, J. R. Màs, A. R. Iraeta, M. R. Alvarez, I. Rodríguez, J. S. Ruiz, A. González, F. Madueño, C. T. Serrano, Angels Ulied Armiñana, E. Bachus, Katarina Berndtsson Blom, Kent Eliasson, P. Koskinen +499 moresemanticscholar +1 more sourceFluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors
Angewandte Chemie, EarlyView.Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker +23 morewiley +2 more sourcesRandomized, placebo-controlled, double-blind study assessing the efficacy and safety of paliperidone palmitate in Asian patients with schizophrenia
Neuropsychiatric Disease and Treatment, 2013 Nagahide Takahashi,1 Maayoshi Takahashi,2 Takayuki Saito,3 Misuzu Iizumi,4 Yuki Saito,5 Hiroko Shimizu,6 Taka Matsumura7 1Clinical Responsible Physicians Department, Clinical Science Division, 2Clinical Science Initiative Department, Clinical Science ...Takahashi N, Takahashi M, Saito T, Iizumi M, Saito Y, Shimizu H, Matsumura T +6 moredoaj Analysis of Predefined Safety Events Across Spesolimab Trials in Dermatological and Non-Dermatological Conditions
Dermatology and TherapyIntroduction Spesolimab, a selective, humanised monoclonal antibody targeting the interleukin-36 receptor, is approved for the treatment of generalised pustular psoriasis (GPP).Kenneth B. Gordon, Yayoi Tada, Milan J. Anadkat, Siew Eng Choon, Boni Elewski, Jonathan N. Barker, Arash Mostaghimi, Kilian Eyerich, Ming Tang, Thomas Haeufel, Christian Thoma, Diamant Thaçi +11 moredoaj +1 more source
