Results 81 to 90 of about 17,568,133 (310)

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

open access: yesAdvanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song   +11 more
wiley   +1 more source

El placebo y el efecto placebo

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia
Se denomina placebo a una intervención diseñada para simular una terapia médica, que no tiene efectos específicos para la condición que está siendo aplicada.
Rosa María Lam Díaz   +1 more
doaj  

Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

open access: yesPsychological Medicine, 2018
Background Recent open-label trials show that psychedelics, such as ayahuasca, hold promise as fast-onset antidepressants in treatment-resistant depression.
Fernanda Palhano-Fontes   +22 more
semanticscholar   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Cognitive behavioral therapy for anxiety and related disorders: A meta‐analysis of randomized placebo‐controlled trials

open access: yesDepression and Anxiety, 2018
The purpose of this study was to examine the efficacy of cognitive behavioral therapy (CBT) for anxiety‐related disorders based on randomized placebo‐controlled trials.
Joseph K. Carpenter   +5 more
semanticscholar   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

A Wearable Brain–Computer Interface for Mitigating Car Sickness via Attention Shifting

open access: yesAdvanced Science, EarlyView.
Car sickness poses a major challenge in vehicular travel, yet effective nonpharmacological solutions are scarce. We developed a wearable, closed‐loop mindfulness BCI that uses real‐time EEG‐based neurofeedback to shift attention away from motion‐induced discomfort. Validated in real‐car experiments involving >100$>100$ susceptible individuals, over 83%
Jiawei Zhu   +14 more
wiley   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

open access: yesAdvanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai   +6 more
wiley   +1 more source

Randomised controlled trials may underestimate drug effects: balanced placebo trial design.

open access: yesPLoS ONE, 2014
BackgroundIt is an inherent assumption in randomised controlled trials that the drug effect can be estimated by subtracting the response during placebo from the response during active drug treatment.ObjectiveTo test the assumption of additivity.
Karen Lund   +4 more
doaj   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

open access: yesAdvanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

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