Results 101 to 110 of about 748,749 (317)

Mechanisms of Perceived Treatment Assignment and Subsequent Expectancy Effects in a Double Blind Placebo Controlled RCT of Major Depression

Frontiers in Psychiatry, 2018
Objective: It has been suggested that patients' perception of treatment assignment might serve to bias results of double blind randomized controlled trials (RCT).
Johannes A. C. Laferton, Johannes A. C. Laferton, Johannes A. C. Laferton, Sagar Vijapura, Lee Baer, Alisabet J. Clain, Abigail Cooper, George Papakostas, Lawrence H. Price, Linda L. Carpenter, Audrey R. Tyrka, Maurizio Fava, David Mischoulon   +12 more
doaj   +1 more source

Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial [PDF]

, 2000
Objectives To determine the effect of long term inhaled corticosteroids on lung function, exacerbations, and health status in patients with moderate to severe chronic obstructive pulmonary disease.
Spencer, S, Spencer, Sally, Calverley, Peter MA, Jones, Paul W, Jones, PW, Maslen, TK, Burge, P Sherwood, Burge, PS, Calverley, PMA, Maslen, T K, Anderson, JA, Spencer, Sally; id_orcid, Anderson, Julie A   +12 more
core   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Rational Expectations and Market Timing: An Event Study of the China–United States Phase One Trade Deal

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Rational actors constantly incorporate information into their decision‐making behavior. Since there is often a time lag between the announcement of a policy and its implementation, an important question arises: when do rational actors incorporate new information into their market behavior, at the announcement or at the implementation of a ...
Tim Ölkers, Oliver Mußhoff
wiley   +1 more source

Medical expulsive therapy in adults with ureteric colic : a multicentre, randomised, placebo-controlled trial [PDF]

, 2015
RP, KS, KSt, GMa, RT, JB, GMc, AM, MK, KG, and SM report grants from National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme during the conduct of the study.Background Meta-analyses of previous randomised controlled ...
Neil Burgess, Gillies, Katie, Cameron, Sarah, Thomas, Ruth, Thomas Lam, Graeme MacLennan, Terry Clark, Gillies, Kate, Katie Gillies, Lam, Thomas, Mary Kilonzo, Ruth Thomas, Robert Pickard, McPherson, Gladys, Shearer, Kirsty, Kenneth Anson, Kathryn Starr, MacLennan, Graeme, Burr, Jennifer, Jennifer Burr, N'Dow, James, Clark, Terry, McDonald, Alison, Burgess, Neil, Sarah Cameron, John Norrie, Boachie, Charles, Kilonzo, Mary, Alison McDonald, Gladys McPherson, Starr, Kathryn, Charles Boachie, Pickard, Robert, James N'Dow, McClinton, Samuel, Samuel McClinton, Kirsty Shearer, Anson, Kenneth, Norrie, John, Lam, Thomas Boon Leong   +39 more
core   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Growth of Omnichannel Grocery Retailing and Food Prices

Agribusiness, EarlyView.
ABSTRACT This paper examines the effects of the growth of omnichannel grocery retailing on food prices. We first develop a conceptual model of consumer choice and retailer pricing that allows us to evaluate changes in equilibrium prices, quantities, and profits with online channel growth and alternative pricing strategies.
Xiangwen Kong, Metin Çakır, Qingxiao Li   +2 more
wiley   +1 more source

Exploring the Impact of Meat Alternative Labeling Regulations on the U.S. Meat Consumption Patterns

Agribusiness, EarlyView.
ABSTRACT The global demand for conventional meat continues to rise, but it is also associated with substantial environmental and health challenges. In response, meat alternatives have gained popularity, sparking debates over meat alternative labeling regulations. This study investigates the effects of meat alternative labeling regulations in the United
Jeong Hun Ji, Sang Hyeon Lee
wiley   +1 more source

Do Politically Motivated Import Bans Leave Lasting Scars? Evidence From Australian–Chinese Beef Trade

Agribusiness, EarlyView.
ABSTRACT In May 2020, China abruptly suspended imports from several major Australian beef processors, escalating a diplomatic dispute between the two countries. This trade measure disrupted one of the largest beef export relationships in the world almost overnight.
K. Aleks Schaefer, Youngjune Kim
wiley   +1 more source