Results 81 to 90 of about 748,749 (317)
Background Variation in the way information about potential trial intervention benefits and harms is conveyed within patient information leaflets can cause avoidable information-induced (‘nocebo’) harm, research waste, and may be unethical. Objectives To
Jeremy Howick +8 more
doaj +1 more source
Randomisation is an integral component of any sensible clinical trial. Randomisation is the only way we can be sure that the patients have been allocated into the treatment arms with as minimum bias as possible, and that the treatment arms are similar ...
Jesca M. Batidzirai
doaj +1 more source
Clinicians’ and family members’ feelings and perceptions about a treatment may influence their judgments about its ...
Grelotti, David J, Kaptchuk, Ted J
openaire +3 more sources
Who responds to a placebo? Factors associated with response to placebo during a double-blind randomised controlled trial [PDF]
INTRODUCTION: The placebo effect, a desirable outcome resulting from a person’s expected and/or learned response to a treatment or situation, may significantly influence the interpretation of double-blind, randomised controlled trials (RCT). High placebo
Hurst, P., Coleman, D., Saunders, S.
core
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in giant cell arteritis (GCA) patients. Methods This multicentre retrospective study included patients with GCA who received secukinumab at 14 Italian centres with at least 6 months of follow‐up.
Luca Iorio +29 more
wiley +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Ketamine Usage Effectivity on Treatment-Resistant Depression Diagnosed Patients: a Scoping Review
Introductions: In Indonesia, a median of 6.1% of people diagnosed with depression disorder are people over 15 years old. Only 9% of that amount underwent medical treatment, while the rest, 91%, did not undergo treatment for their depressive conditions ...
Satrio Wahyu Nugroho +3 more
doaj +1 more source
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Placebo and nocebo effects in sport [PDF]
Placebo and nocebo effects can significantly influence sport performance. In the past two decades, research has identified various neurobiological mechanisms of its response and how an athlete’s expectation and previous experiences, can alter the ...
Hurst, P.
core
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source

