Results 61 to 70 of about 1,110,077 (212)

Placebo and Nocebo Effects in Motor Performance: An Overview of Reviews

Brain and Behavior
Objectives To assess and synthesize the effect size and quality of the literature on the placebo and nocebo effects on motor performance and motor‐related perceptive responses. Design Umbrella review.
Cayque Brietzke, Wesley Alves Ribeiro, Paulo Estevão Franco‐Alvarenga, Raul Canestri, Ìtalo Vínicius, Gustavo Vasconcelos, Julio Cesario, Nelson Carvas Junior, Vitor de Salles Painelli, Flávio Oliveira Pires   +9 more
doaj   +1 more source

Erenumab in chronic migraine: Patient-reported outcomes in a randomized double-blind study. [PDF]

, 2019
OBJECTIVE: To determine the effect of erenumab, a human monoclonal antibody targeting the calcitonin gene-related peptide receptor, on health-related quality of life (HRQoL), headache impact, and disability in patients with chronic migraine (CM). METHODS:
Cheng, Sunfa, Desai, Pooja, Lenz, Robert, Leonardi, Dean K., Lipton, Richard B., Mikol, Daniel D., Nilsen, Jon, Reuter, Uwe, Silberstein, Stephen, Stewart, Walter F., Tepper, Stewart J.   +10 more
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Rectal Diazepam for Repetitive Seizures

Pediatric Neurology Briefs, 1998
The effectiveness and safety of a single-dose Diastat (diazepam rectal gel) for treating clusters of acute repetitive seizures in a nonmedical setting by caregivers was evaluated by a multicenter, double-blind study at Oregon Health Sciences University ...
J Gordon Millichap
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Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]

, 2005
This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony, Holz, Olaf, Janicki, Stanislawa, Jörres, Rudolf A., Kanniess, Frank, Magnussen, Helgo, Richter, Kai, Simpson, Kathy J., Tal-Singer, Ruth, Vessey, Rupert S. J.   +9 more
core   +1 more source

Prophylactic use of carvedilol to prevent ventricular dysfunction in patients with cancer treated with doxorubicin [PDF]

, 2018
Objective: Deterioration in ventricular function is often observed in patients treated with anthracyclines for cancer. There is a paucity of evidence on interventions that might provide cardio-protection.
Abrar, Mohammed Burhan, Abuosa, Ahmed Mohamed, Ahmed, Adel H., Andejani, Abdulwahab, Cleland, John G.F., Elshiekh, Ayman Hassan, Kholeif, Mona A., Kinsara, Abdulhalim Jamal, Qureshi, Kahekashan   +8 more
core   +1 more source

Elbasvir/Grazoprevir for HCV Infection in Russia: A Randomized Trial

Hepatic Medicine: Evidence and Research, 2020
Konstantin Zhdanov,1 Vasily Isakov,2 Eduard Burnevich,3 Svetlana Kizhlo,4 Igor Bakulin,5 Vadim Pokrovsky,6 Liwen Liang,7 Peggy Hwang,7 Rohit Talwani,7 Barbara A Haber,7 Michael N Robertson7 1Military Medical Academy n.a. S.M. Kirov, St.
Zhdanov K, Isakov V, Burnevich E, Kizhlo S, Bakulin I, Pokrovsky V, Liang L, Hwang P, Talwani R, Haber BA, Robertson MN   +10 more
doaj  

A comparative study between the efficacy of systemic meglumine antimoniate therapy with standard or low dose plus oral omiprazole in the treatment of cutaneous leishmaniasis [PDF]

Journal of Vector Borne Diseases, 2008
Background & objectives: Pentavalent antimony compounds are the first line of drugs in the treatment of cutaneous leishmaniasis. However, because of their potential toxic effects, many investigations are performed to find an effective and safe treatment ...
M.A. Nilforoushzadeh, F. Jaffary, N. Ansari, A.H. Siadat, Z. Nilforoushan, A. Firouz   +5 more
doaj  

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. [PDF]

, 2013
BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3,
CHEST-1 Study Group,, D'Armini, AM, Fritsch, A, Ghofrani, HA, Grimminger, F, Hoeper, MM, Jansa, P, Kim, NH, Mayer, E, Neuser, D, Simonneau, G, Wang, C, Weimann, G, Wilkins, MR   +13 more
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Developing evidence-based guidelines for describing potential benefits and harms within patient information leaflets/sheets (PILs) that inform and do not cause harm (PrinciPILs)

Health Technology Assessment
Background Variation in the way information about potential trial intervention benefits and harms is conveyed within patient information leaflets can cause avoidable information-induced (‘nocebo’) harm, research waste, and may be unethical. Objectives To
Jeremy Howick, Martina Svobodova, Shaun Treweek, Katie Gillies, Adrian Edwards, Peter Bower, Jennifer Bostock, Nina Jacob, Kerenza Hood   +8 more
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Randomisation in a clinical trial: is it feasible in the Ebola crisis? If it is, then which method is suitable?

Southern African Journal of Infectious Diseases, 2016
Randomisation is an integral component of any sensible clinical trial. Randomisation is the only way we can be sure that the patients have been allocated into the treatment arms with as minimum bias as possible, and that the treatment arms are similar ...
Jesca M. Batidzirai
doaj   +1 more source