Results 61 to 70 of about 748,749 (317)

Historical Aspects of Placebo Analgesia

, 2013
The placebo effect has been a topic of interest in medicine for many hundreds of years. A historical evaluation of the topic demonstrates how the origin of the word, and its initial use in society and in medicine, has shaped its meaning over many years ...
Damien Finniss, Finniss, Damien
core   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Placebo and Nocebo Effects in Motor Performance: An Overview of Reviews

Brain and Behavior
Objectives To assess and synthesize the effect size and quality of the literature on the placebo and nocebo effects on motor performance and motor‐related perceptive responses. Design Umbrella review.
Cayque Brietzke, Wesley Alves Ribeiro, Paulo Estevão Franco‐Alvarenga, Raul Canestri, Ìtalo Vínicius, Gustavo Vasconcelos, Julio Cesario, Nelson Carvas Junior, Vitor de Salles Painelli, Flávio Oliveira Pires   +9 more
doaj   +1 more source

Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression [PDF]

, 2012
Background: Randomized, double-blind, placebo-controlled trials constitute the gold standard in clinical research when testing the efficacy of new psychopharmacological interventions in the treatment of major depression.
Berger Michael, Dittmann, Sandra, Riedel Michael, Sophia, Frangou, Emanuel Severus, Bauer Michael, Severus, Emanuel, Pfennig Andrea, Florian Seemüller, Sophia Frangou, Michael, Bauer, Michael Bauer, Michael Riedel, Berger, Michael, Michael, Obermeier, Andrea, Pfennig, Michael Obermeier, Obermeier Michael, Seemüller Florian, Andrea Pfennig, Michael Berger, Hans-Jürgen, Möller, Dittmann Sandra, Michael, Riedel, Severus Emanuel, Frangou Sophia, Seemüller, Florian, Möller Hans-Jürgen, Sandra Dittmann, Hans-Jürgen Möller   +29 more
core   +2 more sources

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

EL PLACEBO: LUCES Y SOMBRAS Placebo: Lights and shadows

Revista Habanera de Ciencias Médicas, 2008
Se realiza una revisión sobre el placebo definiéndose su concepto, así como del efecto placebo, sus reacciones en el organismo, utilidad en las investigaciones, sus posibles usos en la práctica médica y los peligros de su empleo.
José Díaz Novás
doaj  

Rectal Diazepam for Repetitive Seizures

Pediatric Neurology Briefs, 1998
The effectiveness and safety of a single-dose Diastat (diazepam rectal gel) for treating clusters of acute repetitive seizures in a nonmedical setting by caregivers was evaluated by a multicenter, double-blind study at Oregon Health Sciences University ...
J Gordon Millichap
doaj   +1 more source

Rethinking placebo in psychiatry: The range of placebo effects

, 2013
This article, the first of two on placebo effects, provides a broad overview of placebo in the field of medicine. A brief conceptual history is followed by some basic facts about placebos. Problems of definition are identified.
St John-Smith, Paul, Rampes, Hagen, McQueen, Daniel, Cohen, Sarah   +3 more
core   +1 more source

Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial [PDF]

, 2008
: Background Infectious complications and associated mortality are a major concern in acute pancreatitis. Enteral administration of probiotics could prevent infectious complications, but convincing evidence is scarce. Our aim was to assess the effects of
van Eijck, Casper H. J., Rosman, Camiel, Schaapherder, Alexander F. M., Brink, M.A., van Ramshorst, B, Cuesta, Miguel A., van Santvoort, H.C., van Goor, H., Schaapherder, AFM, Besselink, Marc G. H., van der Harst, E, Cuesta, MA, Boermeester, Marja A., Boermeester, MA, van Eijck, CH, Witteman, Ben J. M., Schaapherder, A.F.M., Besselink, MGH, van der Harst, E., Akkermans, Louis M. A., van der Harst, Erwin, Buskens, E., Rosman, C., Dejong, C.H.C., Wahab, Peter J., Laarhoven, C.J.H.M. van, Nieuwenhuijs, V.B., Ploeg, RJ, Besselink, M.G.H., Witteman, BJM, Bollen, TL, Timmerman, Harro M., Timmerman, H.M., van Laarhoven, CJ, Ploeg, R.J., Dejong, CH, Buskens, Erik; id_orcid, Besselink, M.G., van Eijck, Casper, Van Eijck, GHJ, Timmerman, HM, Buskens, E, Gooszen, H.G., Van Laarhoven, CJHM, Akkermans, L.M., Grp, DAPS, Schaapherder, AF, Santvoort, H.C. van, Nieuwenhuijs, VB, Boermeester, M.A., Cuesta, M.A., Nieuwenhuijs, Vincent B., Bollen, T.L., Akkermans, LM, Wahab, PJ, Dejong, CHC, Gooszen, Hein G., van Ramshorst, B., Witteman, B.J., Akkermans, L.M.A., van Laarhoven, C.J.H.M., Dejong, C.H., Dejong, Cornelis H. C., Wahab, P.J., Eijck, C.H. van, van Laarhoven, C.J., Gooszen, HG, van der Harst, E (Erwin), Witteman, B.J.M., Bollen, Thomas L., Harst, E. van der, van Goor, H, Brink, M., van Ramshorst, Bert, Rosman, C, Buskens, Erik, van Laarhoven, Cees J. H. M., Brink, Menno A., Ramshorst, B. van, Ploeg, Rutger, van Goor, Harry, van Eijck, C.H.J., Goor, H. van, Besselink, MG, Brink, MA, Schaapherder, A.F., Akkermans, LMA, van Eijck, C.H., van Santvoort, HC, van Santvoort, Hjalmar C., Witteman, BJ, van Eijck, van, Ploeg, Rutger J.   +92 more
core   +2 more sources

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source