Results 51 to 60 of about 677,625 (318)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

The effect of alcohol and placebo on post-error adjustments

Frontiers in Human Neuroscience, 2013
Several studies have shown detrimental effects of alcohol on post-error adjustments. In contrast to previous studies, which focused on only one aspect of post-error adaptive behavior, we compared the effect of alcohol and placebo on post-error slowing ...
Klaas eBombeke, Nathalie eSchouppe, Wout eDuthoo, Wim eNotebaert   +3 more
doaj   +1 more source

Sex Differences in the Blood Oxygen Level-Dependent Signal to Placebo Analgesia and Nocebo Hyperalgesia in Experimental Pain: A Functional MRI Study

Frontiers in Behavioral Neuroscience, 2021
ObjectivePlacebo as well as nocebo responses are widely found in scientific research and clinical practice. Growing evidence suggests sex differences in placebo as well as nocebo responses.
Yu Shi, Yu Shi, Hongrui Zhan, Hongrui Zhan, Yanyan Zeng, Yanyan Zeng, Shimin Huang, Shimin Huang, Guiyuan Cai, Guiyuan Cai, Jianming Yang, Wen Wu, Wen Wu   +12 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Comparative Efficacy and Safety of JAK Inhibitors in the Management of Rheumatoid Arthritis: A Network Meta-Analysis

Pharmaceuticals
Background/objective: Janus Kinase inhibitors (JAKinibs) are effective and well-tolerated targeted therapies for rheumatoid arthritis (RA). The comparative efficacy and safety of different JAKinibs remains unclear.
Hani M. Almoallim, Mohammed A. Omair, Sameh A. Ahmed, Kota Vidyasagar, Bisher Sawaf, Mohamed A. Yassin   +5 more
doaj   +1 more source

Placebo készítmények a gyakorlatban és egy tabletta előállításának bemutatása konkrét példán keresztül

, 2020
Diplomamunkám során célul tűztem ki a placebo-jelenség körbejárását, a placebo-hatás hátterében zajló folyamatok feltárását. Mindemellett lehetőséget kaptam a Gyógyszertechnológiai Tanszéken a témavezetőmmel együtt egy kísérleti, laktózt tartalmazó és ...
Tóth, Fruzsina Judit
core  

Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial [PDF]

, 2008
: Background Infectious complications and associated mortality are a major concern in acute pancreatitis. Enteral administration of probiotics could prevent infectious complications, but convincing evidence is scarce. Our aim was to assess the effects of
van Eijck, Casper H. J., Rosman, Camiel, Schaapherder, Alexander F. M., Brink, M.A., van Ramshorst, B, Cuesta, Miguel A., van Santvoort, H.C., van Goor, H., Schaapherder, AFM, Besselink, Marc G. H., van der Harst, E, Cuesta, MA, Boermeester, Marja A., Boermeester, MA, van Eijck, CH, Witteman, Ben J. M., Schaapherder, A.F.M., Besselink, MGH, van der Harst, E., Akkermans, Louis M. A., van der Harst, Erwin, Buskens, E., Rosman, C., Dejong, C.H.C., Wahab, Peter J., Laarhoven, C.J.H.M. van, Nieuwenhuijs, V.B., Ploeg, RJ, Besselink, M.G.H., Witteman, BJM, Bollen, TL, Timmerman, Harro M., Timmerman, H.M., van Laarhoven, CJ, Ploeg, R.J., Dejong, CH, Buskens, Erik; id_orcid, Besselink, M.G., van Eijck, Casper, Van Eijck, GHJ, Timmerman, HM, Buskens, E, Gooszen, H.G., Van Laarhoven, CJHM, Akkermans, L.M., Grp, DAPS, Schaapherder, AF, Santvoort, H.C. van, Nieuwenhuijs, VB, Boermeester, M.A., Cuesta, M.A., Nieuwenhuijs, Vincent B., Bollen, T.L., Akkermans, LM, Wahab, PJ, Dejong, CHC, Gooszen, Hein G., van Ramshorst, B., Witteman, B.J., Akkermans, L.M.A., van Laarhoven, C.J.H.M., Dejong, C.H., Dejong, Cornelis H. C., Wahab, P.J., Eijck, C.H. van, van Laarhoven, C.J., Gooszen, HG, van der Harst, E (Erwin), Witteman, B.J.M., Bollen, Thomas L., Harst, E. van der, van Goor, H, Brink, M., van Ramshorst, Bert, Rosman, C, Buskens, Erik, van Laarhoven, Cees J. H. M., Brink, Menno A., Ramshorst, B. van, Ploeg, Rutger, van Goor, Harry, van Eijck, C.H.J., Goor, H. van, Besselink, MG, Brink, MA, Schaapherder, A.F., Akkermans, LMA, van Eijck, C.H., van Santvoort, HC, van Santvoort, Hjalmar C., Witteman, BJ, van Eijck, van, Ploeg, Rutger J.   +92 more
core   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Rethinking placebo in psychiatry: The range of placebo effects

, 2013
This article, the first of two on placebo effects, provides a broad overview of placebo in the field of medicine. A brief conceptual history is followed by some basic facts about placebos. Problems of definition are identified.
St John-Smith, Paul, Rampes, Hagen, McQueen, Daniel, Cohen, Sarah   +3 more
core   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source