Results 71 to 80 of about 1,110,077 (212)
Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial [PDF]
, 2009 <br>Background: Metformin reduces cardiovascular risk in patients with type 2 diabetes seemingly independent of lowering blood glucose concentration. We assessed the cardiovascular effects of metformin in individuals without type 2 diabetes.</br&Eddy, Despres, Grundy, Bird, Seifarth, Nathan, Fontbonne, Charles, Holman, Kooy, Knowler, Alberti, Vergeer, Touboul, Liang, Spence, Levey, Meaney, Taylor, Selvin, Boussageon, Sjöström, Shyangdan, de Jager, Bots, Taylor, Boden, Huang, Baigent, Lorenz, Mazzone, Taylor, Lonn, Lexis +33 morecore +5 more sourcesIntravenous meloxicam for the treatment of moderate to severe acute pain: a pooled analysis of safety and opioid-reducing effects. [PDF]
, 2019 BACKGROUND AND OBJECTIVES: To describe the safety and tolerability of intravenous meloxicam compared with placebo across all phase II/III clinical trials.Bergese, Sergio, Du, Wei, Gan, Tong J., Hobson, Sue, Mack, Randall J., McCallum, Stewart W., Singla, Neil, Viscusi, Eugene R. +7 morecore +1 more sourceOne Year Follow-up of a Randomized, Double-Blind, Placebo-Controlled Trial of Percutaneous Peripheral Nerve Stimulation for Chronic Neuropathic Pain Following Amputation [PDF]
, 2019 INTRODUCTION
Over 85% of patients experience residual limb (RLP) and/or phantom limb (PLP) pain following amputation. Peripheral nerve stimulation (PNS) is a non-opioid approach to relieve postamputation neuropathic pain.Boggs, Josh W, Cohen, Steven P, Crosby, Nate, Desai, Mehul J, Gilmore, Christopher, Hunter, Corey, Ilfeld, Brian M, Kapural, Leonardo, Li, Sean, Mak, John, Nader, Antoun, Rauck, Richard, Rosenow, Joshua M +12 morecore Levosimendan for the prevention of acute organ dysfunction in sepsis [PDF]
, 2016 BACKGROUND Levosimendan is a calcium-sensitizing drug with inotropic and other properties that may improve outcomes in patients with sepsis. METHODS We conducted a double-blind, randomized clinical trial to investigate whether levosimendan reduces the ...Al-Beidh, F, Ashby, D, Best-Lane, J, Brealey, D, Breen, A, Cross, M, Gordon, AC, Liu, KD, Mason, AJ, McAuley, DF, McNamee, JJ, Nutt, CL, Orme, RML, Perkins, GD, Reschreiter, H, Santhakumaran, S, Singer, M +16 morecore +2 more sourcesSotatercept safety and effects on hemoglobin, bone, and vascular calcification [PDF]
, 2019 Introduction: Patients with end-stage kidney disease (ESKD) exhibit anemia, chronic kidney disease‒mineral bone disorder (CKD-MBD), and cardiovascular disease.Connarn, Jamie N, Coyne, Daniel W, Dellanna, Frank, Giuseppi, Ana Carolina, Hruska, Keith A, Malluche, Hartmut H, Sherman, Matthew L, Singh, Hem N, Smith, William T +8 morecore +1 more sourceChlorpromazine versus placebo for schizophrenia [PDF]
, 2014 BackgroundChlorpromazine, formulated in the 1950s, remains a benchmark treatment for people with schizophrenia.ObjectivesTo review the effects of chlorpromazine compared with placebo, for the treatment of schizophrenia.Search methodsWe searched the ...Abrams, Abse, Acker, Adams, Affleck, Agarwal, Ahmed, Akimoto, Alpert, Alpert, Alson, Altman, Aman, American Psychiatric Association, American Psychiatric Association, Amin, Ananth, Andrews, Ashcroft, Awad, Ayers, Azima, B, Bagadia, Baker, Ban, Ban, Becker, Beech, Belmont, Benaim, Bennett, Birchwood, Bishop, Bland, Blumberg, Blumberg, Boer, Boissel, Bollini, Borison, Borison, Boullin, Bowes, Bressler, Brizer, Burnett, Cabrera Gomez, Caffey, Caffey, Caffey, Caldwell, Campbell, Campbell, Cardone, Casey, Casey, Chacon, Chacon, Childers, Chong, Chouinard, Chouinard, Chouinard-G, Claghorn, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Clark, Cobb, Cohen, Cole, Cole, Coons, Cooper, Cowden, Crane, Crane, Crane, Crow, Curry, Cutler, Dally, Danion, Daston, Daston, Davies, Davis, Dean, Dean, Denber, Denber, Denber, Desager, Divine, Donner, Douglas, Downing, Dube, Egger, Eitan, Ekdawi, Elbourne, Elkes, Engelhardt, Engelhardt, Engelhardt, Engelhardt, Engelhardt, Feldman, Fink, Fink, Fink, Fleming, Fleming, Foote, Forrest, Freed, Freedman, Freedman, Freedman, Freeman, Freeman, Freeman, Friedhoff, Fromm, Furukawa, Gaitz, Galbrecht, Galdi, Gallant, Gallant, Gardner, Gardos, Gardos, Gardos, Garfield, Garmezy, Gauthier, Gendron, Gibbs, Gibbs, Gilgash, Godwin-Austen, Goldberg, Goldberg, Goldberg, Goldberg, Goldberg, Goldberg, Goldman, Good, Graupner, Graupner, Green, Green, Greenberg, Griffiths, Grozier, Grygier, Gulliford, Guy, Guy, Gwynne, Hall, Hambrecht, Hamill, Hamilton, Hammond, Hamner, Hankoff, Hankoff, Hanlon, Hanlon, Harper, Hartley, Hartley, Hartley, Hartley, Hartmann, Haskell, Heilizer, Hekimian, Herrera, Herrmann, Herrmann, Herz, Higgins, Hill, Hine, Hoffer, Hoffer, Hogarty, Hogarty, Hogarty, Hogarty, Hogarty, Hogarty, Hollis, Hollister, Hollister, Hollister, Holt, Honigfeld, Hopkin, Hrushka, Huang, Hughes, Hurst, Hussar, Itil, Itil, Jadad, Jenicek, Jia, Johnstone, Johnstone, Jones, Jones, Joseph, Joshi, Jusic, Kabes, Kammerer, Kane, Kaplan, Kaplan, Kay, Kendler, Keskiner, Kim, Kimbell, King, King, Klein, Klein, Klein, Klein, Klein, Kopell, Kordas, Kornetsky, Kornetsky, Kornetsky, Kornetsky, Korol, Kovitz, Kramer, Kugler, Kupfer, Kurland, Kurland, Kurland, Kurland, Kurland, Kurland, Laborit, Lampe, Latz, Laurian, Leff, Leff, Leszek, Letemendia, Leucht, Leucht, Leucht, Levenstein, Levin, Levine, Levita, Lewis, Li, Liberman, Little, Long, Loranger, Lorr, Lucero, Lyberi, MacMillan, Maculans, Mahal, Majewski, Mandel, Marjerrison, Marrazzi, Marshall, Mason-Browne, Mason-Browne, Mathur, Mattila, McClelland, Mefferd, Melnyk, Merry, Michaux, Millar, Milne, Milstein, Milton, Mirsky, Mitchell, Mitchell, Moher, Monteleone, Morgenstern, Morton, Moss, Neal, Newbold, Nishikawa, Odejide, Okuma, Orzack, Osmakova, Overall, Paredes, Park, Pasamanick, Patterson, Payne, Peet, Peet, Pennington, Pfeiffer, Pietzcker, Pigache, Pigache, Pigache, Planansky, Platz, Pleasure, Pollack, Pollard, Praag, Praag, Prien, Prien, Prien, Prien, Primac, Quigley, Quinn, Raaska, Ragland, Raja, Ramu, Ramu, Rappaport, Rappaport, Rappaport, Rathod, Ray, Raymond, Reardon, Remr, Remr, Reschke, Rifkin, Rinaldi, Rivera Calimlim, Rosen, Rosen, Rosen, Rosenheck, Rosenthal, Rosner, Rudy, Rudy, Sainz, Sakalis, Saletu, Salisbury, Saretsky, Schiele, Schiele, Schmidt, Schooler, Schooler, Schulz, Schünemann, Seager, Sedvall, Serafetinides, Serafetinides, Serafetinides, Serafetinides, Serafetinides, Serafetinides, Serafetinides, Serafetinides, Shaskan, Shaskan, Shawver, Shepherd, Shopsin, Shopsin, Silver, Simon, Simon, Simpson, Simpson, Singh, Singh, Singh, Singh, Singh, Small, Smith, Smith, Smith, Smith, Somerville, Sommerness, South-East Region (Scotland) Therapeutic Trials Committee, Soyka, Spiegel, Spohn, Spohn, Sugerman, Sun, Syvalahti, Szymanski, Szymanski, Talbot, Tang, Tang, Tassis, Teja, Tenenblatt, Terminska, Tetreault, Tetreault, Tetreault, Thornley, Thornley, Thorpe, Tourlentes, Troshinsky, Turner, Turner, Ukoumunne, Urquhart, Vaughan, Vinar, Vinar, Volavka, Walsh, Warner, Weckowicz, Weir, Welbel, Whitehead, Wilcott, Wilson, Winkelman, Winter, Wode-Helgodt, Wold, Wolpert, Wyatt, Xia, Xiong, Yan, Yang, Yorkston, Yuan-Guang, Zeller, 王强, 金建烽 +486 morecore +1 more sourceEfficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): a multicentre, parallel-group, randomised placebo-controlled trial
Efficacy and Mechanism Evaluation, 2015 Background: Diarrhoea-predominant irritable bowel syndrome (IBS-D) is a common outcome after inflammation due to bacterial gastroenteritis. Several studies have shown ongoing immune activation in the mucosa of patients with IBS-D and a number of studies ...Ching Lam, Wei Tan, Matthew Leighton, Margaret Hastings, Melanie Lingaya, Yirga Falcone, Xiaoying Zhou, Luting Xu, Peter Whorwell, Andrew F Walls, Abed Zaitoun, Alan Montgomery, Robin C Spiller +12 moredoaj +1 more sourceAged garlic extract reduces low attenuation plaque in coronary arteries of patients with diabetes: A randomized, double-blind, placebo-controlled study. [PDF]
, 2020 Several previous studies have demonstrated that aged garlic extract (AGE) inhibits the progression of coronary artery calcification and non-calcified plaque (NCP) in the general population.Almeida, Shone, Birudaraju, Divya, Budoff, Matthew J, Cherukuri, Lavanya, Cu, Benedict, Flores, Ferdinand, Hamal, Sajad, Jayawardena, Eranthi, Johanis, Amit, Kinninger, April, Nakanishi, Rine, Shaikh, Kashif, Sheikh, Mohammed Salman, Shekar, Chandana +13 morecore Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study [PDF]
, 2011 Background and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication.Beecher, Belafsky, Birring, Blondeau, Chang, Corley, Decalmer, DeVault, Dial, Eccles, Eherer, Everett, Faruqi, FitzGerald, Gilard, Gulmez, Hemmink, Herzig, Ing, Irwin, Irwin, Irwin, Irwin, Juurlink, Laheij, Lenglinger, Mastronarde, Morice, Morice, Morice, Morice, Noordzij, Pratter, Rostami-Hodjegan, Shaheen, Vaezi, Vertigan, Wager, Waring, Wo, Yang, Yearsley +41 morecore +1 more source