Results 91 to 100 of about 748,749 (317)

Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): a multicentre, parallel-group, randomised placebo-controlled trial

Efficacy and Mechanism Evaluation, 2015
Background: Diarrhoea-predominant irritable bowel syndrome (IBS-D) is a common outcome after inflammation due to bacterial gastroenteritis. Several studies have shown ongoing immune activation in the mucosa of patients with IBS-D and a number of studies ...
Ching Lam, Wei Tan, Matthew Leighton, Margaret Hastings, Melanie Lingaya, Yirga Falcone, Xiaoying Zhou, Luting Xu, Peter Whorwell, Andrew F Walls, Abed Zaitoun, Alan Montgomery, Robin C Spiller   +12 more
doaj   +1 more source

The science of the placebo versus placebo science

, 2017
Recent years have been politically tumultuous; elections and referenda are seldom out of the news, and politicians seek ever more extreme positions to gain media attention and votes. It appears widely accepted that we are living in the ‘post-truth’ era.
Beedie, C.
core  

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Effects of vaginal progesterone and placebo on preterm birth and antenatal outcomes in women with singleton pregnancies and short cervix on ultrasound: a meta-analysis

Frontiers in Medicine
BackgroundVaginal progesterone in preterm birth and adverse outcomes caused by cervical insufficiency remains controversial. To address it, the effect of vaginal progesterone on preterm delivery and perinatal outcome of single pregnancy women with short ...
Limin Peng, Limin Peng, Yan Gao, Chengkun Yuan, Hongying Kuang, Hongying Kuang   +5 more
doaj   +1 more source

Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomised placebo-controlled trials [PDF]

, 2007
Background Treatment efficacy of physical agents in osteoarthritis of the knee (OAK) pain has been largely unknown, and this systematic review was aimed at assessing their short-term efficacies for pain relief.
Anne E Ljunggren, Roberta Chow, Chow, Robert, Jan M Bjordal, Lopes-Martins, Rodrigo A.B., Lopes-Martins, RA, Rodrigo AB Lopes-Martins, Bjordal, Jan M, Bogen, B, Johnson Mark I, Ljunggren, AE, Bjordal Jan M, Chow, Roberta , Ljunggren, Anne E, Bjordal, JM, Chow, Roberta, Bogen, Bård, Ljunggren Anne E, Chow, R, Johnson, Mark I., Lopes-Martins, Rodrigo Álvaro Brandão, Ljunggren, Anne Elisabeth, Bjordal, Jan Magnus, Lopes-Martins Rodrigo AB, Johnson, MI, Bogen Bård, Ljunggren, Anne E., Mark I Johnson, Bård Bogen, Lopes-Martins, Rodrigo AB, Johnson, Mark I, Chow Roberta, Bogen, Bård    +32 more
core   +2 more sources

An Interpretable, Data‐Driven, Hierarchical Multi‐Domain Fusion Framework for Classification and Motor Function Scoring in Chronic Ankle Instability

Advanced Science, EarlyView.
An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie, Datao Xu, Zhifeng Zhou, Bas Van Hooren, Huiyu Zhou, Yi Yuan, Xiangli Gao, Monèm Jemni, Liangliang Xiang, Meizi Wang, Justin Fernandez, Tibor J. Goda, Yaodong Gu   +12 more
wiley   +1 more source

COMPARISON OF POSTOPERATIVE PAIN SCORE FOLLOWING TRANSVERSUS ABDOMINIS PLANE BLOCK VERSUS PLACEBO, IN PATIENTS UNDERGOING ELECTIVE TOTAL ABDOMINAL HYSTERECTOMY UNDER GENERAL ANAESTHESIA

Pakistan Armed Forces Medical Journal, 2021
Objective: To compare the mean postoperative pain score following Transversus Abdominis Plane block versus placebo, in patients undergoing elective total Abdominal Hysterectomy under general anaesthesia.
Raja Muhammad Bilal, Bilal Humayun Khan Durrani, Rao Ali Shan Khan   +2 more
doaj  

Hormone Replacement Therapy and Menopause: A Review of Randomized, Double-Blind, Placebo-Controlled Trials

Kaohsiung Journal of Medical Sciences, 2003
Hormone replacement therapy (HRT) is frequently prescribed to healthy women to ameliorate menopausal symptoms. HRT is used long term (≥ 1 year) to prevent chronic disease in older women. The objective of this study was to review the benefits and risks of
Chueh Chang
doaj   +1 more source

Placebo effect: the influence of the psychosocial context on the patient. [PDF]

, 2023
openNegli ultimi anni la ricerca sugli effetti placebo e nocebo ha suscitato molto interesse, divenendo oggetto di numerosi studi. La letteratura vanta considerazioni importanti sul contesto psicosociale che gravita attorno alla persona assistita e sul ...
DA ROS, AURORA
core  

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source