Results 31 to 40 of about 888,393 (367)
Importance Type 2 diabetes is associated with increased cardiovascular (CV) risk. Prior trials have demonstrated CV safety of 3 dipeptidyl peptidase 4 (DPP-4) inhibitors but have included limited numbers of patients with high CV risk and chronic kidney ...
J. Rosenstock+18 more
semanticscholar +1 more source
The Role of Placebo Samples in Observational Studies [PDF]
In an observational study, it is common to leverage known null effect to detect bias. One such strategy is to set aside a placebo sample -- a subset of data immune from the hypothesized cause-and-effect relationship. Existence of an effect in the placebo sample raises concern of unmeasured confounding bias while absence of it corroborates the causal ...
arxiv
Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.
BACKGROUND Dupilumab, a human monoclonal antibody against interleukin-4 receptor alpha, inhibits signaling of interleukin-4 and interleukin-13, type 2 cytokines that may be important drivers of atopic or allergic diseases such as atopic dermatitis ...
E. Simpson+24 more
semanticscholar +1 more source
Illness Expectations Assessment in People with Asthma: A Tool for Explicit and Implicit Beliefs
Francesco Pagnini,1,2 Eleonora Volpato,1,3 Silvia Dell’Orto,1 Cesare Cavalera,1 MariaFrancesca Spina,3 Paolo Banfi3 1Department of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy; 2Department of Psychology, Harvard University,
Pagnini F+5 more
doaj
In their innovative study, Inzlicht and Al-Khindi (2012) demonstrated that participants who were allowed to misattribute their arousal and negative affect induced by errors to a placebo beverage had a reduced error-related negativity (ERN/Ne) compared to
Carmen Cano Rodilla+2 more
doaj +1 more source
Botanical products are frequently sold as dietary supplements and their use by the public is increasing in popularity. However, scientific evaluation of their medicinal benefits presents unique challenges due to their chemical complexity, inherent ...
Kirsten M. Wright+14 more
doaj +1 more source
Can Intracommunicology Assist the Philosophy of the Media? [PDF]
In 2014, the famous researcher and Nobel laureate Bruce Lipton proved that human thoughts, not just thinking, are energy, they are real and have power. “‘Do not doubt that you command your body and mind... If thoughts are weak and life is like that.
Fahira Fejzić-Čengić
doaj +1 more source
Assessing Vaccine Durability in Randomized Trials Following Placebo Crossover [PDF]
Randomized vaccine trials are used to assess vaccine efficacy and to characterize the durability of vaccine induced protection. If efficacy is demonstrated, the treatment of placebo volunteers becomes an issue. For COVID-19 vaccine trials, there is broad consensus that placebo volunteers should be offered a vaccine once efficacy has been established ...
arxiv
Lenvatinib versus placebo in radioiodine-refractory thyroid cancer.
BACKGROUND Lenvatinib, an oral inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, fibroblast growth factor receptors 1 through 4, platelet-derived growth factor receptor α, RET, and KIT, showed clinical activity in a phase 2 study ...
M. Schlumberger+18 more
semanticscholar +1 more source
Background: The main purpose of this study was to evaluate the effectiveness of triamcinolone acetonide (TA) mucoadhesive films versus placebo as a preventive and therapeutic intervention of oral mucositis (OM) induced by radiotherapy for head-and-neck ...
Fahimeh Pakravan+4 more
doaj +1 more source